{
  "id": 6138,
  "label": "non-gestational ovarian choriocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004322",
  "properties": {
    "xrefs": [
      "DOID:7665",
      "GARD:0023934",
      "MEDGEN:274798",
      "NCIT:C39991",
      "UMLS:C1518355"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A malignant germ cell tumor that arises from the ovary and is composed of cytotrophoblasts, syncytiotrophoblasts, and extravillous trophoblasts. The prognosis is less favorable than gestational choriocarcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5339,
      "label": "ovarian primitive germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18315
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5351",
          "GARD:0023506",
          "MEDGEN:275291",
          "NCIT:C39986",
          "UMLS:C1518727"
        ],
        "synonyms": [
          "ovarian primitive germ cell tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant tumor that arises from the ovary and is characterized by the presence of malignant germ cell components but lacks a teratoma component."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003408"
    },
    {
      "id": 5421,
      "label": "choriocarcinoma of ovary",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6924,
        18315
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5550",
          "EFO:1000413",
          "GARD:0023536",
          "MEDGEN:91089",
          "NCIT:C4515",
          "SCTID:254870004",
          "UMLS:C0346181"
        ],
        "synonyms": [
          "choriocarcinoma of ovary",
          "choriocarcinoma of the ovary",
          "germ cell choriocarcinoma of ovary",
          "germ cell choriocarcinoma of the ovary",
          "ovarian choriocarcinoma",
          "ovarian germ cell choriocarcinoma",
          "ovary choriocarcinoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A choriocarcinoma arising from the ovary. When it appears before puberty is of germ cell origin. In children and young adults signs and symptoms include precocious pseudopuberty and vaginal bleeding. Serum human chorionic gonadotropin is elevated. Germ cell derived ovarian choriocarcinoma should be differentiated from primary or metastatic gestational choriocarcinoma affecting the ovary. The prognosis of germ cell derived choriocarcinoma is less favorable and requires more aggressive chemotherapy treatment regimens compared to gestational choriocarcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003507"
    }
  ],
  "children": [
    {
      "id": 6335,
      "label": "childhood choriocarcinoma of the ovary",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5640,
        6138,
        6283,
        20015
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8336",
          "GARD:0024052",
          "MEDGEN:234135",
          "NCIT:C6549",
          "UMLS:C1332987"
        ],
        "synonyms": [
          "childhood choriocarcinoma of ovary",
          "childhood ovarian choriocarcinoma",
          "choriocarcinoma of ovary of childhood",
          "paediatric choriocarcinoma of ovary",
          "paediatric choriocarcinoma of the ovary",
          "paediatric ovarian choriocarcinoma",
          "pediatric choriocarcinoma of ovary",
          "pediatric choriocarcinoma of the ovary",
          "pediatric ovarian choriocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-gestational choriocarcinoma that arises from the ovary and occurs in children."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004535"
    }
  ],
  "roots": [
    {
      "id": 5339,
      "label": "ovarian primitive germ cell tumor"
    },
    {
      "id": 5421,
      "label": "choriocarcinoma of ovary"
    }
  ]
}