{
  "id": 6150,
  "label": "non-functional pancreatic neuroendocrine tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004334",
  "properties": {
    "xrefs": [
      "DOID:7698",
      "GARD:0022054",
      "ICDO:8150/3",
      "MEDGEN:277416",
      "MESH:C536126",
      "NCIT:C45837",
      "Orphanet:506075",
      "UMLS:C1334977"
    ],
    "synonyms": [
      "inactive pancreatic endocrine tumor",
      "inactive pancreatic endocrine tumour",
      "non-functional pancreatic neuroendocrine tumor",
      "non-functioning PNET",
      "non-functioning pancreatic NET",
      "non-functioning pancreatic endocrine tumor",
      "non-functioning pancreatic endocrine tumour",
      "non-functioning pancreatic neuroendocrine tumor",
      "non-functioning pancreatic neuroendocrine tumour",
      "non-functioning well differentiated pancreatic endocrine tumor",
      "non-functioning well differentiated pancreatic endocrine tumour",
      "non-functioning well-differentiated NEN of pancreas",
      "non-functioning well-differentiated neuroendocrine neoplasm of pancreas",
      "non-functioning well-differentiated pancreatic NEN",
      "non-functioning well-differentiated pancreatic neuroendocrine neoplasm",
      "non-syndromic pancreatic NET",
      "non-syndromic pancreatic neuroendocrine tumor",
      "non-syndromic pancreatic neuroendocrine tumour",
      "nonfunctional pancreatic NET",
      "nonfunctional pancreatic neuroendocrine tumor",
      "nonfunctional pancreatic neuroendocrine tumour",
      "nonsyndromic pancreatic endocrine tumor",
      "nonsyndromic pancreatic endocrine tumour",
      "nonsyndromic pancreatic neuroendocrine tumor",
      "nonsyndromic pancreatic neuroendocrine tumour",
      "non functioning pancreatic endocrine tumor",
      "non functioning pancreatic endocrine tumour",
      "non-functioning EPTs",
      "non-functioning endocrine pancreatic tumors",
      "non-functioning endocrine pancreatic tumours",
      "non-functioning neuroendocrine tumor of pancreas",
      "non-functioning neuroendocrine tumour of pancreas"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A low or intermediate grade well differentiated tumor with neuroendocrine differentiation that arises from the pancreas. It is characterized by the absence of a hormone-related clinical syndrome."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 19671,
      "label": "pancreatic neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2885,
        7431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000045",
          "GARD:0013034",
          "ICDO:8150/1",
          "MEDGEN:277875",
          "NCIT:C27720",
          "ONCOTREE:PANET",
          "Orphanet:97253",
          "UMLS:C1337011"
        ],
        "synonyms": [
          "islet cell tumor",
          "islet cell tumors - pancreas",
          "islet cell tumors of the pancreas",
          "islet cell tumour",
          "islet cell tumours - pancreas",
          "islet cell tumours of the pancreas",
          "pancreatic NET",
          "pancreatic neuroendocrine tumor",
          "well differentiated pancreatic endocrine neoplasm",
          "well differentiated pancreatic endocrine tumor",
          "well differentiated pancreatic endocrine tumour",
          "well-differentiated NEN of pancreas",
          "well-differentiated neuroendocrine neoplasm of pancreas",
          "well-differentiated pancreatic NEN",
          "well-differentiated pancreatic neuroendocrine neoplasm",
          "PANET",
          "neuroendocrine tumor of pancreas",
          "neuroendocrine tumour of pancreas",
          "pancreatic endocrine tumor",
          "pancreatic endocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma)."
      },
      "child_count": 22,
      "reference_id": "MONDO:0019954"
    },
    {
      "id": 20358,
      "label": "non-functioning endocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:458882",
          "NCIT:C94760",
          "UMLS:C2986656"
        ],
        "synonyms": [
          "endocrine-inactive tumor",
          "endocrine-inactive tumour",
          "non-functioning endocrine neoplasm",
          "nonfunctional Endocrine neoplasm",
          "nonfunctioning tumor",
          "nonfunctioning tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A hormone producing or non-producing endocrine neoplasm, not associated with a hormonal syndrome."
      },
      "child_count": 3,
      "reference_id": "MONDO:0021119"
    }
  ],
  "children": [
    {
      "id": 6190,
      "label": "pancreatic non-functioning delta cell tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4993,
        6150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7840",
          "GARD:0023968",
          "MEDGEN:235453",
          "NCIT:C28333",
          "UMLS:C1335311"
        ],
        "synonyms": [
          "non-functional pancreatic Delta cell NET",
          "non-functional pancreatic Delta cell neuroendocrine tumor",
          "non-functional pancreatic Delta cell neuroendocrine tumour",
          "non-functioning pancreatic Delta cell neoplasm",
          "non-functioning pancreatic Delta cell tumor",
          "non-functioning pancreatic Delta cell tumour",
          "nonfunctional Pancreatic Delta cell Neuroendocrine tumor",
          "nonfunctional Pancreatic Delta cell Neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A usually malignant neuroendocrine tumor arising from the delta cells of the pancreas. It is not associated with a hormonal syndrome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004377"
    }
  ],
  "roots": [
    {
      "id": 19671,
      "label": "pancreatic neuroendocrine tumor"
    },
    {
      "id": 20358,
      "label": "non-functioning endocrine neoplasm"
    }
  ]
}