{
  "id": 6690,
  "label": "neurosyphilis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004944",
  "properties": {
    "xrefs": [
      "DOID:9988",
      "GARD:0008729",
      "ICD10CM:A52.3",
      "ICD9:094",
      "ICD9:094.89",
      "ICD9:094.9",
      "MEDGEN:14360",
      "MESH:D009494",
      "NCIT:C84935",
      "SCTID:26039008",
      "UMLS:C0027927",
      "icd11.foundation:2118246468"
    ],
    "synonyms": [
      "neurosyphilis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "Infection of the brain or spinal cord by Treponema pallidum. It occurs many years following the original infection which remained untreated. Signs and symptoms include abnormal gait, blindness, depression, paralysis, seizures and dementia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6299,
      "label": "tertiary syphilis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7568
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8200",
          "GARD:0027683",
          "ICD10CM:A52",
          "ICD9:095.8",
          "ICD9:095.9",
          "ICD9:097.0",
          "MEDGEN:56297",
          "MESH:C536774",
          "NCIT:C128414",
          "SCTID:72083004",
          "UMLS:C0153188"
        ],
        "synonyms": [
          "late syphilis",
          "late tertiary syphilis",
          "tertiary syphilis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A stage of syphilis that occurs fifteen to thirty years after the initial infection; it can include gumma formation and cardiovascular or central nervous system involvement (neurosyphilis)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004497"
    }
  ],
  "children": [
    {
      "id": 2849,
      "label": "parenchymatous neurosyphilis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6690
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050490",
          "GARD:0022749"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A tertiary neurosyphilis that results when chronic meningoencephalitis causes destruction of cortical parenchyma. The infection has symptom irritability, has symptom difficulty concentrating, has symptom deterioration of memory, has symptom defective judgment, has symptom headaches, has symptom insomnia, has symptom fatigue, and has symptom lethargy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000335"
    },
    {
      "id": 2850,
      "label": "meningovascular neurosyphilis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6690
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050491",
          "GARD:0022750"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A tertiary neurosyphilis that results in inflammation located in arteries of the brain or located in arteries of spinal cord. The infection has symptom headache, has symptom neck stiffness, has symptom dizziness, has symptom behavioral abnormalities, has symptom poor concentration, has symptom memory loss, has symptom lassitude, has symptom insomnia, has symptom blurred vision, has symptom weakness and wasting of shoulder-girdle and arm muscles, has symptom slowly progressive leg weakness with urinary or fecal incontinence or both, and has symptom paralysis of the legs due to thrombosis of spinal arteries."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000336"
    },
    {
      "id": 3197,
      "label": "asymptomatic neurosyphilis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6690
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10035",
          "GARD:0022847",
          "ICD10CM:A52.2",
          "ICD9:094.3",
          "MEDGEN:102259",
          "SCTID:37754005",
          "UMLS:C0153167",
          "icd11.foundation:453651926"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0000927"
    },
    {
      "id": 7569,
      "label": "tabes dorsalis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6690,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10027",
          "GARD:0008730",
          "ICD10CM:A52.11",
          "ICD9:094.0",
          "MEDGEN:21065",
          "MESH:D013606",
          "NCIT:C35057",
          "SCTID:316841006",
          "UMLS:C0039223",
          "icd11.foundation:1131342025"
        ],
        "synonyms": [
          "syphilitic myelopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of neurosyphilis characterized by slowly progressive degeneration of the spinal cord. Signs and symptoms include pain, ataxia, loss of coordination, personality changes, blindness, urinary incontinence, dementia, and degeneration of the joints."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005977"
    }
  ],
  "roots": [
    {
      "id": 6299,
      "label": "tertiary syphilis"
    }
  ]
}