{
  "id": 6433,
  "label": "in situ carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004647",
  "properties": {
    "xrefs": [
      "DOID:8719",
      "ICD9:230-234",
      "ICD9:234.8",
      "ICD9:234.9",
      "ICDO:8010/2",
      "MEDGEN:763",
      "MESH:D002278",
      "NCIT:C2917",
      "SCTID:109355002",
      "UMLS:C0007099"
    ],
    "synonyms": [
      "CIS",
      "carcinoma in situ",
      "carcinoma, in situ, malignant",
      "epithelial tumor, in situ, malignant",
      "intraepithelial carcinoma",
      "non-invasive carcinoma",
      "stage 0 disease"
    ],
    "definition": "A malignant epithelial neoplasm which is confined to the epithelial layer without evidence of further tissue invasion."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 21,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    },
    {
      "id": 20078,
      "label": "high grade malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:234350",
          "NCIT:C36046",
          "UMLS:C1334017"
        ],
        "synonyms": [
          "high grade malignant neoplasm"
        ]
      },
      "child_count": 3,
      "reference_id": "MONDO:0020665"
    },
    {
      "id": 20315,
      "label": "precancerous condition",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23519
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:19442",
          "MESH:D011230",
          "NCIT:C3341",
          "UMLS:C0032927"
        ],
        "synonyms": [
          "precancerous condition",
          "precancerous state",
          "premalignant condition",
          "premalignant state"
        ],
        "definition": "A pathological process with signs indicating it may become cancerous. Representative examples include leukoplakia, dysplastic nevus, actinic keratosis, xeroderma pigmentosum, and intraepithelial neoplasia."
      },
      "child_count": 8,
      "reference_id": "MONDO:0021074"
    }
  ],
  "children": [
    {
      "id": 2870,
      "label": "oral cavity carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        23483
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050610",
          "GARD:0027525",
          "MEDGEN:138076",
          "NCIT:C4587",
          "SCTID:92660005",
          "UMLS:C0347073",
          "icd11.foundation:1389868484"
        ],
        "synonyms": [
          "carcinoma in situ of mouth",
          "carcinoma in situ of oral cavity",
          "carcinoma in situ of the mouth",
          "carcinoma in situ of the oral cavity",
          "mouth carcinoma in situ",
          "oral cavity in situ carcinoma",
          "stage 0 carcinoma of mouth",
          "stage 0 carcinoma of oral cavity",
          "stage 0 carcinoma of the mouth",
          "stage 0 carcinoma of the oral cavity",
          "stage 0 mouth carcinoma",
          "stage 0 oral cavity cancer",
          "stage 0 oral cavity cancer aJCC v6",
          "stage 0 oral cavity cancer aJCC v6 and v7",
          "stage 0 oral cavity cancer aJCC v7",
          "stage 0 oral cavity carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the oral cavity."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000371"
    },
    {
      "id": 2871,
      "label": "pharynx carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        20516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050611",
          "ICD10CM:D00.08",
          "MEDGEN:83851",
          "NCIT:C4942",
          "SCTID:92681005",
          "UMLS:C0347098",
          "icd11.foundation:1272356737"
        ],
        "synonyms": [
          "carcinoma in situ of pharynx",
          "carcinoma in situ of the pharynx",
          "pharyngeal cancer stage 0",
          "pharyngeal carcinoma in situ",
          "pharynx carcinoma in situ",
          "pharynx in situ carcinoma",
          "stage 0 carcinoma of pharynx",
          "stage 0 carcinoma of the pharynx",
          "stage 0 pharyngeal cancer",
          "stage 0 pharyngeal carcinoma",
          "stage 0 pharyngeal throat cancer",
          "stage 0 pharynx carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Stage 0 carcinoma of the pharynx according to the American Joint Committee on Cancer, 6th, 7th, and 8th editions."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000372"
    },
    {
      "id": 2872,
      "label": "gall bladder carcinoma in situ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5174,
        6433
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050612",
          "GARD:0022758",
          "MEDGEN:87523",
          "NCIT:C4439",
          "UMLS:C0345911"
        ],
        "synonyms": [
          "carcinoma in situ of gall bladder",
          "gall bladder in situ carcinoma",
          "stage 0 gall bladder carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma in situ involving a gall bladder."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000373"
    },
    {
      "id": 5172,
      "label": "adenocarcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4943",
          "ICDO:8140/2",
          "MEDGEN:87203",
          "MESH:D065311",
          "NCIT:C4123",
          "ONCOTREE:AIS",
          "UMLS:C0334276"
        ],
        "synonyms": [
          "adenocarcinoma in situ",
          "AIS"
        ],
        "definition": "A lesion in which the normally situated glands are partially or completely replaced by atypical cells with malignant characteristics."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003218"
    },
    {
      "id": 5663,
      "label": "nasal cavity carcinoma in situ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5168,
        6433
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6148",
          "ICD9:231.8",
          "MEDGEN:138077",
          "NCIT:C4589",
          "SCTID:92663007",
          "UMLS:C0347095"
        ],
        "synonyms": [
          "carcinoma in situ of nasal cavity",
          "carcinoma in situ of the nasal cavity",
          "nasal cavity carcinoma in situ",
          "nasal cavity in situ carcinoma",
          "stage 0 carcinoma of nasal cavity",
          "stage 0 carcinoma of the nasal cavity",
          "stage 0 nasal cavity cancer",
          "stage 0 nasal cavity cancer aJCC v6, v7, and v8",
          "stage 0 nasal cavity carcinoma",
          "stage 0 nasal cavity carcinoma aJCC v6",
          "stage 0 nasal cavity carcinoma aJCC v7",
          "stage 0 nasal cavity carcinoma aJCC v8"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A in situ carcinoma that involves the nasal cavity."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003784"
    },
    {
      "id": 6427,
      "label": "skin carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4707,
        6433
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8687",
          "ICD10CM:D04",
          "ICD9:232",
          "ICD9:232.0",
          "ICD9:232.2",
          "ICD9:232.3",
          "ICD9:232.4",
          "ICD9:232.5",
          "ICD9:232.6",
          "ICD9:232.7",
          "ICD9:232.8",
          "ICD9:232.9",
          "MEDGEN:102308",
          "NCIT:C3640",
          "SCTID:92749008",
          "UMLS:C0154073"
        ],
        "synonyms": [
          "carcinoma in situ of skin",
          "carcinoma in situ of the skin",
          "carcinoma in situ of zone of skin",
          "carcinoma of skin stage 0",
          "carcinoma of the skin stage 0",
          "cutaneous carcinoma in situ",
          "nonmelanoma carcinoma in situ",
          "skin cancer stage 0",
          "skin carcinoma in situ",
          "skin carcinoma stage 0",
          "stage 0 nonmelanoma skin carcinoma in situ",
          "stage 0 skin cancer",
          "stage 0 skin cancer aJCC v6",
          "stage 0 skin cancer aJCC v7",
          "stage 0 skin carcinoma",
          "stage 0 zone of skin carcinoma",
          "zone of skin carcinoma in situ",
          "zone of skin in situ carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the zone of skin."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004641"
    },
    {
      "id": 6442,
      "label": "breast carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6730
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8791",
          "ICD10CM:D05",
          "ICD9:233.0",
          "MEDGEN:57817",
          "MESH:D000071960",
          "NCIT:C3641",
          "SCTID:189336000",
          "UMLS:C0154084",
          "icd11.foundation:1264360394"
        ],
        "synonyms": [
          "breast cancer in situ",
          "breast cancer stage 0",
          "breast carcinoma in situ",
          "breast in situ carcinoma",
          "carcinoma in situ of breast",
          "carcinoma in situ of the breast",
          "in situ breast cancer",
          "non-infiltrating breast carcinoma",
          "non-infiltrating carcinoma of breast",
          "non-infiltrating carcinoma of the breast",
          "non-invasive breast carcinoma",
          "non-invasive carcinoma of breast",
          "non-invasive carcinoma of the breast",
          "stage 0 breast cancer",
          "stage 0 breast cancer aJCC v6",
          "stage 0 breast cancer aJCC v6 and v7",
          "stage 0 breast cancer aJCC v7",
          "stage 0 breast carcinoma",
          "stage 0 breast carcinoma in situ",
          "stage 0 carcinoma of breast",
          "stage 0 carcinoma of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the breast."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004658"
    },
    {
      "id": 6443,
      "label": "eye carcinoma in situ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4546,
        6433
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8792",
          "ICD10CM:D09.2",
          "ICD9:234.0",
          "MEDGEN:509519",
          "SCTID:92590009",
          "UMLS:C0154094"
        ],
        "synonyms": [
          "carcinoma in situ of eye",
          "carcinoma in situ of eyeball of camera-type eye",
          "eye in situ carcinoma",
          "eyeball of camera-type eye carcinoma in situ",
          "stage 0 eye carcinoma",
          "stage 0 eyeball of camera-type eye carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A carcinoma in situ involving a eye."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004659"
    },
    {
      "id": 6444,
      "label": "lung carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6862
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8800",
          "ICD9:231.2",
          "MEDGEN:146894",
          "NCIT:C27467",
          "SCTID:92649001",
          "UMLS:C0685053"
        ],
        "synonyms": [
          "bronchial carcinoma in situ",
          "carcinoma in situ of lung",
          "lung in situ carcinoma",
          "stage 0 lung cancer",
          "stage 0 lung cancer aJCC v6",
          "stage 0 lung cancer aJCC v6 and v7",
          "stage 0 lung cancer aJCC v7",
          "stage 0 lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A carcinoma in situ involving a lung."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004660"
    },
    {
      "id": 6473,
      "label": "squamous carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8070/2",
          "ICDO:8077/2",
          "MEDGEN:83116",
          "NCIT:C27093",
          "UMLS:C0334245"
        ],
        "synonyms": [
          "carcinoma, squamous cell, in situ, malignant",
          "epidermoid carcinoma in situ",
          "epidermoid cell carcinoma in situ",
          "grade 3 SIN",
          "grade 3 squamous intraepithelial neoplasia",
          "grade III SIN",
          "grade III squamous intraepithelial neoplasia",
          "intraepithelial squamous cell carcinoma",
          "squamous carcinoma in situ",
          "squamous cell carcinoma in situ",
          "squamous cell carcinoma in-situ",
          "stage 0 squamous cell carcinoma",
          "CIN III",
          "CIN III - carcinoma in situ of cervix",
          "CIN III - severe dyskaryosis",
          "carcinoma in situ of cervix",
          "carcinoma in situ of uterine cervix",
          "cervical intraepithelial neoplasia grade III with severe dysplasia",
          "cervix Ca in situ",
          "severe dysplasia of cervix",
          "severe dysplasia of the cervix uteri",
          "squamous intraepithelial neoplasia, grade III",
          "stage 0 uterine cervix carcinoma",
          "uterine cervix in situ carcinoma"
        ],
        "definition": "A malignant epithelial neoplasm confined to the squamous epithelium, without invasion of the underlying tissues."
      },
      "child_count": 6,
      "reference_id": "MONDO:0004693"
    },
    {
      "id": 6476,
      "label": "larynx carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4457,
        6433
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9011",
          "GARD:0027702",
          "ICD10CM:D02.0",
          "ICD9:231.0",
          "MEDGEN:56336",
          "NCIT:C9100",
          "SCTID:92634009",
          "UMLS:C0154069"
        ],
        "synonyms": [
          "carcinoma in situ of larynx",
          "carcinoma in situ of the larynx",
          "laryngeal cancer stage 0",
          "laryngeal carcinoma in situ",
          "laryngeal carcinoma stage 0",
          "larynx carcinoma in situ",
          "larynx in situ carcinoma",
          "stage 0 carcinoma of larynx",
          "stage 0 carcinoma of the larynx",
          "stage 0 laryngeal cancer",
          "stage 0 laryngeal cancer aJCC v6",
          "stage 0 laryngeal cancer aJCC v6, v7, and V8",
          "stage 0 laryngeal cancer aJCC v7",
          "stage 0 laryngeal cancer aJCC v8",
          "stage 0 laryngeal carcinoma",
          "stage 0 laryngeal carcinoma in situ",
          "stage 0 laryngeal throat cancer",
          "stage 0 larynx carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the larynx."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004696"
    },
    {
      "id": 6478,
      "label": "intestine carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        7430,
        7738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9024",
          "ICD9:230.7",
          "MEDGEN:672856",
          "SCTID:92617001",
          "UMLS:C0685941"
        ],
        "synonyms": [
          "carcinoma in situ of intestine",
          "intestine in situ carcinoma",
          "stage 0 intestine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma in situ involving a intestine."
      },
      "child_count": 6,
      "reference_id": "MONDO:0004698"
    },
    {
      "id": 6483,
      "label": "bladder carcinoma in situ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5789,
        6433,
        7681
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9053",
          "GARD:0024091",
          "ICD10CM:D09.0",
          "ICD9:233.7",
          "MEDGEN:57584",
          "NCIT:C3644",
          "SCTID:92546004",
          "UMLS:C0154091"
        ],
        "synonyms": [
          "cancer in situ of urinary bladder",
          "bladder flat CIS",
          "bladder flat carcinoma in situ",
          "carcinoma in situ of bladder",
          "carcinoma in situ of the urinary bladder",
          "carcinoma in situ of urinary bladder",
          "flat CIS of the bladder",
          "flat CIS of the urinary bladder",
          "flat carcinoma in situ of the bladder",
          "flat carcinoma in situ of the urinary bladder",
          "high grade bladder Intraurothelial neoplasia",
          "stage 0 urinary bladder carcinoma",
          "stage 0is bladder cancer",
          "stage 0is bladder carcinoma",
          "stage 0is bladder urothelial cancer",
          "stage 0is bladder urothelial carcinoma",
          "stage 0is bladder urothelial carcinoma aJCC v6",
          "stage 0is bladder urothelial carcinoma aJCC v6 and v7",
          "stage 0is bladder urothelial carcinoma aJCC v7",
          "stage 0is carcinoma of bladder",
          "stage 0is carcinoma of the bladder",
          "stage 0is carcinoma of the urinary bladder",
          "stage 0is carcinoma of urinary bladder",
          "stage 0is urinary bladder carcinoma",
          "urinary bladder carcinoma in situ",
          "urinary bladder flat CIS",
          "urinary bladder flat carcinoma in situ",
          "urinary bladder in situ carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Also known as carcinoma in situ of the urinary bladder or high grade intraurothelial neoplasia, this is a flat lesion of the transitional cell epithelium characterized by severe cytologic atypia. This lesion is confined to the urothelium, and is a precursor of invasive transitional cell carcinoma of the bladder. Stage 0is includes: Tis, N0, M0. Tis: Carcinoma in situ: \"flat tumor\". N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0004703"
    },
    {
      "id": 6487,
      "label": "esophagus carcinoma in situ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6433,
        18977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9095",
          "GARD:0024094",
          "ICD10CM:D00.1",
          "ICD9:230.1",
          "MEDGEN:56332",
          "NCIT:C89771",
          "SCTID:92585006",
          "UMLS:C0154059",
          "icd11.foundation:218644880"
        ],
        "synonyms": [
          "carcinoma in situ of esophagus",
          "carcinoma in situ of oesophagus",
          "esophageal carcinoma in situ",
          "esophageal carcinoma in situ aJCC v7",
          "esophagus in situ carcinoma",
          "oesophagus in situ carcinoma",
          "severe esophageal dysplasia",
          "severe esophageal dysplasia aJCC v7",
          "stage 0 esophageal cancer",
          "stage 0 esophageal cancer aJCC v7",
          "stage 0 esophageal carcinoma in situ",
          "stage 0 esophagus carcinoma",
          "stage 0 oesophagus carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Stage 0 includes: For squamous cell carcinoma: Tis (HGD), N0, M0, G1, GX, Tumor location: Any. For adenocarcinoma: Tis (HGD), N0, M0, G1, GX. Tis: High-grade dysplasia. N0: No regional lymph node metastasis. M0: No distant metastasis. G1: Well differentiated. GX: Grade cannot be assessed-stage grouping as G1. Tumor location: Location of the primary cancer site is defined by the position of the upper (proximal) edge of the tumor in the esophagus. (AJCC 7th ed.)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0004708"
    },
    {
      "id": 6489,
      "label": "uterus carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6929
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9108",
          "ICD9:233.2",
          "MEDGEN:673127",
          "SCTID:92788005",
          "UMLS:C0686237"
        ],
        "synonyms": [
          "carcinoma in situ of uterus",
          "stage 0 uterus carcinoma",
          "uterus in situ carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A carcinoma in situ involving a uterus."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004710"
    },
    {
      "id": 6493,
      "label": "liver carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        18551
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9132",
          "GARD:0024097",
          "ICD10CM:D01.5",
          "ICD9:230.8",
          "MEDGEN:577201",
          "SCTID:92644006",
          "UMLS:C0345908",
          "icd11.foundation:1380265780"
        ],
        "synonyms": [
          "carcinoma in situ of liver",
          "carcinoma in situ of liver, gallbladder and bile ducts",
          "liver in situ carcinoma",
          "stage 0 liver carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma in situ involving a liver."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004715"
    },
    {
      "id": 6494,
      "label": "stomach carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6695
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9138",
          "GARD:0027704",
          "ICD10CM:D00.2",
          "ICD9:230.2",
          "MEDGEN:56333",
          "NCIT:C7788",
          "SCTID:92756002",
          "UMLS:C0154060",
          "icd11.foundation:2040861039"
        ],
        "synonyms": [
          "carcinoma in situ of stomach",
          "carcinoma in situ of the stomach",
          "carcinoma of stomach stage 0",
          "carcinoma of the stomach stage 0",
          "gastric carcinoma in situ",
          "gastric carcinoma stage 0",
          "gastric carcinoma, stage 0",
          "stage 0 carcinoma of stomach",
          "stage 0 carcinoma of the stomach",
          "stage 0 gastric (stomach) cancer",
          "stage 0 gastric cancer",
          "stage 0 gastric cancer aJCC v6",
          "stage 0 gastric cancer aJCC v6 and v7",
          "stage 0 gastric cancer aJCC v7",
          "stage 0 gastric carcinoma",
          "stage 0 gastric carcinoma in situ",
          "stage 0 stomach cancer",
          "stage 0 stomach carcinoma",
          "stomach carcinoma in situ",
          "stomach carcinoma stage 0",
          "stomach in situ carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the stomach."
      },
      "child_count": 6,
      "reference_id": "MONDO:0004716"
    },
    {
      "id": 6508,
      "label": "kidney carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6923
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9234",
          "ICD9:233.9",
          "MEDGEN:673070",
          "SCTID:92624000",
          "UMLS:C0686172"
        ],
        "synonyms": [
          "carcinoma in situ of kidney",
          "kidney in situ carcinoma",
          "stage 0 kidney carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A carcinoma in situ involving a kidney."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004732"
    },
    {
      "id": 7787,
      "label": "grade III prostatic intraepithelial neoplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6433,
        6882,
        6913
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8634",
          "EFO:1000283",
          "ICD10CM:D07.5",
          "ICD9:233.4",
          "MEDGEN:1684800",
          "NCIT:C3642",
          "SCTID:92691004",
          "UMLS:C5200982"
        ],
        "synonyms": [
          "PIN III",
          "adenocarcinoma in situ of prostate",
          "adenocarcinoma in situ of the prostate",
          "carcinoma in situ of prostate",
          "carcinoma in situ of prostate gland",
          "grade 3 pin",
          "grade 3 prostatic intraepithelial neoplasia",
          "grade III pin",
          "pin III",
          "prostate adenocarcinoma in situ",
          "prostate carcinoma in situ",
          "prostate gland carcinoma in situ",
          "prostate gland in situ carcinoma",
          "stage 0 prostate gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "High grade prostatic intraepithelial neoplasia characterized by the presence of severe architectural and cytologic abnormalities."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006234"
    },
    {
      "id": 20475,
      "label": "carcinoma in situ of ureter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6433,
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:233.9",
          "MEDGEN:1660901",
          "NCIT:C4529",
          "SCTID:92782006",
          "UMLS:C4721448"
        ],
        "synonyms": [
          "carcinoma in situ of the ureter",
          "carcinoma in situ of ureter",
          "stage 0 ureter carcinoma",
          "stage 0is carcinoma of the ureter",
          "stage 0is carcinoma of ureter",
          "stage 0is ureter cancer",
          "stage 0is ureter cancer aJCC v7",
          "stage 0is ureter carcinoma",
          "stage 0is ureter urothelial cancer",
          "stage 0is ureter urothelial carcinoma",
          "stage 0is ureter urothelial carcinoma aJCC v7",
          "stage 0is ureteral carcinoma",
          "ureter cancer stage 0is",
          "ureter carcinoma in situ",
          "ureter in situ carcinoma",
          "ureteral carcinoma in situ"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the ureter."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021284"
    },
    {
      "id": 20476,
      "label": "carcinoma in situ of urethra",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6433,
        20506
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027879",
          "ICD9:233.9",
          "MEDGEN:1661236",
          "NCIT:C4531",
          "SCTID:92784007",
          "UMLS:C4721449"
        ],
        "synonyms": [
          "carcinoma in situ of the urethra",
          "carcinoma in situ of urethra",
          "stage 0 urethra carcinoma",
          "stage 0is carcinoma of the urethra",
          "stage 0is carcinoma of urethra",
          "stage 0is urethra carcinoma",
          "stage 0is urethral cancer",
          "stage 0is urethral cancer aJCC v7",
          "stage 0is urethral carcinoma",
          "urethra carcinoma in situ",
          "urethra in situ carcinoma",
          "urethral carcinoma in situ"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the urethra."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021285"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    },
    {
      "id": 20078,
      "label": "high grade malignant neoplasm"
    },
    {
      "id": 20315,
      "label": "precancerous condition"
    }
  ]
}