{
  "id": 6241,
  "label": "papillary carcinoma of the penis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004433",
  "properties": {
    "xrefs": [
      "DOID:8013",
      "GARD:0024002",
      "MEDGEN:235455",
      "NCIT:C6983",
      "UMLS:C1335322"
    ],
    "synonyms": [
      "papillary carcinoma of penis",
      "papillary carcinoma of the penis",
      "papillary penile carcinoma",
      "papillary penile squamous carcinoma",
      "papillary squamous carcinoma of penis",
      "papillary squamous carcinoma of the penis",
      "penis papillary carcinoma",
      "squamous carcinoma of penis, papillary type",
      "squamous carcinoma of the penis, papillary type"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A squamous cell carcinoma that arises from the penis and is characterized by the presence of a papillary growth pattern."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4983,
      "label": "papillary squamous carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        8000
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4385",
          "ICDO:8052/3",
          "MEDGEN:83115",
          "NCIT:C4102",
          "UMLS:C0334244"
        ],
        "synonyms": [
          "papillary epidermoid carcinoma",
          "papillary epidermoid cell carcinoma",
          "papillary squamous carcinoma",
          "papillary squamous cell carcinoma"
        ],
        "definition": "A well differentiated squamous cell carcinoma characterized by a papillary, exophytic growth pattern and hyperkeratosis. The most commonly affected anatomic sites are the larynx, penis, cervix, vagina, and vulva."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002979"
    },
    {
      "id": 18435,
      "label": "squamous cell carcinoma of penis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7886
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5518",
          "GARD:0021639",
          "MEDGEN:116057",
          "NCIT:C7729",
          "ONCOTREE:PSCC",
          "Orphanet:398058",
          "SCTID:403468003",
          "UMLS:C0238348",
          "icd11.foundation:186592209"
        ],
        "synonyms": [
          "epidermoid carcinoma of penis",
          "epidermoid carcinoma of the penis",
          "epidermoid cell carcinoma of penis",
          "epidermoid cell carcinoma of the penis",
          "penile epidermoid carcinoma",
          "penile epidermoid cell carcinoma",
          "penile squamous car.(epidermoid)",
          "penile squamous carcinoma (epidermoid)",
          "penile squamous cell cancer",
          "penile squamous cell carcinoma",
          "penis squamous cell carcinoma",
          "squamous cell carcinoma of penis",
          "squamous cell carcinoma of the penis",
          "PSCC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma arising from the penis. It occurs chiefly in the squamous epithelium of the glans, coronal sulcus, and foreskin. Etiologic factors include phimosis, lichen sclerosus, smoking, ultraviolet irradiation, history of warts or condylomas, and lack of circumcision. Human papilloma virus is present in a subset of penile squamous cell carcinomas. Patients may present with an exophytic or flat ulcerative mass in the glans or a large primary tumor with inguinal nodal and skin metastases. Morphologic variants include the basaloid carcinoma, warty (condylomatous) carcinoma, verrucous carcinoma, and sarcomatoid (spindle cell) carcinoma. (WHO, 2004)"
      },
      "child_count": 10,
      "reference_id": "MONDO:0018352"
    }
  ],
  "children": [
    {
      "id": 5581,
      "label": "penis verrucous carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6241,
        7597
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5908",
          "GARD:0023621",
          "MEDGEN:234477",
          "NCIT:C6982",
          "ONCOTREE:VPSCC",
          "UMLS:C1336955"
        ],
        "synonyms": [
          "penis verrucous carcinoma",
          "squamous carcinoma of penis, verrucous type",
          "squamous carcinoma of the penis, verrucous type",
          "verrucous carcinoma of penis",
          "verrucous carcinoma of the penis",
          "verrucous penile carcinoma",
          "verrucous penile squamous carcinoma",
          "verrucous squamous carcinoma of penis",
          "verrucous squamous carcinoma of the penis",
          "verrucous penile squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A slow growing, locally recurring, very well differentiated papillary squamous cell carcinoma that arises from the penis. It is characterized by the presence of acanthosis and hyperkeratosis. The neoplastic infiltrate extends into the underlying stroma with a pushing border. Koilocytotic atypia is not present."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003698"
    },
    {
      "id": 20063,
      "label": "warty carcinoma of the penis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6241,
        20070
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025197",
          "MEDGEN:234997",
          "NCIT:C6981",
          "ONCOTREE:WPSCC",
          "UMLS:C1337009"
        ],
        "synonyms": [
          "condylomatous carcinoma of penis",
          "condylomatous carcinoma of the penis",
          "condylomatous penile squamous cell carcinoma",
          "condylomatous squamous cell carcinoma of penis",
          "condylomatous squamous cell carcinoma of the penis",
          "squamous cell carcinoma of penis, condylomatous type",
          "squamous cell carcinoma of penis, warty type",
          "squamous cell carcinoma of the penis, condylomatous type",
          "squamous cell carcinoma of the penis, warty type",
          "warty carcinoma of penis",
          "warty carcinoma of the penis",
          "warty penile squamous cell carcinoma",
          "warty squamous cell carcinoma of penis",
          "warty squamous cell carcinoma of the penis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma that arises from the penis. It is characterized by a papillary growth pattern, hyperkeratosis and parakeratosis. Koilocytotic atypia is present. Human papillomavirus types 16 and 6 have been identified in some cases."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020649"
    }
  ],
  "roots": [
    {
      "id": 4983,
      "label": "papillary squamous carcinoma"
    },
    {
      "id": 18435,
      "label": "squamous cell carcinoma of penis"
    }
  ]
}