{ "id": 6695, "label": "gastric carcinoma", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0004950", "properties": { "xrefs": [ "DOID:10538", "DOID:5517", "EFO:0000178", "GARD:0027710", "ICD9:151.3", "MEDGEN:147066", "NCIT:C4911", "SCTID:187741001", "UMLS:C0699791", "icd11.foundation:1503707183" ], "synonyms": [ "cancer of stomach", "cancer of the stomach", "gastric (stomach) cancer", "gastric cancer", "gastric cancer, NOS", "stomach cancer", "carcinoma of stomach", "carcinoma of the stomach", "gastric carcinoma", "stomach carcinoma", "Ca fundus - stomach", "cancer of fundus of stomach", "fundus of stomach cancer", "gastric fundus cancer", "malignant fundus of stomach neoplasm", "malignant neoplasm of fundus of stomach", "malignant tumor of fundus of stomach", "malignant tumour of fundus of stomach" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A carcinoma that arises from epithelial cells of the stomach." }, "isLeaf": false, "isRoot": false, "child_count": 12, "parents": [ { "id": 3312, "label": "gastric cancer", "isLeaf": false, "isRoot": false, "parents": [ 4587, 20326 ], "type_id": 0, "properties": { "xrefs": [ "DOID:10534", "GARD:0007704", "ICD10CM:C16", "ICD9:151", "ICD9:151.4", "ICD9:151.5", "ICD9:151.6", "ICD9:151.9", "MEDGEN:44264", "NCIT:C9331", "OMIM:613659", "UMLS:C0024623", "icd11.foundation:1397617262" ], "synonyms": [ "gastric neoplasm", "Ca lesser curvature - stomach", "GC", "cancer of stomach", "gastric cancer", "gastric cancer risk after h. pylori infection", "gastric cancer, somatic", "malignant gastric neoplasm", "malignant gastric tumor", "malignant gastric tumour", "malignant neoplasm of lesser curve of stomach", "malignant neoplasm of stomach", "malignant neoplasm of the stomach", "malignant stomach neoplasm", "malignant tumor of body of stomach", "malignant tumor of greater curve of stomach", "malignant tumor of lesser curve of stomach", "malignant tumor of stomach", "malignant tumor of the stomach", "malignant tumour of body of stomach", "malignant tumour of greater curve of stomach", "malignant tumour of lesser curve of stomach", "malignant tumour of stomach", "malignant tumour of the stomach", "stomach cancer", "Ca body - stomach", "ca greater curvature of stomach", "malignant neoplasm of body of stomach", "gastric cancer, intestinal" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A primary or metastatic malignant neoplasm involving the stomach." }, "child_count": 18, "reference_id": "MONDO:0001056" }, { "id": 7738, "label": "digestive system carcinoma", "isLeaf": false, "isRoot": false, "parents": [ 4587, 6734 ], "type_id": 0, "properties": { "xrefs": [ "DOID:0050922", "EFO:1000218", "HP:0002672", "MEDGEN:57467", "NCIT:C96963", "UMLS:C0151544" ], "synonyms": [ "carcinoma of digestive system", "carcinoma of the gastrointestinal system", "digestive system carcinoma", "gastrointestinal carcinoma", "gastrointestinal carcinoma (disease)", "gastrointestinal system carcinoma" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A malignant neoplasm that arises from the epithelium of any part of the digestive system. Representative examples include colorectal carcinoma, esophageal carcinoma, and pancreatic carcinoma." }, "child_count": 32, "reference_id": "MONDO:0006181" } ], "children": [ { "id": 5702, "label": "gastric cardia carcinoma", "isLeaf": false, "isRoot": false, "parents": [ 3318, 6695 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6270", "EFO:1001252", "GARD:0027649", "MEDGEN:234295", "NCIT:C6794", "UMLS:C1333763" ], "synonyms": [ "cancer of gastric cardia", "cancer of the gastric cardia", "carcinoma of cardia of stomach", "carcinoma of gastric cardia", "carcinoma of the cardia of the stomach", "carcinoma of the gastric cardia", "cardia of stomach carcinoma", "gastric cardia (stomach) cancer", "gastric cardia cancer" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A carcinoma that arises from epithelial cells of the cardia of stomach." }, "child_count": 4, "reference_id": "MONDO:0003834" }, { "id": 5827, "label": "gastric fundus carcinoma", "isLeaf": false, "isRoot": false, "parents": [ 6695 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6700", "GARD:0027658", "MEDGEN:87514", "NCIT:C8398", "SCTID:254555008", "UMLS:C0345799", "icd11.foundation:1208359113" ], "synonyms": [ "cancer of fundus of stomach", "cancer of gastric fundus", "cancer of the fundus of the stomach", "cancer of the gastric fundus", "gastric fundus (stomach) cancer", "carcinoma of fundus of stomach", "carcinoma of gastric fundus", "carcinoma of the fundus of the stomach", "carcinoma of the gastric fundus", "fundus of stomach carcinoma", "gastric fundus cancer" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A carcinoma that arises from epithelial cells of the fundus of stomach." }, "child_count": 1, "reference_id": "MONDO:0003970" }, { "id": 5828, "label": "gastric pylorus carcinoma", "isLeaf": true, "isRoot": false, "parents": [ 6695 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6703", "GARD:0027659", "MEDGEN:234301", "NCIT:C6795", "UMLS:C1333787" ], "synonyms": [ "cancer of gastric pylorus", "cancer of pylorus of stomach", "cancer of the gastric pylorus", "cancer of the pylorus of the stomach", "carcinoma of gastric pylorus", "carcinoma of pylorus of stomach", "carcinoma of the gastric pylorus", "carcinoma of the pylorus of the stomach", "gastric pylorus (stomach) cancer", "gastric pylorus cancer", "gastric pylorus carcinoma" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A carcinoma that arises from the pylorus." }, "child_count": 0, "reference_id": "MONDO:0003971" }, { "id": 5829, "label": "gastric body carcinoma", "isLeaf": false, "isRoot": false, "parents": [ 6695 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6705", "GARD:0027660", "MEDGEN:87515", "NCIT:C8399", "SCTID:254557000", "UMLS:C0345804" ], "synonyms": [ "body of stomach carcinoma", "cancer of body of stomach", "cancer of gastric body", "cancer of the body of the stomach", "cancer of the gastric body", "carcinoma of body of stomach", "carcinoma of gastric body", "carcinoma of the body of the stomach", "carcinoma of the gastric body", "gastric body (stomach) cancer", "gastric body cancer", "gastric body carcinoma" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A carcinoma that arises from epithelial cells of the body of stomach." }, "child_count": 1, "reference_id": "MONDO:0003972" }, { "id": 6494, "label": "stomach carcinoma in situ", "isLeaf": false, "isRoot": false, "parents": [ 6433, 6695 ], "type_id": 0, "properties": { "xrefs": [ "DOID:9138", "GARD:0027704", "ICD10CM:D00.2", "ICD9:230.2", "MEDGEN:56333", "NCIT:C7788", "SCTID:92756002", "UMLS:C0154060", "icd11.foundation:2040861039" ], "synonyms": [ "carcinoma in situ of stomach", "carcinoma in situ of the stomach", "carcinoma of stomach stage 0", "carcinoma of the stomach stage 0", "gastric carcinoma in situ", "gastric carcinoma stage 0", "gastric carcinoma, stage 0", "stage 0 carcinoma of stomach", "stage 0 carcinoma of the stomach", "stage 0 gastric (stomach) cancer", "stage 0 gastric cancer", "stage 0 gastric cancer aJCC v6", "stage 0 gastric cancer aJCC v6 and v7", "stage 0 gastric cancer aJCC v7", "stage 0 gastric carcinoma", "stage 0 gastric carcinoma in situ", "stage 0 stomach cancer", "stage 0 stomach carcinoma", "stomach carcinoma in situ", "stomach carcinoma stage 0", "stomach in situ carcinoma" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A in situ carcinoma that involves the stomach." }, "child_count": 6, "reference_id": "MONDO:0004716" }, { "id": 6770, "label": "gastric adenocarcinoma", "isLeaf": false, "isRoot": false, "parents": [ 6695, 6712 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3717", "EFO:0000503", "GARD:0027713", "MEDGEN:82961", "NCIT:C4004", "ONCOTREE:STAD", "Orphanet:464463", "SCTID:408647009", "UMLS:C0278701", "icd11.foundation:1855471719" ], "synonyms": [ "adenocarcinoma - stomach", "adenocarcinoma of stomach", "adenocarcinoma of the stomach", "gastric (stomach) adenocarcinoma", "gastric adenocarcinoma", "stomach adenocarcinoma", "STAD" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A carcinoma that arises from glandular epithelial cells of the stomach" }, "child_count": 18, "reference_id": "MONDO:0005036" }, { "id": 7782, "label": "gastric small cell neuroendocrine carcinoma", "isLeaf": true, "isRoot": false, "parents": [ 2894, 5092, 6695 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6552", "EFO:1000277", "GARD:0024342", "MEDGEN:272664", "NCIT:C6764", "ONCOTREE:STSC", "UMLS:C1333788" ], "synonyms": [ "Oat cell carcinoma of stomach", "Oat cell carcinoma of the stomach", "gastric Oat cell carcinoma", "gastric small cell carcinoma", "gastric small cell neuroendocrine carcinoma", "small cell carcinoma of stomach", "small cell carcinoma of the stomach", "stomach small cell carcinoma", "STSC" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005151", "name": "endocrine system disorder" } ], "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the stomach. It is characterized by the presence of malignant small cells." }, "child_count": 0, "reference_id": "MONDO:0006229" }, { "id": 7783, "label": "gastric squamous cell carcinoma", "isLeaf": false, "isRoot": false, "parents": [ 6695, 6823 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5516", "EFO:1000278", "GARD:0021743", "MEDGEN:234302", "NCIT:C5475", "Orphanet:418959", "SCTID:766980008", "UMLS:C1333789" ], "synonyms": [ "gastric (stomach) squamous cell cancer", "gastric squamous cell carcinoma", "squamous cell carcinoma of stomach", "squamous cell carcinoma of the stomach", "stomach squamous cell carcinoma" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A rare carcinoma of the stomach resembling squamous cell carcinomas arising elsewhere in the body." }, "child_count": 2, "reference_id": "MONDO:0006230" }, { "id": 18007, "label": "Epstein-Barr virus-associated gastric carcinoma", "isLeaf": true, "isRoot": false, "parents": [ 6695, 17661 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0021362", "MEDGEN:896878", "NCIT:C162304", "Orphanet:313920", "SCTID:716586009", "UMLS:C4274414" ], "synonyms": [ "EBV-associated gastric carcinoma", "EBVaGC" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC) is a rare form of gastric carcinoma (seen in approximately 10% of cases) with a male predominance, characterized by a latent EBV infection in gastric carcinoma cells, diffuse-type histology, a proximal location (in the body and cardia of the stomach) and a relatively favorable prognosis." }, "child_count": 0, "reference_id": "MONDO:0017784" }, { "id": 18536, "label": "hereditary gastric cancer", "isLeaf": false, "isRoot": false, "parents": [ 5714, 6695 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0021758", "MEDGEN:1843054", "Orphanet:423776", "UMLS:C5680075" ], "synonyms": [ "hereditary cancer of stomach", "hereditary gastric cancer" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "Hereditary gastric cancer refers to the occurrence of gastric cancer in a familial context and is described as two or more cases of gastric cancer in first or second degree relatives with at least one case diagnosed before the age of 50. Familial clustering is observed in 10% of all cases of gastric cancer, and includes hereditary diffuse gastric cancer (early onset diffuse-type gastric cancer), gastric adenocarcinoma and proximal polyposis of the stomach and familial intestinal gastric cancer (familial clustering of intestinal type gastric adenocarcinoma). Hereditary gastric cancer can also occur in other hereditary cancer syndromes such as Lynch syndrome, Li-Fraumeni syndrome, familial adenomatous polyposis and juvenile polyposis syndrome." }, "child_count": 8, "reference_id": "MONDO:0018502" }, { "id": 18537, "label": "carcinoma of stomach, salivary gland type", "isLeaf": true, "isRoot": false, "parents": [ 6695 ], "type_id": 0, "properties": { "xrefs": [ "Orphanet:423781" ], "synonyms": [ "gastric carcinoma, salivary gland type" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ] }, "child_count": 0, "reference_id": "MONDO:0018503" }, { "id": 18538, "label": "undifferentiated carcinoma of stomach", "isLeaf": true, "isRoot": false, "parents": [ 6695, 7257 ], "type_id": 0, "properties": { "xrefs": [ "GARD:0021759", "MEDGEN:237029", "NCIT:C5476", "ONCOTREE:USTAD", "Orphanet:423786", "SCTID:766757006", "UMLS:C1336858" ], "synonyms": [ "Gastric undifferentiated carcinoma", "anaplastic carcinoma of stomach", "anaplastic carcinoma of the stomach", "anaplastic gastric carcinoma", "stomach undifferentiated carcinoma", "undifferentiated carcinoma of stomach", "undifferentiated carcinoma of the stomach", "undifferentiated gastric (stomach) cancer", "undifferentiated gastric carcinoma", "undifferentiated stomach adenocarcinoma" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A carcinoma that arises from the stomach and is characterized by the absence of microscopic features of glandular or squamous differentiation." }, "child_count": 0, "reference_id": "MONDO:0018504" } ], "roots": [ { "id": 3312, "label": "gastric cancer" }, { "id": 7738, "label": "digestive system carcinoma" } ] }