{
  "id": 6221,
  "label": "malignant spiradenoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004412",
  "properties": {
    "xrefs": [
      "DOID:7960",
      "GARD:0010466",
      "ICDO:8403/3",
      "MEDGEN:266097",
      "NCIT:C5117",
      "SCTID:403942003",
      "UMLS:C1266063"
    ],
    "synonyms": [
      "Spiradenocarcinoma",
      "malignant eccrine spiradenoma",
      "malignant eccrine spiradenoma (morphologic abnormality)",
      "malignant spiradenoma",
      "spiradenoma, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A very rare, aggressive carcinoma of the sweat glands arising from malignant transformation of a long standing spiradenoma. It usually grows in the upper extremities, lower extremities, trunk, and head and neck. It has the tendency to recur and metastasize most often to the lymph nodes, bones, and lungs."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 21295,
      "label": "eccrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7162,
        7178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4920",
          "ICDO:8413/3",
          "MEDGEN:690083",
          "NCIT:C27255",
          "SCTID:400173004",
          "UMLS:C1266066"
        ],
        "synonyms": [
          "carcinoma of eccrine sweat gland",
          "carcinoma, eccrine gland, malignant",
          "eccrine adenocarcinoma",
          "eccrine adenocarcinoma (morphologic abnormality)",
          "eccrine carcinoma",
          "eccrine carcinoma of skin",
          "eccrine sweat gland adenocarcinoma",
          "eccrine sweat gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An adenocarcinoma with eccrine differentiation arising from the sweat glands. It includes the following subtypes: ductal eccrine adenocarcinoma, papillary eccrine carcinoma, and eccrine porocarcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0024240"
    },
    {
      "id": 21606,
      "label": "secondary neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1851572",
          "NCIT:C36255",
          "UMLS:C5848363"
        ],
        "synonyms": [
          "secondary neoplasm",
          "secondary tumor",
          "secondary tumour"
        ],
        "definition": "A neoplasm that arises from a pre-existing lower grade lesion, or as a result of a primary lesion that has spread to secondary sites, or due to a complication of a cancer treatment."
      },
      "child_count": 5,
      "reference_id": "MONDO:0024882"
    }
  ],
  "children": [
    {
      "id": 6229,
      "label": "breast malignant eccrine spiradenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6221,
        6729
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7983",
          "GARD:0027680",
          "MEDGEN:277329",
          "NCIT:C5180",
          "UMLS:C1334565"
        ],
        "synonyms": [
          "breast malignant spiradenoma",
          "malignant breast eccrine spiradenoma",
          "malignant eccrine spiradenoma of breast",
          "malignant eccrine spiradenoma of the breast",
          "malignant spiradenoma of breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A rare tumor characterized by malignant transformation of an eccrine spiradenoma of the breast."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004420"
    }
  ],
  "roots": [
    {
      "id": 21295,
      "label": "eccrine carcinoma"
    },
    {
      "id": 21606,
      "label": "secondary neoplasm"
    }
  ]
}