{
  "id": 5988,
  "label": "bladder urachal urothelial carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004163",
  "properties": {
    "xrefs": [
      "DOID:7244",
      "GARD:0023857",
      "MEDGEN:267744",
      "NCIT:C39844",
      "UMLS:C1511207"
    ],
    "synonyms": [
      "bladder urachal urothelial carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A transitional cell carcinoma of the urinary bladder that arises from the urachal epithelium."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5596,
      "label": "bladder urachal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5958",
          "MEDGEN:419015",
          "MESH:C536475",
          "NCIT:C39842",
          "ONCOTREE:URCA",
          "Orphanet:695020",
          "UMLS:C2931202"
        ],
        "synonyms": [
          "bladder urachal cancer",
          "bladder urachal carcinoma",
          "urachal carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Urachal cancer is a type of bladder cancer, making up less than 1% of all bladder cancers. The urachus is a structure normally only present during development in the womb that connects the bellybutton and the bladder. This connection normally disappears before birth, but in some people remains. Urachalcancers are usually diagnosed in adults in their 50's and 60's and may develop at the dome or anterior wall of the bladder, along the midline of the body (including the belly button), and between the pubis symphasis and the bladder.Most urachal cancersare adenocarcinomas (cancers that develop from gland cells).Others may besarcomas (which develop from connective tissue -such as leiomyosarcoma, rhabdomyosarcoma, and malignant fibrous histiocytoma), small cell carcinomas, transitional cell cancer, and mixed neoplasias. Most individuals with urachal cancer have symptoms of with hematuria (blood in urine). Other symptoms may include abdominal pain, a palpable abdominal mass, mucinuria, and bacteriuria. Treatment usually involved surgery to remove the cancer."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003715"
    },
    {
      "id": 7252,
      "label": "bladder transitional cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6727,
        23006
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4006",
          "EFO:0006544",
          "MEDGEN:76013",
          "NCIT:C39851",
          "ONCOTREE:BLCA",
          "SCTID:255109008",
          "UMLS:C0279680"
        ],
        "synonyms": [
          "bladder transitional cell carcinoma",
          "bladder urothelial cancer",
          "bladder urothelial carcinoma",
          "transitional cell carcinoma of the urinary bladder",
          "urinary bladder transitional cell carcinoma",
          "urinary bladder urothelial carcinoma",
          "urothelial carcinoma of the urinary bladder",
          "BLCA"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "The most common morphologic subtype of urinary bladder carcinoma (over 90% of cases). It arises from the transitional epithelium. It most often affects males in their sixth and seventh decades of life. Hematuria is the most common symptom at presentation. Pathologic stage is the strongest predictor of survival."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005611"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5596,
      "label": "bladder urachal carcinoma"
    },
    {
      "id": 7252,
      "label": "bladder transitional cell carcinoma"
    }
  ]
}