{
  "id": 6298,
  "label": "myocarditis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004496",
  "properties": {
    "xrefs": [
      "DOID:820",
      "EFO:0009609",
      "GARD:0007137",
      "ICD10CM:I40",
      "ICD9:429.0",
      "MEDGEN:44553",
      "MESH:D009205",
      "NCIT:C34831",
      "NORD:1882",
      "SCTID:50920009",
      "UMLS:C0027059",
      "icd11.foundation:1018829714"
    ],
    "synonyms": [
      "inflammation of myocardium",
      "myocardial inflammation (finding)",
      "myocardium inflammation"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Myocarditis is a condition that is characterized by inflammation of the heart muscle (myocardium). Some affected people have no noticeable symptoms of the condition. When present, signs and symptoms may include chest pain, abnormal heartbeat, shortness of breath, fatigue, signs of infection (i.e. fever, headache, sore throat, diarrhea), and leg swelling. Myocarditis can be caused by a variety of factors including infections (viral, bacterial, parasitic, and fungal), allergic reactions to certain medications, and exposure to certain chemicals. It can also be associated with other inflammatory conditions such as lupus, Wegener's granulomatosis, giant cell arteritis and Takayasu's arteritis. Most cases occur sporadically in people with no family history of the condition. Treatment aims to address the underlying cause of the condition. Medications and rarely, a heart transplant may be needed if the heart muscle becomes weak."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 3007,
      "label": "intrinsic cardiomyopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6735
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060036",
          "GARD:0022809"
        ],
        "synonyms": [
          "intrinsic cardiomyopathy",
          "primary cardiomyopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A cardiomyopathy that is due to abnormalities in heart muscle cells."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000591"
    },
    {
      "id": 21547,
      "label": "inflammation of heart layer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:429.89",
          "MEDGEN:163689",
          "SCTID:399617002",
          "UMLS:C0869523"
        ],
        "synonyms": [
          "carditis",
          "heart layer inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An inflammatory disease involving a pathogenic inflammatory response in the heart layer."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024636"
    },
    {
      "id": 21552,
      "label": "myocardial disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:469033",
          "NCIT:C35544",
          "SCTID:57809008",
          "UMLS:C3241958"
        ],
        "synonyms": [
          "disease of myocardium",
          "disease or disorder of myocardium",
          "disorder of myocardium",
          "myocardial disease",
          "myocardial disorder",
          "myocardium disease",
          "myocardium disease or disorder",
          "disorder of heart muscle"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disorder that affects the muscle tissue of the heart. Representative examples include myocardial infarction, myocarditis, and cardiomyopathy."
      },
      "child_count": 5,
      "reference_id": "MONDO:0024643"
    }
  ],
  "children": [
    {
      "id": 3361,
      "label": "Fiedler's myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6298
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10778",
          "GARD:0022882",
          "ICD10CM:I40.1",
          "ICD9:422.91",
          "MEDGEN:510047",
          "SCTID:266238009",
          "UMLS:C0155689"
        ],
        "synonyms": [
          "idiopathic myocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001113"
    },
    {
      "id": 3362,
      "label": "bacterial myocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6298
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10779",
          "GARD:0022883",
          "ICD10CM:I40.0",
          "ICD9:422.92",
          "MEDGEN:730492",
          "NCIT:C128380",
          "SCTID:64043005",
          "UMLS:C1384588",
          "icd11.foundation:900037931"
        ],
        "synonyms": [
          "septic myocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Myocarditis that is caused by an infection with a bacterial agent."
      },
      "child_count": 1,
      "reference_id": "MONDO:0001114"
    },
    {
      "id": 4841,
      "label": "acute myocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6298,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3951",
          "GARD:0023253",
          "ICD10WHO:I40",
          "ICD9:422",
          "ICD9:422.90",
          "ICD9:422.99",
          "MEDGEN:102339",
          "NCIT:C35206",
          "SCTID:46701001",
          "UMLS:C0155686"
        ],
        "synonyms": [
          "myocarditis, acute"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "The sudden onset of inflammation of heart muscle with myocellular necrosis; this is generally secondary to an infectious cause, and patients often have a recent history of a flu-like illness."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002815"
    },
    {
      "id": 6288,
      "label": "interstitial myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6298
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:817",
          "GARD:0024031",
          "MEDGEN:44554",
          "NCIT:C35786",
          "SCTID:37925008",
          "UMLS:C0027060"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Inflammation of the heart characterized by infiltration of the interstitial tissues by inflammatory cells, histiocytes, and the formation of granulomas. Giant cells are often present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004485"
    },
    {
      "id": 6378,
      "label": "rheumatic myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6298,
        8383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8481",
          "GARD:0024072",
          "ICD10CM:I09.0",
          "ICD9:391.9",
          "ICD9:398.0",
          "MEDGEN:56370",
          "NCIT:C35202",
          "SCTID:195136004",
          "UMLS:C0155557",
          "icd11.foundation:1177212968"
        ],
        "synonyms": [
          "acute rheumatic myocarditis",
          "acute rheumatic myocarditis (disorder) [ambiguous]",
          "rheumatic myocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Inflammation of the myocardium in acute rheumatic heart disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004582"
    },
    {
      "id": 20879,
      "label": "autoimmune myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6298,
        22008
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080767",
          "GARD:0009519",
          "MEDGEN:299070",
          "UMLS:C1608389"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Autoimmune myocarditis is an autoimmune disease that affects the heart. The condition is characterized by inflammation of the heart muscle (myocardium). Some people with autoimmune myocarditis have no noticeable symptoms of the condition. When present, signs and symptoms may include chest pain, abnormal heartbeat, shortness of breath, fatigue, signs of infection (i.e. fever, headache, sore throat, diarrhea), and leg swelling. The exact underlying cause of the condition is currently unknown; however, autoimmune conditions, in general, occur when the immune system mistakenly attacks healthy tissue. Treatment is based on the signs and symptoms present in each person. In some cases, medications that suppress the immune system may be recommended."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022519"
    },
    {
      "id": 21160,
      "label": "viral myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6298,
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025370",
          "ICD10CM:B33.22",
          "MEDGEN:547112",
          "NCIT:C128381",
          "SCTID:89141000",
          "UMLS:C0276138",
          "icd11.foundation:231270764"
        ],
        "synonyms": [
          "viral myocarditis",
          "Viral Myocarditis",
          "Viral myocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Myocarditis that is caused by an infection with a viral agent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0023161"
    }
  ],
  "roots": [
    {
      "id": 3007,
      "label": "intrinsic cardiomyopathy"
    },
    {
      "id": 21547,
      "label": "inflammation of heart layer"
    },
    {
      "id": 21552,
      "label": "myocardial disorder"
    }
  ]
}