{
  "id": 6176,
  "label": "adult spinal cord glioblastoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004363",
  "properties": {
    "xrefs": [
      "DOID:7806",
      "GARD:0023957",
      "MEDGEN:107849",
      "NCIT:C27183",
      "SCTID:276829003",
      "UMLS:C0559185"
    ],
    "synonyms": [
      "adult spinal cord glioblastoma",
      "adult spinal cord glioblastoma multiforme"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A rare spinal tumor which is highly malignant and tends to be locally invasive of surrounding neural tissue. The tumor also tends to spread throughout the neuroaxis and is often rapidly progressive. Histologically the tumors are highly cellular with nuclear and cellular pleomorphism, endothelial proliferation, mitotic figures, and, often, necrosis. This tumor has a relatively poor prognosis. Clinical features may include pain followed by rapidly progressive neurologic deficits such as extremity weakness, sensory changes, spasticity, and incontinence. (From Innocenzi et al., Clin Neurol Neurosurg 1997 Feb;99(1):1-5)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4608,
      "label": "spinal cord glioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5449,
        24071
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3185",
          "GARD:0023158",
          "MEDGEN:423646",
          "NCIT:C4534",
          "SCTID:254946004",
          "UMLS:C2937245"
        ],
        "synonyms": [
          "glial neoplasm spinal cord",
          "glial tumor of spinal cord",
          "glial tumour of spinal cord",
          "malignant glioma of spinal cord",
          "spinal cord glial neoplasm",
          "spinal cord glial tumor",
          "spinal cord glial tumour",
          "spinal cord glioma",
          "spinal cord malignant glioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm that arises from glial cells in the spinal cord. Representative examples include astrocytoma, oligodendroglioma, and ependymoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002542"
    },
    {
      "id": 20099,
      "label": "adult glioblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6136,
        18320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025213",
          "MEDGEN:124527",
          "NANDO:2200087",
          "NCIT:C9094",
          "UMLS:C0278878"
        ],
        "synonyms": [
          "glioblastoma",
          "adult glioblastoma",
          "adult glioblastoma multiforme",
          "grade IV adult astrocytic neoplasm",
          "grade IV adult astrocytic tumor",
          "grade IV adult astrocytic tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0020690"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4608,
      "label": "spinal cord glioma"
    },
    {
      "id": 20099,
      "label": "adult glioblastoma"
    }
  ]
}