{
  "id": 5937,
  "label": "tall cell variant thyroid gland papillary carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004103",
  "properties": {
    "xrefs": [
      "DOID:7089",
      "GARD:0023824",
      "MEDGEN:234416",
      "NCIT:C35558",
      "UMLS:C1336695"
    ],
    "synonyms": [
      "tall cell variant papillary carcinoma",
      "tall cell variant thyroid gland papillary carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A morphologic variant of papillary carcinoma of the thyroid gland characterized by the presence of tall malignant follicular cells, arranged in papillary and trabecular patterns. Necrotic changes and high mitotic activity are present."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6803,
      "label": "thyroid gland papillary carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4583,
        16290,
        21537
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3969",
          "EFO:0000641",
          "GARD:0024148",
          "HP:0002895",
          "MEDGEN:66773",
          "NCIT:C4035",
          "ONCOTREE:THPA",
          "SCTID:255029007",
          "UMLS:C0238463"
        ],
        "synonyms": [
          "papillary cancer of the thyroid",
          "papillary cancer of the thyroid gland",
          "papillary cancer of thyroid",
          "papillary cancer of thyroid gland",
          "papillary carcinoma of the thyroid",
          "papillary carcinoma of the thyroid gland",
          "papillary carcinoma of thyroid",
          "papillary carcinoma of thyroid gland",
          "papillary thyroid cancer",
          "papillary thyroid carcinoma",
          "papillary thyroid gland carcinoma",
          "thyroid gland papillary cancer",
          "thyroid gland papillary carcinoma",
          "thyroid papillary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. Radiation exposure is a risk factor and it is the most common malignant thyroid lesion, comprising 75% to 80% of all thyroid cancers in iodine sufficient countries. Diagnostic procedures include thyroid ultrasound and fine needle biopsy. Microscopically, the diagnosis is based on the distinct characteristics of the malignant cells, which include enlargement, oval shape, elongation, and overlapping of the nuclei. The nuclei also display clearing or have a ground glass appearance."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005075"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6803,
      "label": "thyroid gland papillary carcinoma"
    }
  ]
}