{
  "id": 6700,
  "label": "mucinous adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004957",
  "properties": {
    "xrefs": [
      "DOID:3030",
      "EFO:0000197",
      "ICDO:8480/3",
      "MEDGEN:2844",
      "MESH:D002288",
      "NCIT:C26712",
      "ONCOTREE:CEMU",
      "UMLS:C0007130",
      "icd11.foundation:529352875"
    ],
    "synonyms": [
      "adenocarcinoma, mucinous, malignant",
      "colloid adenocarcinoma",
      "colloid carcinoma",
      "gelatinous adenocarcinoma",
      "gelatinous carcinoma",
      "mucin-producing adenocarcinoma (morphologic abnormality)",
      "mucinous adenocarcinoma",
      "mucinous carcinoma",
      "mucinuos carcinoma",
      "mucoid adenocarcinoma",
      "mucoid carcinoma",
      "mucous adenocarcinoma",
      "mucous carcinoma",
      "CEMU"
    ],
    "definition": "An invasive adenocarcinoma composed of malignant glandular cells which contain intracytoplasmic mucin. Often, the infiltrating glandular structures are associated with mucoid stromal formation. It may arise from the large and small intestine, appendix, stomach, lung, ovary, breast, corpus uteri, cervix, vagina, and salivary gland."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 17,
  "parents": [
    {
      "id": 6712,
      "label": "adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-0386",
          "DOID:299",
          "EFO:0000228",
          "ICDO:8140/3",
          "MEDGEN:122",
          "MESH:D000230",
          "NCIT:C2852",
          "ONCOTREE:ADNOS",
          "SCTID:443961001",
          "UMLS:C0001418"
        ],
        "synonyms": [
          "adenocarcinoma",
          "adenocarcinoma NOS (morphologic abnormality)",
          "adenocarcinoma, malignant",
          "adenocarcinoma, no subtype (morphologic abnormality)",
          "adenocarcinomas",
          "ADNOS"
        ],
        "definition": "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma."
      },
      "child_count": 128,
      "reference_id": "MONDO:0004970"
    },
    {
      "id": 20031,
      "label": "mucin-producing carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21367
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:87225",
          "NCIT:C27825",
          "UMLS:C0334368"
        ],
        "synonyms": [
          "mucin-producing carcinoma"
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0020596"
    }
  ],
  "children": [
    {
      "id": 4748,
      "label": "breast mucinous carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6698,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3610",
          "MEDGEN:235337",
          "NCIT:C9131",
          "ONCOTREE:IMMC",
          "SCTID:444712000",
          "UMLS:C1334807"
        ],
        "synonyms": [
          "breast mucinous carcinoma",
          "colloid breast carcinoma",
          "colloid carcinoma of breast",
          "colloid carcinoma of the breast",
          "infiltrating colloid breast carcinoma",
          "infiltrating mucinous breast carcinoma",
          "invasive colloid breast carcinoma",
          "invasive mucinous breast carcinoma",
          "mucinous breast cancer",
          "mucinous breast carcinoma",
          "mucinous carcinoma of breast",
          "mucinous carcinoma of the breast",
          "breast invasive mixed mucinous carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An invasive adenocarcinoma of the breast characterized by the presence of islands of small and uniform cells, surrounded by large amounts of mucin. Pure mucinous breast carcinomas generally have a favorable prognosis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002707"
    },
    {
      "id": 4775,
      "label": "extrahepatic bile duct mucinous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4714,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3698",
          "GARD:0023226",
          "MEDGEN:167830",
          "NCIT:C5846",
          "UMLS:C0861856"
        ],
        "synonyms": [
          "bile duct colloid carcinoma",
          "bile duct colloidal carcinoma",
          "bile duct mucinous adenocarcinoma",
          "colloid adenocarcinoma of bile duct",
          "colloid adenocarcinoma of extrahepatic bile duct",
          "colloid adenocarcinoma of the bile duct",
          "colloid adenocarcinoma of the extrahepatic bile duct",
          "colloid bile duct adenocarcinoma",
          "colloid bile duct carcinoma",
          "colloid carcinoma of bile duct",
          "colloid carcinoma of the bile duct",
          "colloid extrahepatic bile duct adenocarcinoma",
          "colloidal adenocarcinoma of bile duct",
          "colloidal adenocarcinoma of extrahepatic bile duct",
          "colloidal adenocarcinoma of the bile duct",
          "colloidal adenocarcinoma of the extrahepatic bile duct",
          "colloidal bile duct adenocarcinoma",
          "colloidal bile duct carcinoma",
          "colloidal carcinoma of bile duct",
          "colloidal carcinoma of the bile duct",
          "colloidal extrahepatic bile duct adenocarcinoma",
          "extrahepatic bile duct mucinous adenocarcinoma",
          "mucinous adenocarcinoma of bile duct",
          "mucinous adenocarcinoma of extrahepatic bile duct",
          "mucinous adenocarcinoma of the bile duct",
          "mucinous adenocarcinoma of the extrahepatic bile duct",
          "mucinous bile duct adenocarcinoma",
          "mucinous carcinoma of bile duct",
          "mucinous carcinoma of the bile duct",
          "mucinous extrahepatic bile duct adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the extrahepatic bile ducts. It is characterized by the presence of extracellular mucin that constitutes more than fifty-percent of the tumor."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002739"
    },
    {
      "id": 4778,
      "label": "cervical mucinous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6700,
        6877
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3701",
          "GARD:0023229",
          "MEDGEN:232048",
          "NCIT:C36095",
          "UMLS:C1332919"
        ],
        "synonyms": [
          "cervical mucinous adenocarcinoma",
          "uterine cervix mucinous adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A usually well to moderately differentiated cervical adenocarcinoma characterized by the presence of malignant glandular cells that contain significant amount of intracytoplasmic mucin."
      },
      "child_count": 12,
      "reference_id": "MONDO:0002742"
    },
    {
      "id": 4779,
      "label": "fallopian tube mucinous adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4780,
        4781,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3704",
          "GARD:0023230",
          "MEDGEN:274489",
          "NCIT:C40103",
          "UMLS:C1517119"
        ],
        "synonyms": [
          "fallopian tube mucinous adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An extremely rare adenocarcinoma that arises from the fallopian tube. It is characterized by the presence of neoplastic epithelial cells that contain intracytoplasmic mucin. The cases that have been reported are predominantly in situ mucinous adenocarcinomas."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002744"
    },
    {
      "id": 4782,
      "label": "endometrial mucinous adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6700,
        7120
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3707",
          "EFO:1000236",
          "MEDGEN:276939",
          "NCIT:C40144",
          "ONCOTREE:UMC",
          "UMLS:C1519859",
          "icd11.foundation:395055399"
        ],
        "synonyms": [
          "endometrial mucinous adenocarcinoma",
          "endometrium mucinous adenocarcinoma",
          "uterine corpus mucinous adenocarcinoma",
          "uterine mucinous carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary, usually low grade adenocarcinoma of the endometrium in which the majority of the malignant epithelial cells contain abundant intracytoplasmic mucin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002747"
    },
    {
      "id": 4783,
      "label": "rectum mucinous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4295,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3709",
          "MEDGEN:83537",
          "NCIT:C7973",
          "UMLS:C0279652"
        ],
        "synonyms": [
          "colloid adenocarcinoma of rectum",
          "colloid adenocarcinoma of the rectum",
          "colloidal adenocarcinoma of rectum",
          "colloidal adenocarcinoma of the rectum",
          "mucinous adenocarcinoma of rectum",
          "mucinous adenocarcinoma of the rectum",
          "rectal colloid adenocarcinoma",
          "rectal colloidal adenocarcinoma",
          "rectal mucinous adenocarcinoma",
          "rectum mucinous adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An invasive adenocarcinoma of the rectum characterized by the presence of pools of extracellular mucin. Malignant glandular epithelial cells are present in the mucin collections. Mucin constitutes more than 50% of the lesion."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002748"
    },
    {
      "id": 5029,
      "label": "mucoepidermoid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6700,
        8180
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:163",
          "DOID:4531",
          "GARD:0010671",
          "ICDO:8430/1",
          "ICDO:8430/3",
          "MEDGEN:61662",
          "MESH:D018277",
          "MESH:D018298",
          "NCIT:C3772",
          "ONCOTREE:MUCC",
          "UMLS:C0206694",
          "icd11.foundation:287052516"
        ],
        "synonyms": [
          "MEC",
          "mucoepidermoid carcinoma",
          "mucoepidermoid carcinoma (morphologic abnormality)",
          "mucoepidermoid tumor",
          "mucoepidermoid tumour",
          "MUCC",
          "mucoepidermoid tumors",
          "mucoepidermoid tumours",
          "tumor, mucoepidermoid",
          "tumors, mucoepidermoid"
        ],
        "definition": "A carcinoma morphologically characterized the presence of cuboidal mucous cells, goblet-like mucous cells, squamoid cells, cystic changes, and a fibrotic stromal formation. It can occur in several anatomic sites, including parotid gland, oral cavity, paranasal sinus, skin, breast, lung, larynx, and lacrimal ducts. It is classified as low or high grade."
      },
      "child_count": 24,
      "reference_id": "MONDO:0003036"
    },
    {
      "id": 5907,
      "label": "gallbladder mucinous adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6700,
        7768
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6998",
          "GARD:0023805",
          "MEDGEN:234292",
          "NCIT:C5744",
          "UMLS:C1333750"
        ],
        "synonyms": [
          "colloid carcinoma of gallbladder",
          "colloid carcinoma of the gallbladder",
          "colloidal carcinoma of gallbladder",
          "colloidal carcinoma of the gallbladder",
          "gall bladder mucinous adenocarcinoma",
          "gallbladder colloid carcinoma",
          "gallbladder colloidal carcinoma",
          "gallbladder mucinous adenocarcinoma",
          "mucinous carcinoma of gallbladder",
          "mucinous carcinoma of the gallbladder",
          "gallbladder mucinous carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the gallbladder. It is characterized by the presence of extracellular mucin that constitutes more than fifty-percent of the tumor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004067"
    },
    {
      "id": 6157,
      "label": "colloid carcinoma of the pancreas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6700,
        6905
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7717",
          "GARD:0027677",
          "MEDGEN:232082",
          "NCIT:C37214",
          "UMLS:C1333081"
        ],
        "synonyms": [
          "colloid carcinoma of the pancreas",
          "mucinous Noncystic carcinoma",
          "pancreatic mucinous Noncystic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An infiltrating pancreatic ductal adenocarcinoma, characterized by the presence of malignant cells floating in pools of mucin. It has a more favorable prognosis than the conventional infiltrating ductal adenocarcinoma. It often arises in association with intraductal pancreatic mucinous neoplasms and in some cases it may result in the development of pseudomyxoma peritonei."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004341"
    },
    {
      "id": 6745,
      "label": "colon mucinous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4386,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3029",
          "EFO:0000364",
          "MEDGEN:76007",
          "NCIT:C7966",
          "UMLS:C0279639"
        ],
        "synonyms": [
          "colloid adenocarcinoma of colon",
          "colloid adenocarcinoma of the colon",
          "colloid colon adenocarcinoma",
          "colloidal adenocarcinoma of colon",
          "colloidal adenocarcinoma of the colon",
          "colloidal colon adenocarcinoma",
          "colon colloid adenocarcinoma",
          "colon colloidal adenocarcinoma",
          "colon mucinous adenocarcinoma",
          "colonic colloid adenocarcinoma",
          "colonic colloidal adenocarcinoma",
          "colonic mucinous adenocarcinoma",
          "mucinous adenocarcinoma of colon",
          "mucinous adenocarcinoma of the colon",
          "mucinous colon adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An invasive adenocarcinoma of the colon characterized by the presence of pools of extracellular mucin. Malignant glandular epithelial cells are present in the mucin collections. Mucin constitutes more than 50% of the lesion."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005007"
    },
    {
      "id": 7244,
      "label": "ovarian mucinous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4787,
        6700,
        21318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3606",
          "EFO:0006462",
          "GARD:0021651",
          "MEDGEN:235418",
          "NCIT:C5243",
          "Orphanet:398961",
          "UMLS:C1335167",
          "icd11.foundation:869438441"
        ],
        "synonyms": [
          "mucinous adenocarcinoma of ovary",
          "mucinous adenocarcinoma of the ovary",
          "mucinous carcinoma of ovary",
          "mucinous carcinoma of the ovary",
          "ovarian mucinous adenocarcinoma",
          "ovarian mucinous carcinoma",
          "ovary mucinous adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An invasive adenocarcinoma that arises from the ovary and is characterized by the presence of malignant epithelial cells that contain intracytoplasmic mucin. There is cellular atypia, increased layering of cells, complexity of glands, and papillary formations."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005601"
    },
    {
      "id": 7469,
      "label": "mucinous cystadenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6700,
        7240
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3603",
          "EFO:0007378",
          "ICDO:8470/3",
          "MEDGEN:60211",
          "MESH:D018282",
          "NCIT:C3776",
          "UMLS:C0206699"
        ],
        "synonyms": [
          "Pseudomucinous adenocarcinoma",
          "Pseudomucinous cystadenocarcinoma",
          "mucinous cystadenocarcinoma",
          "mucinous cystadenocarcinoma (morphologic abnormality)",
          "mucinous cystadenocarcinoma NOS (morphologic abnormality)"
        ],
        "definition": "An invasive adenocarcinoma characterized by cystic changes and the presence of malignant glandular cells which contain intracytoplasmic mucin. It may arise from the ovary, pancreas, appendix, and lung."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005858"
    },
    {
      "id": 7647,
      "label": "acinar prostate mucinous adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4572,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3703",
          "EFO:1000065",
          "GARD:0027739",
          "MEDGEN:277536",
          "NCIT:C5537",
          "UMLS:C1335513"
        ],
        "synonyms": [
          "acinar colloid prostate adenocarcinoma",
          "colloid adenocarcinoma of prostate",
          "colloid adenocarcinoma of the prostate",
          "colloidal adenocarcinoma of prostate",
          "colloidal adenocarcinoma of the prostate",
          "colloidal prostate adenocarcinoma",
          "mucinous adenocarcinoma of prostate",
          "mucinous adenocarcinoma of the prostate",
          "prostate colloid adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A usually aggressive morphologic variant of acinar adenocarcinoma of the prostate gland characterized by the presence of lakes of extracellular mucin. This diagnosis applies when at least 25% of the resected tumor contains extracellular mucin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006067"
    },
    {
      "id": 7846,
      "label": "mucinous gastric adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6700,
        6770
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3716",
          "EFO:1000386",
          "GARD:0027748",
          "MEDGEN:235338",
          "NCIT:C5248",
          "ONCOTREE:MSTAD",
          "UMLS:C1334809"
        ],
        "synonyms": [
          "mucinous adenocarcinoma of stomach",
          "mucinous adenocarcinoma of the stomach",
          "mucinous gastric adenocarcinoma",
          "mucinous stomach adenocarcinoma",
          "stomach mucinous adenocarcinoma",
          "MSTAD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A variant of gastric adenocarcinoma with more than half of the tumor containing extracellular mucinous pools."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006309"
    },
    {
      "id": 21771,
      "label": "lung colloid adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6700,
        6791
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080303",
          "DOID:0080304",
          "GARD:0025501",
          "MEDGEN:313370",
          "NCIT:C45512",
          "UMLS:C1708776"
        ],
        "synonyms": [
          "lung colloid adenocarcinoma",
          "lung mucinous cystadenocarcinoma",
          "lung mucinous cystic tumor of borderline malignancy",
          "lung mucinous cystic tumour of borderline malignancy",
          "mucinous lung adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A morphologic variant of lung adenocarcinoma characterized by the presence of mucin pools containing islands of well differentiated adenocarcinoma cells."
      },
      "child_count": 4,
      "reference_id": "MONDO:0027772"
    },
    {
      "id": 25181,
      "label": "mucinous pancreas adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6700,
        7633
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080782",
          "GARD:0028069"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A pancreatic adenocarcinoma that derives from epithelial cells originating in glandular tissue, which produce mucin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850257"
    },
    {
      "id": 25185,
      "label": "salivary gland mucinous adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2972,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080800",
          "GARD:0028070",
          "MEDGEN:364330",
          "NCIT:C62193",
          "UMLS:C1882973"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A salivary gland carcinoma that is characterized by the presence of large pools of extracellular mucin in which clusters of malignant epithelial cells are found."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850273"
    }
  ],
  "roots": [
    {
      "id": 6712,
      "label": "adenocarcinoma"
    },
    {
      "id": 20031,
      "label": "mucin-producing carcinoma"
    }
  ]
}