{
  "id": 6588,
  "label": "fasciitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004830",
  "properties": {
    "xrefs": [
      "DOID:9598",
      "HP:0100537",
      "ICD9:729.4",
      "MEDGEN:4658",
      "MESH:D005208",
      "NCIT:C50559",
      "SCTID:36948007",
      "UMLS:C0015645"
    ],
    "synonyms": [
      "Fascitis",
      "fascia inflammation",
      "fasciitis",
      "fasciitis (disease)",
      "inflammation of fascia"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "Inflammation process in fascia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 4222,
      "label": "musculoskeletal system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:17",
          "EFO:0009676",
          "ICD9:729.99",
          "MEDGEN:6471",
          "MESH:D009140",
          "NCIT:C107377",
          "SCTID:928000",
          "UMLS:C0026857"
        ],
        "synonyms": [
          "disease of musculoskeletal system",
          "disease or disorder of musculoskeletal system",
          "disorder of musculoskeletal system",
          "musculoskeletal disease",
          "musculoskeletal system disease",
          "musculoskeletal system disease or disorder",
          "musculoskeletal system disorder",
          "musculoskeletal disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disease involving the musculoskeletal system."
      },
      "child_count": 22,
      "reference_id": "MONDO:0002081"
    },
    {
      "id": 5762,
      "label": "connective tissue disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:65",
          "EFO:1001986",
          "MEDGEN:1098",
          "MESH:D003240",
          "NANDO:2100172",
          "NCIT:C26729",
          "SCTID:105969002",
          "UMLS:C0009782"
        ],
        "synonyms": [
          "connective tissue disease",
          "connective tissue disease or disorder",
          "connective tissue diseases",
          "connective tissue disorder",
          "connective tissue disorders",
          "disease of connective tissue",
          "disease or disorder of connective tissue",
          "disease, connective tissue",
          "disorder of connective tissue",
          "primary disorder of connective tissue",
          "tissue disease, connective"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A disease involving the connective tissue."
      },
      "child_count": 16,
      "reference_id": "MONDO:0003900"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 6009,
      "label": "nodular fasciitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6588,
        7762,
        7941,
        19144
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7327",
          "GARD:0021959",
          "ICD10CM:M72.4",
          "ICD9:728.79",
          "MEDGEN:96076",
          "NCIT:C3827",
          "Orphanet:477742",
          "SCTID:400138001",
          "UMLS:C0410005",
          "icd11.foundation:789101380"
        ],
        "synonyms": [
          "nodular fasciitis",
          "pseudosarcomatous fasciitis",
          "pseudosarcomatous fibromatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A self-limiting, rapidly growing, non-encapsulated benign neoplasm that arises from the soft tissues. It is characterized by the presence of plump spindle-shaped fibroblasts, multinucleated osteoclast-like giant cells, chronic inflammatory infiltrate, red blood cell extravasation, and high mitotic activity."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004187"
    },
    {
      "id": 6589,
      "label": "proliferative fasciitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6588
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9599",
          "MEDGEN:98496",
          "NCIT:C4728",
          "SCTID:254737002",
          "UMLS:C0432528"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rapidly growing, poorly circumscribed, mass-forming proliferation that arises from the subcutaneous tissues. It is characterized by the presence of spindle-shaped fibroblasts, round ganglion-like cells, myxoid to collagenous stroma formation, and high mitotic activity. It recurs only rarely following local excision and does not metastasize."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004831"
    },
    {
      "id": 6591,
      "label": "plantar fasciitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6588
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9600",
          "MEDGEN:56201",
          "MESH:D036981",
          "SCTID:202882003",
          "UMLS:C0149756",
          "icd11.foundation:254630809"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Inflammation of the thick tissue on the bottom of the foot (plantar fascia) causing heel pain. The plantar fascia (also called plantar aponeurosis) are bands of fibrous tissue extending from the calcaneal tuberosity to the toes. The etiology of plantar fasciitis remains controversial but is likely to involve a biomechanical imbalance. Though often presenting along with heel spur, they do not appear to be causally related."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004833"
    },
    {
      "id": 6592,
      "label": "ischemic fasciitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6588
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9601",
          "MEDGEN:220988",
          "NCIT:C6483",
          "SCTID:403990005",
          "UMLS:C1304514"
        ],
        "synonyms": [
          "atypical decubital fibroplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A reactive, painless lesion which is characterized by a pseudosarcomatous proliferation of fibroblasts and myofibroblasts usually in the deep subcutaneous tissue. It occurs mainly around the limb girdles, sacral region, and greater trochanter. It affects mainly elderly patients and sometimes is associated with physical immobility. Local excision is usually curative."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004834"
    },
    {
      "id": 6593,
      "label": "necrotizing fasciitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6588
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9602",
          "ICD10CM:M72.6",
          "ICD9:728.86",
          "MEDGEN:66763",
          "MESH:D019115",
          "NCIT:C84916",
          "Orphanet:699697",
          "SCTID:52486002",
          "UMLS:C0238124"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Necrotizing fasciitis is a serious infection of the skin, the tissue just beneath the skin (subcutaneous tissue), and the tissue that covers internal organs (fascia). Necrotizing fasciitis can be caused by several different types of bacteria, and the infection can arise suddenly and spread quickly. Early signs include flu-like symptoms and redness and pain around the infection site. A prompt diagnosis and treatment are essential.If the infection is not treated promptly, it can lead to multiple organ failure and death. Treatment typically includes intravenous (IV) antibiotics and surgery to remove infected and dead tissue."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004835"
    },
    {
      "id": 10418,
      "label": "eosinophilic fasciitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6588,
        19745
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006351",
          "HP:0045029",
          "ICD9:728.89",
          "MEDGEN:82673",
          "MESH:C562487",
          "MedDRA:10014954",
          "NCIT:C112116",
          "OMIM:226350",
          "Orphanet:3165",
          "SCTID:24129002",
          "UMLS:C0264005",
          "icd11.foundation:1977389237"
        ],
        "synonyms": [
          "Shulman syndrome",
          "diffuse fasciitis with eosinophilia",
          "eosinophilic fasciitis",
          "eosinophilic fasciitis (disease)",
          "EF"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Eosinophilic fasciitis is a rare connective tissue disease that is characterized by inflammation and thickening of the fascia, usually associated with peripheral eosinophilia. It presents during adulthood with symmetrical and painful swelling of mainly the extremities that progressively become indurated. Fatigue, disabling cutaneous fibrosis, myositis and arthritis may also be observed."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009175"
    }
  ],
  "roots": [
    {
      "id": 4222,
      "label": "musculoskeletal system disorder"
    },
    {
      "id": 5762,
      "label": "connective tissue disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}