{
  "id": 6258,
  "label": "childhood central nervous system germinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004452",
  "properties": {
    "xrefs": [
      "DOID:8078",
      "GARD:0024013",
      "MEDGEN:272460",
      "NCIT:C27406",
      "UMLS:C1332953"
    ],
    "synonyms": [
      "Central nervous system germinoma",
      "central nervous system germinoma of childhood",
      "paediatric central nervous system germinoma",
      "pediatric central nervous system germinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A germinoma arising from the central nervous system during childhood."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4998,
      "label": "central nervous system germinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        4999,
        16619
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4438",
          "GARD:0023320",
          "MEDGEN:232242",
          "NCIT:C7009",
          "UMLS:C1333813"
        ],
        "synonyms": [
          "central nervous system germinoma",
          "central nervous system germinoma (disease)",
          "germinoma of CNS",
          "germinoma of central nervous system",
          "germinoma of the CNS",
          "germinoma of the central nervous system",
          "intracranial germinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant germ cell tumor arising from the central nervous system. It is composed of uniform cells resembling primitive germ cells. These cells have large, vesicular nuclei, prominent nucleoli and a clear, glycogen-rich cytoplasm. Additional features are lymphoid or lymphoplasmacytic infiltrates and, less frequently, scattered syncytiotrophoblastic giant cells. (Adapted from WHO)"
      },
      "child_count": 9,
      "reference_id": "MONDO:0002999"
    },
    {
      "id": 5630,
      "label": "childhood central nervous system germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4999,
        5631
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6052",
          "GARD:0023650",
          "MEDGEN:124505",
          "NCIT:C6205",
          "UMLS:C0278754"
        ],
        "synonyms": [
          "central nervous system germ cell tumor",
          "central nervous system germ cell tumour",
          "central nervous system childhood germ cell tumor",
          "central nervous system paediatric germ cell cancer",
          "central nervous system pediatric germ cell cancer",
          "childhood CNS germ cell neoplasm",
          "childhood CNS germ cell tumor",
          "childhood CNS germ cell tumour",
          "childhood central nervous system germ cell neoplasm",
          "childhood central nervous system germ cell tumor",
          "childhood germ cell neoplasm of CNS",
          "childhood germ cell neoplasm of central nervous system",
          "childhood germ cell neoplasm of the CNS",
          "childhood germ cell neoplasm of the central nervous system",
          "childhood germ cell tumor of CNS",
          "childhood germ cell tumor of central nervous system",
          "childhood germ cell tumor of the CNS",
          "childhood germ cell tumor of the central nervous system",
          "childhood germ cell tumour of CNS",
          "childhood germ cell tumour of central nervous system",
          "childhood germ cell tumour of the CNS",
          "childhood germ cell tumour of the central nervous system",
          "paediatric CNS germ cell neoplasm",
          "paediatric CNS germ cell tumour",
          "paediatric central nervous system germ cell neoplasm",
          "paediatric central nervous system germ cell tumour",
          "paediatric germ cell neoplasm of central nervous system",
          "paediatric germ cell neoplasm of the CNS",
          "paediatric germ cell neoplasm of the central nervous system",
          "paediatric germ cell tumour of CNS",
          "paediatric germ cell tumour of central nervous system",
          "paediatric germ cell tumour of the CNS",
          "paediatric germ cell tumour of the central nervous system",
          "pediatric CNS germ cell neoplasm",
          "pediatric CNS germ cell tumor",
          "pediatric central nervous system germ cell neoplasm",
          "pediatric central nervous system germ cell tumor",
          "pediatric germ cell neoplasm of CNS",
          "pediatric germ cell neoplasm of central nervous system",
          "pediatric germ cell neoplasm of the CNS",
          "pediatric germ cell neoplasm of the central nervous system",
          "pediatric germ cell tumor of CNS",
          "pediatric germ cell tumor of central nervous system",
          "pediatric germ cell tumor of the CNS",
          "pediatric germ cell tumor of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A germ cell tumor of the central nervous system occurring in children."
      },
      "child_count": 16,
      "reference_id": "MONDO:0003750"
    },
    {
      "id": 6283,
      "label": "malignant childhood germ cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5631,
        7832,
        8005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8149",
          "GARD:0024027",
          "MEDGEN:233150",
          "NCIT:C6541",
          "UMLS:C1334574"
        ],
        "synonyms": [
          "malignant childhood germ cell neoplasm",
          "malignant paediatric germ cell tumour",
          "malignant pediatric germ cell tumor",
          "malignant childhood germ cell tumor",
          "malignant childhood germ cell tumour",
          "malignant paediatric germ cell neoplasm",
          "malignant pediatric germ cell neoplasm"
        ],
        "definition": "A malignant germ cell tumor that occurs during childhood."
      },
      "child_count": 36,
      "reference_id": "MONDO:0004479"
    }
  ],
  "children": [
    {
      "id": 6039,
      "label": "childhood brain germinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4334,
        6258
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7429",
          "GARD:0023882",
          "MEDGEN:272458",
          "NCIT:C6207",
          "UMLS:C1332948"
        ],
        "synonyms": [
          "brain germinoma of childhood",
          "germinoma of childhood brain",
          "germinoma of paediatric brain",
          "germinoma of pediatric brain",
          "germinoma of the childhood brain",
          "germinoma of the paediatric brain",
          "germinoma of the pediatric brain",
          "paediatric brain germ cell cancer",
          "paediatric brain germinoma",
          "pediatric brain germ cell cancer",
          "pediatric brain germinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A germinoma arising from the brain during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004217"
    }
  ],
  "roots": [
    {
      "id": 4998,
      "label": "central nervous system germinoma"
    },
    {
      "id": 5630,
      "label": "childhood central nervous system germ cell tumor"
    },
    {
      "id": 6283,
      "label": "malignant childhood germ cell neoplasm"
    }
  ]
}