{
  "id": 6378,
  "label": "rheumatic myocarditis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004582",
  "properties": {
    "xrefs": [
      "DOID:8481",
      "GARD:0024072",
      "ICD10CM:I09.0",
      "ICD9:391.9",
      "ICD9:398.0",
      "MEDGEN:56370",
      "NCIT:C35202",
      "SCTID:195136004",
      "UMLS:C0155557",
      "icd11.foundation:1177212968"
    ],
    "synonyms": [
      "acute rheumatic myocarditis",
      "acute rheumatic myocarditis (disorder) [ambiguous]",
      "rheumatic myocarditis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Inflammation of the myocardium in acute rheumatic heart disease."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6298,
      "label": "myocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3007,
        21547,
        21552
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:820",
          "EFO:0009609",
          "GARD:0007137",
          "ICD10CM:I40",
          "ICD9:429.0",
          "MEDGEN:44553",
          "MESH:D009205",
          "NCIT:C34831",
          "NORD:1882",
          "SCTID:50920009",
          "UMLS:C0027059",
          "icd11.foundation:1018829714"
        ],
        "synonyms": [
          "inflammation of myocardium",
          "myocardial inflammation (finding)",
          "myocardium inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Myocarditis is a condition that is characterized by inflammation of the heart muscle (myocardium). Some affected people have no noticeable symptoms of the condition. When present, signs and symptoms may include chest pain, abnormal heartbeat, shortness of breath, fatigue, signs of infection (i.e. fever, headache, sore throat, diarrhea), and leg swelling. Myocarditis can be caused by a variety of factors including infections (viral, bacterial, parasitic, and fungal), allergic reactions to certain medications, and exposure to certain chemicals. It can also be associated with other inflammatory conditions such as lupus, Wegener's granulomatosis, giant cell arteritis and Takayasu's arteritis. Most cases occur sporadically in people with no family history of the condition. Treatment aims to address the underlying cause of the condition. Medications and rarely, a heart transplant may be needed if the heart muscle becomes weak."
      },
      "child_count": 21,
      "reference_id": "MONDO:0004496"
    },
    {
      "id": 8383,
      "label": "rheumatic heart disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050827",
          "EFO:1001161",
          "ICD9:398.90",
          "ICD9:398.99",
          "MEDGEN:20565",
          "MESH:D012214",
          "MedDRA:10062110",
          "NCIT:C34882",
          "SCTID:23685000",
          "UMLS:C0035439",
          "icd11.foundation:291726710"
        ],
        "synonyms": [
          "RHD",
          "disease, rheumatic heart",
          "heart disease, rheumatic",
          "rheumatic carditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An autoinflammatory condition following an infection with Group A Beta Hemolytic Streptococcus (GABHS), in which the heart is attacked by antibodies formed in reaction to a recent GABHS infection. Chief anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords, all of which can result in valvular dysfunction."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006955"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6298,
      "label": "myocarditis"
    },
    {
      "id": 8383,
      "label": "rheumatic heart disease"
    }
  ]
}