{
  "id": 6141,
  "label": "testicular thecoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004325",
  "properties": {
    "xrefs": [
      "DOID:7676",
      "GARD:0023937",
      "MEDGEN:308260",
      "NCIT:C39952",
      "UMLS:C1515299"
    ],
    "synonyms": [
      "testis thecoma",
      "thecoma of testis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A rare benign tumor that arises from the testis and is characterized by the presence of lipid-rich neoplastic spindle cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5102,
      "label": "testicular sex cord-stromal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4757",
          "GARD:0021551",
          "MEDGEN:825921",
          "NCIT:C6358",
          "Orphanet:363489",
          "SCTID:702406000",
          "UMLS:C3840076"
        ],
        "synonyms": [
          "sex cord-stromal tumor of testis",
          "sex cord-stromal tumour of testis",
          "testicular sex cord-stromal neoplasm",
          "testicular sex cord-stromal tumor",
          "testicular sex cord-stromal tumour",
          "testis sex cord-stromal tumor",
          "testis sex cord-stromal tumour",
          "sex cord-stromal neoplasm",
          "sex cord-stromal neoplasm of testis",
          "sex cord-stromal neoplasm of the testis",
          "sex cord-stromal tumor of the testis",
          "sex cord-stromal tumour of the testis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant tumor that arises from the testis. It is composed of granulosa cells, Leydig cells, Sertoli cells, and fibroblasts. Each of these cell types may constitute the only cellular component that is present in the tumor or it may be mixed with other cell types in various combinations. The prognosis can not always be predicted on histologic grounds alone. Approximately, ten percent of these tumors may metastasize. Representative examples include granulosa cell tumor, Leydig cell tumor, Sertoli cell tumor, and tumors of the thecoma-fibroma group."
      },
      "child_count": 20,
      "reference_id": "MONDO:0003125"
    },
    {
      "id": 22960,
      "label": "thecoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8600/0",
          "MEDGEN:21505",
          "MESH:D013798",
          "NCIT:C3405",
          "UMLS:C0039747"
        ],
        "synonyms": [
          "thecoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An ovarian or testicular stromal tumor characterized by the presence of lipid-rich neoplastic spindle cells. In females, uterine bleeding is the most common symptom. A minority of post-menopausal women with thecoma have an associated endometrial adenocarcinoma or rarely a malignant mixed mullerian tumor or endometrial stromal sarcoma. Rare cases with nuclear atypia and mitotic activity may metastasize. In males, thecomas are rare and they usually present as slow growing, sometimes painful masses. Metastases have not been reported."
      },
      "child_count": 2,
      "reference_id": "MONDO:0037252"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5102,
      "label": "testicular sex cord-stromal neoplasm"
    },
    {
      "id": 22960,
      "label": "thecoma"
    }
  ]
}