{ "id": 6151, "label": "digestive system disorder", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0004335", "properties": { "xrefs": [ "DOID:77", "ICD10CM:K00-K95", "ICD9:520-579", "ICD9:V47.3", "MEDGEN:892790", "MESH:D005767", "NANDO:1100013", "NCIT:C2990", "SCTID:53619000", "UMLS:C4023588", "icd11.foundation:1256772020" ], "synonyms": [ "digestive disease", "digestive system disease", "digestive system disease or disorder", "digestive system disorder", "disease of digestive system", "disease or disorder of digestive system", "disorder of digestive system", "gastroenterological system disease", "gastroenterological system disorder", "gastrointestinal disorder", "gastrointestinal system disease", "gastrointestinal system disorder", "stomach or intestinal disorder" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A disease or disorder that involves the digestive system." }, "isLeaf": false, "isRoot": false, "child_count": 31, "parents": [ { "id": 29379, "label": "disease by body system or component", "isLeaf": false, "isRoot": false, "parents": [ 24492 ], "type_id": 0, "properties": { "definition": "A grouping class for human diseases classified by the body system or anatomical component primarily affected." }, "child_count": 19, "reference_id": "MONDO:7770006" } ], "children": [ { "id": 2884, "label": "benign digestive system neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 6151, 6887, 20434 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0050624", "MEDGEN:141680", "NCIT:C4787", "UMLS:C0497538" ], "synonyms": [ "alimentary part of gastrointestinal system benign neoplasm", "benign GI neoplasm", "benign GI system neoplasm", "benign GI system tumor", "benign GI system tumour", "benign GI tumor", "benign GI tumour", "benign digestive system tumor", "benign digestive system tumour", "benign gastrointestinal neoplasm", "benign gastrointestinal system tumor", "benign gastrointestinal system tumour", "benign gastrointestinal tumor", "benign gastrointestinal tumour", "benign neoplasm of digestive system", "benign neoplasm of gastrointestinal system", "benign neoplasm of the digestive system", "benign tumor of GI system", "benign tumor of digestive system", "benign tumor of gastrointestinal system", "benign tumor of the GI system", "benign tumor of the digestive system", "benign tumor of the gastrointestinal system", "benign tumour of GI system", "benign tumour of digestive system", "benign tumour of gastrointestinal system", "benign tumour of the GI system", "benign tumour of the digestive system", "benign tumour of the gastrointestinal system", "gastrointestinal system benign neoplasm" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A non-metastasizing neoplasm arising from any part of the digestive system." }, "child_count": 30, "reference_id": "MONDO:0000385" }, { "id": 3004, "label": "autoimmune disorder of gastrointestinal tract", "isLeaf": false, "isRoot": false, "parents": [ 6151, 8586 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0060031" ], "synonyms": [ "alimentary part of gastrointestinal system autoimmune disease", "alimentary part of gastrointestinal system hypersensitivity reaction type II disease", "autoimmune disease of alimentary part of gastrointestinal system" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005046", "name": "immune system disorder" } ], "definition": "A hypersensitivity reaction type II disease that involves the alimentary part of gastrointestinal system." }, "child_count": 14, "reference_id": "MONDO:0000588" }, { "id": 3168, "label": "gastrointestinal mucositis", "isLeaf": false, "isRoot": false, "parents": [ 6151, 20016 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0080178", "ICD9:538", "ICD9:558.9", "MEDGEN:636691", "NCIT:C3853", "SCTID:95518006", "UMLS:C0521585" ], "synonyms": [ "gastrointestinal system mucosa inflammation", "gastrointestinal system mucosaitis", "inflammation of gastrointestinal system mucosa", "mucositis" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Inflammation of the mucous membranes lining the gastrointestinal tract." }, "child_count": 4, "reference_id": "MONDO:0000888" }, { "id": 3866, "label": "diarrheal disease", "isLeaf": false, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "DOID:13250", "HP:0002014", "ICD9:009.2", "MEDGEN:713159", "MESH:D003967", "NCIT:C2987", "SCTID:128333008", "UMLS:C1290807", "icd11.foundation:116759077" ], "synonyms": [ "diarrhea", "diarrheal disease", "diarrheal disorder", "diarrhoea", "frequent stools", "loose stools", "diarrhoea of presumed infectious origin" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "The condition of having at least three loose or liquid bowel movements each day." }, "child_count": 7, "reference_id": "MONDO:0001673" }, { "id": 4455, "label": "pancreas disorder", "isLeaf": false, "isRoot": false, "parents": [ 6151, 6875 ], "type_id": 0, "properties": { "xrefs": [ "DOID:26", "EFO:0009605", "ICD10CM:K86.9", "ICD9:577.8", "ICD9:577.9", "MEDGEN:14583", "MESH:D010182", "NCIT:C26842", "SCTID:3855007", "UMLS:C0030286", "icd11.foundation:1726554290" ], "synonyms": [ "disease of pancreas", "disease or disorder of pancreas", "disorder of pancreas", "pancreas disease", "pancreas disease or disorder", "pancreatic disorder", "disease, pancreatic", "diseases, pancreatic", "pancreatic disease" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005151", "name": "endocrine system disorder" } ], "definition": "A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms." }, "child_count": 28, "reference_id": "MONDO:0002356" }, { "id": 4586, "label": "hepatobiliary disorder", "isLeaf": false, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3118", "EFO:0010284", "MEDGEN:82758", "NCIT:C3959", "UMLS:C0267792" ], "synonyms": [ "disease of hepatobiliary system", "disease or disorder of hepatobiliary system", "disorder of hepatobiliary system", "hepatobiliary disorder", "hepatobiliary system disease", "hepatobiliary system disease or disorder", "liver and biliary disease", "liver and biliary disorder", "liver and biliary system disorder" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A non-neoplastic or neoplastic disorder that affects the liver, bile ducts, and gallbladder. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and cholecystitis. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, and cholangiocarcinoma." }, "child_count": 4, "reference_id": "MONDO:0002515" }, { "id": 4587, "label": "digestive system cancer", "isLeaf": false, "isRoot": false, "parents": [ 6151, 6733, 20434 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3119", "ICD10CM:C15-C26", "ICD9:239.0", "MEDGEN:148231", "NCIT:C4890", "UMLS:C0751075" ], "synonyms": [ "GI tumor", "GI tumour", "cancer of digestive system", "digestive system cancer", "gastrointestinal system cancer", "malignant digestive system neoplasm", "malignant gastrointestinal neoplasm", "malignant gastrointestinal system neoplasm", "malignant neoplasm of digestive system" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A primary or metastatic malignant neoplasm involving any part of the digestive system." }, "child_count": 45, "reference_id": "MONDO:0002516" }, { "id": 6067, "label": "peptic ulcer disease", "isLeaf": false, "isRoot": false, "parents": [ 6151, 23253 ], "type_id": 0, "properties": { "xrefs": [ "DOID:750", "ICD9:533", "MEDGEN:45384", "MESH:D010437", "NCIT:C3318", "SCTID:13200003", "UMLS:C0030920" ], "synonyms": [ "acute peptic ulcer with haemorrhage", "acute peptic ulcer with haemorrhage and perforation", "acute peptic ulcer without haemorrhage and without perforation", "peptic ulcer" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A digestive system disease characterized by discontinuation in the inner lining of the gastrointestinal (GI) tract because of gastric acid secretion or pepsin." }, "child_count": 12, "reference_id": "MONDO:0004247" }, { "id": 6115, "label": "stomach disorder", "isLeaf": false, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "DOID:76", "EFO:0009608", "ICD9:537.89", "ICD9:537.9", "MEDGEN:21329", "MESH:D013272", "NCIT:C26886", "SCTID:29384001", "UMLS:C0038354", "icd11.foundation:1264914040" ], "synonyms": [ "disease of stomach", "disease or disorder of stomach", "disorder of stomach", "stomach disease", "stomach disease or disorder", "stomach disorder" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A disease involving the stomach." }, "child_count": 19, "reference_id": "MONDO:0004298" }, { "id": 6756, "label": "intestinal disorder", "isLeaf": false, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5295", "EFO:0009431", "ICD9:520-579", "ICD9:560-569", "ICD9:564", "ICD9:564.4", "ICD9:569", "ICD9:569.4", "ICD9:569.49", "ICD9:569.89", "ICD9:569.9", "ICD9:570-579", "ICD9:575", "MEDGEN:7130", "MESH:D007410", "NCIT:C26801", "SCTID:85919009", "UMLS:C0021831" ], "synonyms": [ "disease of intestine", "disease or disorder of intestine", "disorder of intestine", "intestinal disease", "intestinal disorder", "intestine disease", "intestine disease or disorder", "disease, intestinal", "diseases, intestinal" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A non-neoplastic or neoplastic disorder that affects the small or large intestine." }, "child_count": 58, "reference_id": "MONDO:0005020" }, { "id": 9284, "label": "Meckel diverticulum", "isLeaf": true, "isRoot": false, "parents": [ 5714, 6151 ], "type_id": 0, "properties": { "xrefs": [ "DOID:9487", "EFO:1001036", "ICD10CM:Q43.0", "ICD9:751.0", "MEDGEN:9917", "MESH:D008467", "MedDRA:10027055", "NCIT:C12264", "OMIM:155140", "SCTID:37373007", "UMLS:C0025037", "icd11.foundation:216192536", "icd11.foundation:337533229" ], "synonyms": [ "Meckel diverticulum", "Meckel's diverticulum", "persistent vitelline duct" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A congenital pouch in the distal ileum. It may cause painless rectal bleeding and bowel obstruction." }, "child_count": 0, "reference_id": "MONDO:0007955" }, { "id": 9589, "label": "Cronkhite-Canada syndrome", "isLeaf": true, "isRoot": false, "parents": [ 6151, 16103, 19138 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6225", "GARD:0004427", "MEDGEN:129128", "MESH:D044483", "MedDRA:10062907", "NANDO:1200901", "NCIT:C7035", "NORD:1017", "OMIM:175500", "Orphanet:2930", "SCTID:76304001", "UMLS:C0282207", "icd11.foundation:79007466" ], "synonyms": [ "Cronkhite-Canada syndrome", "gastric Cronkhite Canada polyposis", "gastrointestinal polyposis-ectodermal changes syndrome", "gastrointestinal polyposis-skin pigmentation-alopecia-fingernail changes syndrome", "Cronkhite-Canada disease", "polyposis skin pigmentation alopecia fingernail changes", "polyposis, skin pigmentation, alopecia, and fingernail changes" ], "categories": [ { "ref": "MONDO:0002051", "name": "integumentary system disorder" }, { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Cronkhite-Canada syndrome (CCS) is a rare gastrointestinal (GI) polyposis syndrome characterized by the association of non-hereditary GI polyposis with the cutaneous triad of alopecia, nail changes and hyperpigmentation." }, "child_count": 0, "reference_id": "MONDO:0008283" }, { "id": 10364, "label": "diverticulosis, small-intestinal", "isLeaf": true, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:341730", "MESH:C565620", "OMIM:223320", "UMLS:C1857228" ], "synonyms": [ "diverticulosis, small-intestinal" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ] }, "child_count": 0, "reference_id": "MONDO:0009119" }, { "id": 10365, "label": "diverticulosis of bowel, hernia, and retinal detachment", "isLeaf": true, "isRoot": false, "parents": [ 4370, 6151 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0003401", "MEDGEN:341729", "MESH:C565619", "OMIM:223330", "Orphanet:2464", "UMLS:C1857227" ], "synonyms": [ "diverticulosis of bowel, hernia, and retinal detachment", "marfanoid syndrome, De Silva type", "Marphanoid syndrome type De Silva" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A syndromic intestinal malformation characterized by the association of marfanoid habitus with visceral diverticula. It has been reported in four adults and two siblings from a consanguineous marriage in two different publications. Pediatric cases also presented with diaphragmatic hernia. Other connective tissue disorders with visceral diverticula have been reported previously, suggesting a relationship between these two conditions." }, "child_count": 0, "reference_id": "MONDO:0009120" }, { "id": 10416, "label": "congenital enteropathy due to enteropeptidase deficiency", "isLeaf": true, "isRoot": false, "parents": [ 5714, 6151 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0111667", "GARD:0017038", "ICD9:277.89", "MEDGEN:82802", "MESH:C562649", "NANDO:2200910", "OMIM:226200", "Orphanet:168601", "SCTID:190952002", "UMLS:C0268416" ], "synonyms": [ "congenital enterokinase deficiency", "enterokinase deficiency", "enteropeptidase deficiency" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A rare, genetic, gastroenterological disease characterized by early-onset failure to thrive, edema, hypoproteinemia, diarrhea and fat malabsorption (or steatorrhea) in the presence of very low or absent trypsin activity in duodenal fluid. Celiac disease, or other pancreatic or mucosal disorders, may be associated." }, "child_count": 0, "reference_id": "MONDO:0009173" }, { "id": 12149, "label": "hereditary mixed polyposis syndrome", "isLeaf": false, "isRoot": false, "parents": [ 6151, 16103 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0111684", "GARD:0016981", "MEDGEN:1672870", "MESH:C563365", "OMIMPS:601228", "Orphanet:157794", "UMLS:C5192681", "icd11.foundation:219068911" ], "synonyms": [ "HMPS", "hereditary mixed polyposis syndrome" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Hereditary mixed polyposis syndrome (HMPS) describes an autosomal dominantly inherited large-bowel disease characterized by the presence of a mixture of hyperplastic, atypical juvenile and adenomatous polyps that are associated with an increased risk of developing colorectal cancer if left untreated." }, "child_count": 4, "reference_id": "MONDO:0011023" }, { "id": 13002, "label": "caudal duplication", "isLeaf": true, "isRoot": false, "parents": [ 4370, 5714, 6151 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0001164", "MEDGEN:335822", "MESH:C564315", "OMIM:607864", "Orphanet:1756", "SCTID:71464000", "UMLS:C1842884", "icd11.foundation:1949559803" ], "synonyms": [ "dipygus", "split notochord syndrome", "caudal DUPLICATION anomaly" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Caudal duplication (CD) is a rare developmental anomaly in which structures derived from the embryonic cloaca and notochord are duplicated to varying extents." }, "child_count": 0, "reference_id": "MONDO:0011928" }, { "id": 15333, "label": "Moyamoya disease with early-onset achalasia", "isLeaf": true, "isRoot": false, "parents": [ 6151, 17246 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0017664", "MEDGEN:816733", "OMIM:615750", "Orphanet:401945", "SCTID:718551002", "UMLS:C3810403" ], "synonyms": [ "moyamoya 6 with achalasia", "MYMY6", "Moyamoya disease 6 with achalasia" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0004995", "name": "cardiovascular disorder" }, { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "Moyamoya disease with early-onset achalasia is an exceedingly rare autosomal recessive neurological disorder reported only in a few families so far. It is characterized by the association of early onset achalasia (manifesting in infancy) with severe intracranial angiopathy that is consistent with moyamoya angiopathy in most cases (moyamoya disease). Other variable associated manifestations include hypertension, Raynaud phenomenon, and livedo reticularis." }, "child_count": 0, "reference_id": "MONDO:0014331" }, { "id": 16339, "label": "hyperplastic polyposis syndrome", "isLeaf": false, "isRoot": false, "parents": [ 6151, 16103 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0016982", "MEDGEN:1645454", "NCIT:C165469", "Orphanet:157798", "SCTID:763536006", "UMLS:C4296896", "icd11.foundation:1344352020" ], "synonyms": [ "serrated polyposis" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Hyperplastic polyposis syndrome is a rare, genetic intestinal disease characterized by the presence of multiple (usually large) hyperplastic/serrated colorectal polyps, usually with a pancolonic distribution. Histology reveals hyperplastic polyps, sessile serrated adenomas (most common), traditional serrated adenomas or mixed polyps. It is associated with an increased personal and familial (first-degree relatives) risk of colorectal cancer." }, "child_count": 4, "reference_id": "MONDO:0015524" }, { "id": 16530, "label": "thoraco-abdominal enteric duplication", "isLeaf": true, "isRoot": false, "parents": [ 4370, 6151 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0005181", "MEDGEN:1372227", "Orphanet:1759", "SCTID:733628001", "UMLS:C4518084", "icd11.foundation:1267632171" ], "synonyms": [ "thoraco abdominal enteric duplication" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Thoraco-abdominal enteric duplication is a rare, syndromic intestinal malformation characterized by single or multiple smooth-walled, often tubular, cystic lesions, which on occasion contain ectopic gastric mucosa, located in the thorax (usually in the posterior mediastinum and to the right of the midline) and in the abdomen. Infants usually present with respiratory distress and older patients with heartburn, abdominal pain, vomiting and/or malena. Vertebral anomalies in the lower cervical spine, with CNS involvement, are frequently present and complications, such as bowel obstruction, perforation and intussusception, have also been reported." }, "child_count": 0, "reference_id": "MONDO:0015774" }, { "id": 17028, "label": "digestive duplication", "isLeaf": true, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0018684", "MEDGEN:451018", "Orphanet:238", "UMLS:C0266019" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ] }, "child_count": 0, "reference_id": "MONDO:0016531" }, { "id": 17689, "label": "juvenile polyposis syndrome", "isLeaf": false, "isRoot": false, "parents": [ 6151, 16103 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0003065", "MEDGEN:87518", "NANDO:2200916", "NCIT:C7754", "NORD:280170", "OMIM:174900", "Orphanet:2929", "SCTID:9273005", "UMLS:C0345893", "icd11.foundation:1020795563" ], "synonyms": [ "JIP", "JPS", "jPS", "juvenile gastrointestinal polyposis", "juvenile intestinal polyposis", "juvenile multiple polyps syndrome", "juvenile polyposis", "juvenile polyposis syndrome", "polyposis, juvenile intestinal", "PJI", "polyposis familial of entire gastrointestinal tract", "polyposis juvenile intestinal" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Juvenile gastrointestinal polyposis (JIP) is a rare condition characterized by the presence of juvenile hamartomatous polyps in the gastrointestinal (GI) tract." }, "child_count": 6, "reference_id": "MONDO:0017380" }, { "id": 18245, "label": "umbilical cord ulceration-intestinal atresia syndrome", "isLeaf": true, "isRoot": false, "parents": [ 4370, 6151 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0005403", "MEDGEN:419062", "MESH:C536938", "Orphanet:3405", "UMLS:C2931371" ], "synonyms": [ "umbilical cord ulcer with intestinal atresia", "umbilical cord ulceration and intestinal atresia", "umbilical ulceration and intestinal atresia" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Umbilical cord ulceration-intestinal atresia syndrome is characterized by congenital intestinal atresia, umbilical cord ulceration and severe intrauterine hemorrhage." }, "child_count": 0, "reference_id": "MONDO:0018085" }, { "id": 18413, "label": "growth retardation-mild developmental delay-chronic hepatitis syndrome", "isLeaf": true, "isRoot": false, "parents": [ 4370, 5714, 6151 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0021621", "MEDGEN:1654119", "Orphanet:391366", "UMLS:C4751595" ], "categories": [ { "ref": "MONDO:0002254", "name": "syndromic disease" }, { "ref": "MONDO:0004335", "name": "digestive system disorder" } ] }, "child_count": 0, "reference_id": "MONDO:0018317" }, { "id": 18884, "label": "common mesentery", "isLeaf": true, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:539782", "Orphanet:620", "SCTID:52159006", "UMLS:C0266235", "icd11.foundation:2101515260" ], "synonyms": [ "universal mesentery" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ] }, "child_count": 0, "reference_id": "MONDO:0018962" }, { "id": 20526, "label": "neoplasm of oropharynx", "isLeaf": false, "isRoot": false, "parents": [ 6151, 7231, 20028, 20455 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:14519", "NCIT:C3291", "SCTID:126809003", "UMLS:C0029295" ], "synonyms": [ "neoplasm of oropharynx", "neoplasm of the oropharynx", "oropharyngeal neoplasm", "oropharyngeal neoplasms", "oropharyngeal tumor", "oropharyngeal tumour", "oropharynx neoplasm", "oropharynx neoplasm (disease)", "oropharynx tumor", "oropharynx tumour", "tumor of oropharynx", "tumor of the oropharynx", "tumour of oropharynx", "tumour of the oropharynx" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005087", "name": "respiratory system disorder" }, { "ref": "MONDO:0024623", "name": "otorhinolaryngologic disease" } ], "definition": "A neoplasm (disease) that involves the oropharynx." }, "child_count": 8, "reference_id": "MONDO:0021364" }, { "id": 21327, "label": "gastrointestinal polyp", "isLeaf": false, "isRoot": false, "parents": [ 6151, 6807 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:219797", "NCIT:C35516", "UMLS:C1257915" ], "synonyms": [ "GI polyp", "gastrointestinal polyp", "gastrointestinal tract polyp" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A polypoid tumor that arises from any part of the gastrointestinal tract and protrudes into the lumen. Representative examples include adenomatous polyps, hyperplastic polyps, and hamartomatous polyps." }, "child_count": 4, "reference_id": "MONDO:0024292" }, { "id": 21456, "label": "digestive system neuroendocrine neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 6151, 19314, 20434 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0002437", "MEDGEN:232237", "MESH:C535650", "NCIT:C27721", "Orphanet:100092", "UMLS:C1333799" ], "synonyms": [ "alimentary part of gastrointestinal system NET", "alimentary part of gastrointestinal system neuroendocrine neoplasm", "alimentary part of gastrointestinal system neuroendocrine tumor", "alimentary part of gastrointestinal system neuroendocrine tumor, well differentiated, low or intermediate grade", "alimentary part of gastrointestinal system neuroendocrine tumour", "carcinoid tumor of digestive system", "carcinoid tumour of digestive system", "digestive system NET", "digestive system neuroendocrine neoplasm", "digestive system neuroendocrine tumor", "digestive system neuroendocrine tumor, well differentiated, low or intermediate grade", "digestive system neuroendocrine tumour", "gastro-enteropancreatic neuroendocrine tumor", "gastro-enteropancreatic neuroendocrine tumour", "gastroenteropancreatic endocrine tumor", "gastroenteropancreatic endocrine tumour", "gastroenteropancreatic neuroendocrine neoplasm", "gastrointestinal neuroendocrine neoplasm", "gastrointestinal system neuroendocrine neoplasm", "neuroendocrine neoplasm of alimentary part of gastrointestinal system", "neuroendocrine neoplasm of digestive system", "GEP tumors", "GEP tumours", "GEP-NEN", "GEP-NET", "carcinoid tumor", "carcinoid tumour" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005151", "name": "endocrine system disorder" } ], "definition": "A neoplasm with neuroendocrine differentiation arising from the digestive system. It includes neuroendocrine tumors (well-differentiated endocrine tumors or carcinoid tumors and well differentiated endocrine carcinomas) and neuroendocrine carcinomas (poorly differentiated neuroendocrine carcinomas, small cell carcinomas, and large cell neuroendocrine carcinomas)." }, "child_count": 21, "reference_id": "MONDO:0024503" }, { "id": 23208, "label": "digestive system infectious disorder", "isLeaf": false, "isRoot": false, "parents": [ 6151, 7200 ], "type_id": 0, "properties": { "xrefs": [ "NCIT:C35503", "SCTID:715852004" ], "synonyms": [ "digestive system infection", "gastrointestinal infection", "gastrointestinal system infection", "infection of gastrointestinal tract" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A viral, bacterial, fungal, or parasitic infectious process that affects the digestive system." }, "child_count": 44, "reference_id": "MONDO:0043424" }, { "id": 23495, "label": "upper digestive tract disorder", "isLeaf": false, "isRoot": false, "parents": [ 6151 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:712971", "SCTID:119291004", "UMLS:C1290613" ], "synonyms": [ "disease of upper digestive tract", "disease or disorder of upper digestive tract", "disorder of upper digestive tract", "disorder of upper gastrointestinal tract", "upper digestive tract disease or disorder", "upper gastrointestinal tract disease" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A disease or disorder that involves the upper digestive tract." }, "child_count": 2, "reference_id": "MONDO:0044991" }, { "id": 26280, "label": "congenital peritoneal encapsulation", "isLeaf": true, "isRoot": false, "parents": [ 6151, 20383 ], "type_id": 0, "properties": { "xrefs": [ "Orphanet:697986" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ] }, "child_count": 0, "reference_id": "MONDO:0979319" } ], "roots": [ { "id": 29379, "label": "disease by body system or component" } ] }