{
  "id": 6154,
  "label": "retinal cell cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004338",
  "properties": {
    "xrefs": [
      "DOID:771"
    ],
    "synonyms": [
      "cancer of retinal cell",
      "malignant neoplasm of retinal cell",
      "malignant retinal cell neoplasm",
      "retinal cell cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5060,
      "label": "retinal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4353,
        20441
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4645",
          "EFO:0005716",
          "ICD10CM:C69.2",
          "ICD9:190.5",
          "MEDGEN:6192",
          "MESH:D019572",
          "NCIT:C3216",
          "SCTID:363465007",
          "UMLS:C0024622",
          "icd11.foundation:1758820365"
        ],
        "synonyms": [
          "retinal tumor",
          "retinal tumour",
          "cancer of retina",
          "malignant neoplasm of retina",
          "malignant neoplasm of the retina",
          "malignant retina neoplasm",
          "malignant retina tumor",
          "malignant retina tumour",
          "malignant retinal neoplasm",
          "malignant retinal tumor",
          "malignant retinal tumour",
          "malignant tumor of retina",
          "malignant tumor of the retina",
          "malignant tumour of retina",
          "malignant tumour of the retina",
          "retina cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A malignant neoplasm involving the retina."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003072"
    },
    {
      "id": 21370,
      "label": "retinal cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20441
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:277595",
          "NCIT:C7061",
          "UMLS:C1335765"
        ],
        "synonyms": [
          "retinal cell neoplasm",
          "retinal cell tumor",
          "retinal cell tumour",
          "retinal neural cell neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A neoplasm arising from the neural retina. This category includes retinoblastoma and retinocytoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0024341"
    }
  ],
  "children": [
    {
      "id": 9679,
      "label": "retinoblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6154
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:768",
          "GARD:0007563",
          "ICDO:9510/3",
          "MEDGEN:20552",
          "MESH:D012175",
          "MedDRA:10038916",
          "NANDO:2200042",
          "NCIT:C7541",
          "ONCOTREE:RBL",
          "Orphanet:790",
          "SCTID:370967009",
          "UMLS:C0035335",
          "icd11.foundation:1855353671"
        ],
        "synonyms": [
          "RB",
          "retinoblastoma",
          "retinoblastoma, malignant",
          "RB1",
          "Rb",
          "eye cancer, retinoblastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A malignant tumor that originates in the nuclear layer of the retina. As the most common primary tumor of the eye in children, retinoblastoma is still relatively uncommon, accounting for only 1% of all malignant tumors in pediatric patients. Approximately 95% of cases are diagnosed before age 5. These tumors may be multifocal, bilateral, congenital, inherited, or acquired. Seventy-five percent of retinoblastomas are unilateral; 60% occur sporadically. A predisposition to retinoblastoma has been associated with 13q14 cytogenetic abnormalities. Patients with the inherited form also appear to be at increased risk for secondary nonocular malignancies such as osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma."
      },
      "child_count": 7,
      "reference_id": "MONDO:0008380"
    }
  ],
  "roots": [
    {
      "id": 5060,
      "label": "retinal cancer"
    },
    {
      "id": 21370,
      "label": "retinal cell neoplasm"
    }
  ]
}