{
  "id": 6500,
  "label": "submandibular gland cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004724",
  "properties": {
    "xrefs": [
      "DOID:9173",
      "GARD:0027705",
      "ICD10CM:C08.0",
      "ICD9:142.1",
      "MEDGEN:57782",
      "NCIT:C3526",
      "NCIT:C8396",
      "SCTID:363380002",
      "UMLS:C0153360"
    ],
    "synonyms": [
      "cancer of submandibular gland",
      "malignant neoplasm of submandibular gland",
      "malignant neoplasm of submaxillary gland",
      "malignant submandibular gland neoplasm",
      "malignant tumor of submandibular gland",
      "malignant tumor of the submandibular gland",
      "malignant tumour of submandibular gland",
      "malignant tumour of the submandibular gland",
      "submandibular gland cancer",
      "carcinoma of submandibular gland",
      "carcinoma of the submandibular gland",
      "submandibular gland carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "A malignant neoplasm involving the submandibular gland."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7827,
      "label": "major salivary gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2972,
        23418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000344",
          "GARD:0027745",
          "MEDGEN:235287",
          "NCIT:C5907",
          "UMLS:C1334549"
        ],
        "synonyms": [
          "major salivary gland cancer",
          "carcinoma of Major salivary gland",
          "carcinoma of major salivary gland",
          "carcinoma of the major salivary gland",
          "major salivary gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A carcinoma that arises from the parotid gland, submandibular gland, or sublingual gland."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006284"
    },
    {
      "id": 20453,
      "label": "submandibular gland neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3796,
        20529
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001853",
          "MEDGEN:20986",
          "MESH:D013365",
          "NCIT:C3393",
          "SCTID:254464000",
          "UMLS:C0038558"
        ],
        "synonyms": [
          "neoplasm of submandibular gland",
          "neoplasm of the submandibular gland",
          "submandibular gland neoplasm (disease)",
          "submandibular gland tumor",
          "submandibular gland tumour",
          "tumor of submandibular gland",
          "tumor of the submandibular gland",
          "tumour of submandibular gland",
          "tumour of the submandibular gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the submandibular gland."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021244"
    }
  ],
  "children": [
    {
      "id": 7948,
      "label": "submandibular gland adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6500,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000554",
          "GARD:0027756",
          "MEDGEN:234370",
          "NCIT:C5940",
          "UMLS:C1336521"
        ],
        "synonyms": [
          "adenocarcinoma of submandibular gland",
          "adenocarcinoma of the submandibular gland",
          "submandibular gland adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the submandibular gland. Representative examples include polymorphic low-grade adenocarcinoma and acinic cell carcinoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006435"
    },
    {
      "id": 7949,
      "label": "submandibular gland adenoid cystic carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6500,
        23547
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000555",
          "GARD:0024412",
          "MEDGEN:277773",
          "NCIT:C5935",
          "SCTID:423189008",
          "UMLS:C1336522"
        ],
        "synonyms": [
          "adenoid cystic carcinoma of submandibular gland",
          "adenoid cystic carcinoma of the submandibular gland",
          "submandibular gland adenoid cystic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "An aggressive carcinoma that arises from the submandibular gland. It is characterized by the presence of malignant epithelial and myoepithelial cells forming cribriform, tubular, and solid patterns. It usually presents as a slow growing mass. Patients develop pain because of the tendency of these carcinomas to invade perineural tissues."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006436"
    },
    {
      "id": 20470,
      "label": "mucoepidermoid carcinoma of submandibular gland",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6500,
        7829
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025302",
          "MEDGEN:277774",
          "NCIT:C5939",
          "SCTID:423424005",
          "UMLS:C1336524"
        ],
        "synonyms": [
          "mucoepidermoid carcinoma of the submandibular gland",
          "submandibular gland mucoepidermoid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A mucoepidermoid carcinoma that involves the submandibular gland."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021279"
    }
  ],
  "roots": [
    {
      "id": 7827,
      "label": "major salivary gland carcinoma"
    },
    {
      "id": 20453,
      "label": "submandibular gland neoplasm"
    }
  ]
}