{
  "id": 6556,
  "label": "cholangitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004789",
  "properties": {
    "xrefs": [
      "DOID:9446",
      "ICD10CM:K83.0",
      "ICD9:576.1",
      "MEDGEN:40258",
      "MESH:D002761",
      "NCIT:C26718",
      "SCTID:82403002",
      "UMLS:C0008311",
      "icd11.foundation:1712178777"
    ],
    "synonyms": [
      "biliary tract infection",
      "biliary tree inflammation",
      "cholangitis",
      "inflammation of biliary tree"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An acute or chronic inflammatory process affecting the biliary tract."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 7855,
      "label": "non-neoplastic bile duct disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4900,
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000400",
          "MEDGEN:476793",
          "NCIT:C35774",
          "UMLS:C3275160"
        ],
        "synonyms": [
          "non-neoplastic bile duct disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-neoplastic disorder that affects the intrahepatic or extrahepatic bile ducts. Representative examples include cholangitis and biliary atresia."
      },
      "child_count": 10,
      "reference_id": "MONDO:0006322"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 4100,
      "label": "suppurative cholangitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6556
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14269",
          "MEDGEN:82766",
          "NCIT:C35336",
          "SCTID:69850007",
          "UMLS:C0267924",
          "icd11.foundation:32799822"
        ],
        "synonyms": [
          "suppurative cholangitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Cholangitis that is characterized by pyogenic organisms."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001928"
    },
    {
      "id": 4101,
      "label": "ascending cholangitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6556
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14270",
          "MEDGEN:81387",
          "NCIT:C35372",
          "SCTID:26918003",
          "UMLS:C0311273"
        ],
        "synonyms": [
          "ascending cholangitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Acute infection of the bile ducts caused by bacteria ascending from the small intestine."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001929"
    },
    {
      "id": 4102,
      "label": "acute cholangitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6556,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14271",
          "MEDGEN:82764",
          "NCIT:C35334",
          "SCTID:6215006",
          "UMLS:C0267917"
        ],
        "synonyms": [
          "acute cholangitis",
          "cholangitis, acute"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Cholangitis that is both sudden in onset and of a relatively short duration."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001930"
    },
    {
      "id": 4103,
      "label": "pericholangitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6556
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14272",
          "MEDGEN:18381",
          "NCIT:C34916",
          "SCTID:111373008",
          "UMLS:C0031052"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Inflammation of the tissue surrounding the biliary ducts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001931"
    },
    {
      "id": 4284,
      "label": "cholecystitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6556,
        6977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1949",
          "ICD10CM:K81",
          "ICD10WHO:K81",
          "ICD9:575.10",
          "ICD9:575.11",
          "MEDGEN:920",
          "MESH:D002764",
          "NCIT:C34465",
          "SCTID:20824003",
          "UMLS:C0008325",
          "icd11.foundation:786251500"
        ],
        "synonyms": [
          "acute and chronic cholecystitis",
          "gall bladder inflammation",
          "inflammation of gall bladder",
          "acute cholecystitis",
          "acute on chronic cholecystitis",
          "chronic cholecystitis",
          "acalculous cholecystitis",
          "gallstone cholecystitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An acute or chronic inflammation involving the gallbladder wall. It may be associated with the presence of gallstones."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002155"
    },
    {
      "id": 6553,
      "label": "chronic cholangitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6556
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9439",
          "MEDGEN:82765",
          "NCIT:C35335",
          "SCTID:71912000",
          "UMLS:C0267918"
        ],
        "synonyms": [
          "cholangitis, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Cholangitis that is persistent and long-standing."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004786"
    },
    {
      "id": 18642,
      "label": "sclerosing cholangitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6556
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14268",
          "EFO:0004268",
          "GARD:0021868",
          "HP:0030991",
          "MEDGEN:3036",
          "NANDO:1200440",
          "NANDO:2100265",
          "NCIT:C4828",
          "Orphanet:447771",
          "SCTID:235917005",
          "UMLS:C0008313"
        ],
        "synonyms": [
          "Primary sclerosing cholangitis",
          "primary sclerosing cholangitis (PSC)",
          "sclerosing cholangitis",
          "sclerosing cholangitis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure."
      },
      "child_count": 5,
      "reference_id": "MONDO:0018646"
    },
    {
      "id": 22780,
      "label": "primary biliary cholangitis/primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6556,
        16828
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022250",
          "MEDGEN:1812237",
          "Orphanet:562639",
          "UMLS:C5680117"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0034189"
    },
    {
      "id": 25178,
      "label": "autoimmune cholangitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6556,
        16828
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080742",
          "GARD:0026594",
          "MEDGEN:881331",
          "UMLS:C4075851"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An autoimmune hepatitis that is characterized by primary biliary cirrhosis clinical, biochemical, and histologic characteristics with antinuclear antibody positive sera."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850225"
    }
  ],
  "roots": [
    {
      "id": 7855,
      "label": "non-neoplastic bile duct disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}