{
  "id": 6156,
  "label": "mixed ductal-endocrine carcinoma of pancreas",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004340",
  "properties": {
    "xrefs": [
      "DOID:7716",
      "GARD:0027676",
      "MEDGEN:266254",
      "NCIT:C6879",
      "UMLS:C1301048"
    ],
    "synonyms": [
      "mixed ductal-endocrine carcinoma of the pancreas",
      "mixed ductal-neuroendocrine carcinoma of the pancreas",
      "mixed ductal-endocrine carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A carcinoma that arises from the pancreas showing a mixture of ductal and neuroendocrine malignant cells in both the primary tumor and in the metastatic sites."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6905,
      "label": "pancreatic ductal adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7247,
        7633
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3498",
          "DOID:3587",
          "EFO:0002517",
          "GARD:0027716",
          "ICD9:157.3",
          "MEDGEN:277490",
          "MESH:D021441",
          "NCIT:C9120",
          "UMLS:C1335302",
          "icd11.foundation:581089833"
        ],
        "synonyms": [
          "ductal adenocarcinoma of pancreas",
          "ductal adenocarcinoma of the pancreas",
          "pancreas ductal adenocarcinoma",
          "pancreas tubular adenocarcinoma",
          "pancreatic duct adenocarcinoma",
          "pancreatic ductal adenocarcinoma",
          "pancreatic ductal carcinoma",
          "pancreatic tubular adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are usually over 50 years of age. Microscopically it is characterized by the presence of glandular (ductal) differentiation and desmoplastic stroma formation. Signs and symptoms include pain, loss of weight, and jaundice. It grows rapidly and is usually detected after it has metastasized to other anatomic sites. The prognosis is usually poor."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005184"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6905,
      "label": "pancreatic ductal adenocarcinoma"
    }
  ]
}