{
  "id": 5941,
  "label": "splenic manifestation of leukemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004107",
  "properties": {
    "xrefs": [
      "DOID:710",
      "GARD:0023828",
      "MEDGEN:234813",
      "NCIT:C7296",
      "UMLS:C1336065"
    ],
    "synonyms": [
      "leukaemia (disease) of spleen",
      "leukemia (disease) of spleen",
      "spleen leukaemia (disease)",
      "spleen leukemia (disease)",
      "splenic manifestation of leukemia",
      "splenic leukaemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A leukemia (disease) that involves the spleen."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6789,
      "label": "leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1240",
          "EFO:0000565",
          "HP:0001909",
          "ICD9:207",
          "ICD9:207.8",
          "ICD9:207.80",
          "ICD9:208",
          "ICD9:208.8",
          "ICD9:208.80",
          "ICD9:208.9",
          "ICD9:208.90",
          "ICDO:9800/3",
          "MEDGEN:9725",
          "MESH:D007938",
          "NANDO:2100002",
          "NCIT:C3161",
          "SCTID:93143009",
          "UMLS:C0023418"
        ],
        "synonyms": [
          "blood (leukemia)",
          "leukaemia (disease)",
          "leukemia",
          "leukemia (disease)",
          "leukemia, disease",
          "leukemia, malignant",
          "leukemias",
          "leukemias, general",
          "leukaemia NOS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005059"
    },
    {
      "id": 7558,
      "label": "spleen cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3023,
        4587,
        22946
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:672",
          "EFO:0007491",
          "GARD:0024265",
          "ICD10CM:C26.1",
          "MEDGEN:102271",
          "MESH:D013160",
          "NCIT:C3539",
          "SCTID:127230005",
          "UMLS:C0153470",
          "icd11.foundation:347078862"
        ],
        "synonyms": [
          "spleen neoplasm",
          "splenic neoplasm",
          "cancer of spleen",
          "cancer of the spleen",
          "malignant neoplasm of spleen",
          "malignant neoplasm of the spleen",
          "malignant spleen neoplasm",
          "malignant splenic neoplasm",
          "malignant splenic tumor",
          "malignant splenic tumour",
          "malignant tumor of spleen",
          "malignant tumor of the spleen",
          "malignant tumour of the spleen",
          "spleen cancer",
          "splenic cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the spleen"
      },
      "child_count": 15,
      "reference_id": "MONDO:0005966"
    }
  ],
  "children": [
    {
      "id": 4970,
      "label": "splenic manifestation of prolymphocytic leukemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3282,
        5941,
        6479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4334",
          "GARD:0023310",
          "MEDGEN:277663",
          "NCIT:C7297",
          "UMLS:C1336066"
        ],
        "synonyms": [
          "prolymphocytic leukaemia of spleen",
          "prolymphocytic leukemia of spleen",
          "spleen prolymphocytic leukaemia",
          "spleen prolymphocytic leukemia",
          "splenic manifestation of prolymphocytic leukemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A prolymphocytic leukemia that involves the spleen."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002966"
    },
    {
      "id": 5938,
      "label": "splenic manifestation of hairy cell leukemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5941,
        6479,
        18857
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:709",
          "GARD:0023825",
          "ICD9:202.47",
          "MEDGEN:234812",
          "NCIT:C7301",
          "SCTID:93151007",
          "UMLS:C1336064"
        ],
        "synonyms": [
          "spleen hairy cell leukaemia",
          "spleen hairy cell leukemia",
          "splenic manifestation of hairy cell leukemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A hairy cell leukemia that involves the spleen."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004104"
    }
  ],
  "roots": [
    {
      "id": 6789,
      "label": "leukemia"
    },
    {
      "id": 7558,
      "label": "spleen cancer"
    }
  ]
}