{
  "id": 6439,
  "label": "atypical chronic myeloid leukemia, BCR-ABL1 negative",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004653",
  "properties": {
    "xrefs": [
      "DOID:0060597",
      "DOID:8747",
      "GARD:0019583",
      "ICDO:9876/3",
      "MEDGEN:266233",
      "MedDRA:10054651",
      "NCIT:C3519",
      "Orphanet:98824",
      "SCTID:277589003",
      "UMLS:C1292772",
      "icd11.foundation:331838766"
    ],
    "synonyms": [
      "aCML",
      "atypical CML",
      "atypical chronic myeloid leukaemia",
      "atypical chronic myeloid leukemia",
      "atypical chronic myeloid leukemia, BCR-ABL1 Negative",
      "subacute granulocytic leukaemia",
      "subacute granulocytic leukemia",
      "subacute myelogenous leukaemia",
      "subacute myelogenous leukemia",
      "subacute myeloid leukaemia",
      "subacute myeloid leukemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A myelodysplastic/myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a Philadelphia chromosome or the BCR/ABL fusion gene. (WHO, 2001)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6429,
      "label": "myeloid leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6789,
        19727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8692",
          "GARD:0008226",
          "ICD10CM:C92",
          "ICD9:205",
          "ICD9:205.80",
          "ICD9:205.9",
          "ICD9:205.90",
          "ICDO:9860/3",
          "MEDGEN:7320",
          "MESH:D007951",
          "NCIT:C3172",
          "SCTID:188732008",
          "UMLS:C0023470"
        ],
        "synonyms": [
          "leukaemia granulocytic",
          "leukaemia myeloid",
          "leukemia granulocytic",
          "leukemia myelogenous",
          "leukemia myeloid",
          "leukemia, granulocytic, malignant",
          "myelocytic leukaemia",
          "myelocytic leukemia",
          "myelogenous leukaemia",
          "myelogenous leukemia",
          "myeloid leukemia",
          "non-lymphoblastic leukaemia",
          "non-lymphoblastic leukemia",
          "non-lymphocytic leukaemia",
          "non-lymphocytic leukemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are immature myeloid cells and myeloblasts, it is called acute myeloid leukemia. When the proliferating myeloid cells are neutrophils, it is called chronic myelogenous leukemia."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004643"
    },
    {
      "id": 7847,
      "label": "myelodysplastic/myeloproliferative neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4972",
          "EFO:1000388",
          "GARD:0024368",
          "ICDO:9975/3",
          "MEDGEN:226981",
          "NCIT:C27262",
          "ONCOTREE:MDS%2FMPN",
          "SCTID:445738007",
          "UMLS:C1301355"
        ],
        "synonyms": [
          "MDS-MPD",
          "MDS/MPD",
          "myelodysplastic myeloproliferative disease",
          "myelodysplastic/myeloproliferative disease",
          "myelodysplastic/myeloproliferative diseases",
          "myelodysplastic/myeloproliferative disorder",
          "myelodysplastic/myeloproliferative disorders",
          "myeloproliferative/myelodysplastic disorders",
          "myeloproliferative/myelodysplastic syndromes",
          "MDS/MPN",
          "MPD-MDS",
          "MPD/MDS",
          "myelodysplastic/myeloproliferative neoplasm",
          "myelodysplastic/myeloproliferative neoplasms"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A category of clonal hematopoietic disorders that have both myelodysplastic and myeloproliferative features at the time of initial presentation."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006311"
    },
    {
      "id": 19728,
      "label": "myelodysplastic/myeloproliferative disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16513
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009351",
          "MESH:D054437",
          "Orphanet:98275"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Clonal myeloid disorders that possess both dysplastic and proliferative features but are not properly classified as either MYELODYSPLASTIC SYNDROMES or MYELOPROLIFERATIVE disorderS."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020077"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6429,
      "label": "myeloid leukemia"
    },
    {
      "id": 7847,
      "label": "myelodysplastic/myeloproliferative neoplasm"
    },
    {
      "id": 19728,
      "label": "myelodysplastic/myeloproliferative disease"
    }
  ]
}