{
  "id": 6042,
  "label": "endometrial endometrioid adenocarcinoma with spindled epithelial cells",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004220",
  "properties": {
    "xrefs": [
      "DOID:7436",
      "MEDGEN:234979",
      "NCIT:C27850",
      "UMLS:C1336913"
    ],
    "synonyms": [
      "endometrial endometrioid adenocarcinoma with spindled epithelial cells",
      "sarcomatoid uterine corpus endometrioid adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A primary endometrioid adenocarcinoma of the endometrium characterized by the presence of spindled malignant epithelial cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7120,
      "label": "endometrium adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4530,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2870",
          "EFO:0005232",
          "MEDGEN:218862",
          "NCIT:C7359",
          "UMLS:C1153706"
        ],
        "synonyms": [
          "endometrioid carcinoma of endometrium",
          "adenocarcinoma of endometrium",
          "adenocarcinoma of the endometrium",
          "adenocarcinoma, endometrial, malignant",
          "endometrial adenocarcinoma",
          "endometrioid adenoma or carcinoma NOS (morphologic abnormality)",
          "endometrioid adenomas and carcinomas (morphologic abnormality)",
          "endometrium adenocarcinoma",
          "endometrial endometrioid adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An adenocarcinoma arising from the uterine body cavity. This is the most frequent malignant tumor affecting the uterine body, and is linked to estrogen therapy. Most patients present with uterine bleeding and are over age 40 at the time of diagnosis. The prognosis depends on the stage of the tumor, the depth of the uterine wall invasion, and the histologic subtype. Endometrioid adenocarcinoma is the most frequently seen morphologic variant of endometrial adenocarcinoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005461"
    },
    {
      "id": 7748,
      "label": "endometrial endometrioid adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6760
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000233",
          "MEDGEN:234467",
          "NCIT:C6287",
          "ONCOTREE:UEC",
          "UMLS:C1336905",
          "icd11.foundation:671511103"
        ],
        "synonyms": [
          "endometrial endometrioid adenocarcinoma",
          "endometrioid adenocarcinoma of endometrium",
          "endometrioid adenocarcinoma of the endometrium",
          "endometrioid carcinoma of endometrium",
          "endometrioid carcinoma of the endometrium",
          "endometrioid endomet. adenocar.",
          "endometrioid endometrial adenocarcinoma",
          "uterine corpus endometrioid adenocarcinoma",
          "uterine corpus endometrioid carcinoma",
          "uterine endometrioid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary endometrial adenocarcinoma composed of neoplastic cells that form complex glandular patterns associated with budding and branching of the neoplastic glands. The neoplastic glands resemble those of the normal endometrium and may or may not be associated with sheet-like proliferation of malignant cells. Endometrioid adenocarcinoma is the most commonly seen morphologic variant of endometrial adenocarcinoma."
      },
      "child_count": 5,
      "reference_id": "MONDO:0006192"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7120,
      "label": "endometrium adenocarcinoma"
    },
    {
      "id": 7748,
      "label": "endometrial endometrioid adenocarcinoma"
    }
  ]
}