{
  "id": 6205,
  "label": "maxillary sinus squamous cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004394",
  "properties": {
    "xrefs": [
      "DOID:7910",
      "GARD:0023975",
      "MEDGEN:277348",
      "NCIT:C6064",
      "SCTID:707354003",
      "UMLS:C1334647",
      "icd11.foundation:1253589818"
    ],
    "synonyms": [
      "epidermoid carcinoma of maxillary antrum",
      "epidermoid carcinoma of maxillary sinus",
      "epidermoid carcinoma of maxillofacial sinus",
      "epidermoid carcinoma of the maxillary antrum",
      "epidermoid carcinoma of the maxillary sinus",
      "maxillary antrum epidermoid carcinoma",
      "maxillary antrum squamous cell carcinoma",
      "maxillary sinus epidermoid carcinoma",
      "maxillary sinus squamous cell carcinoma",
      "maxillofacial sinus epidermoid carcinoma",
      "maxillofacial sinus squamous cell carcinoma",
      "squamous cell carcinoma of maxillary antrum",
      "squamous cell carcinoma of maxillary sinus",
      "squamous cell carcinoma of maxillofacial sinus",
      "squamous cell carcinoma of the maxillary antrum",
      "squamous cell carcinoma of the maxillary sinus",
      "squamous cell carcinoma of the maxillofacial sinus"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "A squamous cell carcinoma that arises from the mucosal epithelial surface of the maxillary sinus. Patients may present with nasal fullness, obstruction, and/or epistaxis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3934,
      "label": "maxillary sinus carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2879,
        4264,
        7738,
        8294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1357",
          "GARD:0023002",
          "ICD9:160.2",
          "MEDGEN:196632",
          "NCIT:C3540",
          "NCIT:C9332",
          "SCTID:363425008",
          "UMLS:C0740487"
        ],
        "synonyms": [
          "cancer of maxillary sinus",
          "carcinoma of maxillary sinus",
          "malignant maxillary sinus neoplasm",
          "malignant maxillary sinus tumor",
          "malignant maxillary sinus tumour",
          "malignant neoplasm of maxillary sinus",
          "malignant neoplasm of the maxillary sinus",
          "malignant tumor of maxillary sinus",
          "malignant tumor of the maxillary sinus",
          "malignant tumour of maxillary sinus",
          "malignant tumour of the maxillary sinus",
          "maxillary sinus cancer",
          "maxillary sinus carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A carcinoma that arises from the maxillary sinus. Representative examples include squamous cell carcinoma, adenocarcinoma, and adenoid cystic carcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0001748"
    },
    {
      "id": 6701,
      "label": "oral cavity squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23401,
        23483
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050866",
          "EFO:0000199",
          "GARD:0017932",
          "MEDGEN:108436",
          "NCIT:C4833",
          "ONCOTREE:OCSC",
          "Orphanet:502363",
          "SCTID:307502000",
          "UMLS:C0585362"
        ],
        "synonyms": [
          "mouth scc",
          "mouth squamous cell carcinoma",
          "oral cavity scc",
          "oral cavity squamous cell cancer",
          "oral cavity squamous cell carcinoma",
          "scc of mouth",
          "scc of oral cavity",
          "scc of the mouth",
          "scc of the oral cavity",
          "squamous cell carcinoma of mouth",
          "squamous cell carcinoma of oral cavity",
          "squamous cell carcinoma of the mouth",
          "squamous cell carcinoma of the oral cavity",
          "OCSC",
          "oral squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A squamous cell carcinoma arising from the oral cavity. It affects predominantly adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with signs and symptoms of locally advanced disease including mucosal ulceration, pain, difficulty with speaking, chewing, and swallowing, bleeding, weight loss, and neck swelling. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status."
      },
      "child_count": 14,
      "reference_id": "MONDO:0004958"
    },
    {
      "id": 23399,
      "label": "paranasal sinus squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2879,
        2965,
        11332
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2442",
          "GARD:0017927",
          "MEDGEN:79105",
          "NCIT:C8193",
          "Orphanet:500464",
          "UMLS:C0280334"
        ],
        "synonyms": [
          "epidermoid carcinoma of paranasal sinus",
          "epidermoid carcinoma of the paranasal sinus",
          "paranasal sinus epidermoid carcinoma",
          "paranasal sinus squamous cell carcinoma",
          "squamous cell carcinoma of paranasal sinus",
          "squamous cell carcinoma of the nasal cavity and sinuses",
          "squamous cell carcinoma of the paranasal sinus",
          "squamous cell carcinoma of the nasal cavity and paranasal sinuses"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A squamous cell carcinoma that arises from the mucosal epithelial surface of the ethmoid, frontal, maxillary, or sphenoid sinus. Patients may present with nasal fullness, obstruction, and/or epistaxis."
      },
      "child_count": 12,
      "reference_id": "MONDO:0044705"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3934,
      "label": "maxillary sinus carcinoma"
    },
    {
      "id": 6701,
      "label": "oral cavity squamous cell carcinoma"
    },
    {
      "id": 23399,
      "label": "paranasal sinus squamous cell carcinoma"
    }
  ]
}