{
  "id": 6535,
  "label": "intrinsic asthma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004765",
  "properties": {
    "xrefs": [
      "DOID:9360",
      "ICD9:493.1",
      "MEDGEN:510123",
      "SCTID:266361008",
      "UMLS:C0155880"
    ],
    "synonyms": [
      "non-allergic asthma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "An asthma that is triggered by factors not related to allergies such as anxiety, stress, exercise, cold air, dry air, hyperventilation, smoke, viruses, chemical irritants, autonomic imbalance, hormonal deficiencies and psychogenic influences. It is characterized by airway obstruction and inflammation that is at least partially reversible with medication. The symptoms include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6720,
      "label": "asthma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3582
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2841",
          "HP:0002099",
          "ICD10CM:J45",
          "ICD10WHO:J45",
          "ICD9:493",
          "ICD9:493.81",
          "ICD9:493.9",
          "MEDGEN:2109",
          "MESH:D001249",
          "NCIT:C28397",
          "SCTID:31387002",
          "UMLS:C0004096",
          "icd11.foundation:1656445230"
        ],
        "synonyms": [
          "chronic obstructive asthma",
          "chronic obstructive asthma with acute exacerbation",
          "chronic obstructive asthma with status asthmaticus",
          "exercise induced asthma",
          "exercise-induced asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004979"
    }
  ],
  "children": [
    {
      "id": 25190,
      "label": "environmental induced asthma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6535
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080819"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An intrinsic asthma that is characterized by exposure to tobacco smoke and other inflammatory gasses or particulate matter."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850285"
    },
    {
      "id": 25191,
      "label": "exercise-induced bronchoconstriction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6535
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080821",
          "MEDGEN:4606",
          "UMLS:C0015263"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An intrinsic asthma that is characterized by narrowing of the airways during or shortly after exercise."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850286"
    },
    {
      "id": 25192,
      "label": "aspirin-induced respiratory disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6535
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080822"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An intrinsic asthma that is characertized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850287"
    }
  ],
  "roots": [
    {
      "id": 6720,
      "label": "asthma"
    }
  ]
}