{
  "id": 6720,
  "label": "asthma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004979",
  "properties": {
    "xrefs": [
      "DOID:2841",
      "HP:0002099",
      "ICD10CM:J45",
      "ICD10WHO:J45",
      "ICD9:493",
      "ICD9:493.81",
      "ICD9:493.9",
      "MEDGEN:2109",
      "MESH:D001249",
      "NCIT:C28397",
      "SCTID:31387002",
      "UMLS:C0004096",
      "icd11.foundation:1656445230"
    ],
    "synonyms": [
      "chronic obstructive asthma",
      "chronic obstructive asthma with acute exacerbation",
      "chronic obstructive asthma with status asthmaticus",
      "exercise induced asthma",
      "exercise-induced asthma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 3582,
      "label": "bronchial disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2809
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1176",
          "EFO:1002018",
          "ICD9:519.19",
          "MEDGEN:14233",
          "MESH:D001982",
          "NCIT:C34439",
          "SCTID:41427001",
          "UMLS:C0006261"
        ],
        "synonyms": [
          "bronchial disorder",
          "bronchospasm",
          "bronchus disease",
          "bronchus disease or disorder",
          "disease of bronchus",
          "disease or disorder of bronchus",
          "disorder of bronchus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disease involving the bronchus."
      },
      "child_count": 6,
      "reference_id": "MONDO:0001358"
    }
  ],
  "children": [
    {
      "id": 3701,
      "label": "cough variant asthma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12323",
          "ICD10CM:J45.991",
          "ICD9:493.82",
          "MEDGEN:675053",
          "SCTID:409663006",
          "UMLS:C0694548",
          "icd11.foundation:1466639844"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An asthma that is characterized by chronic nonproductive cough without shortness of breath."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001491"
    },
    {
      "id": 6535,
      "label": "intrinsic asthma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9360",
          "ICD9:493.1",
          "MEDGEN:510123",
          "SCTID:266361008",
          "UMLS:C0155880"
        ],
        "synonyms": [
          "non-allergic asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An asthma that is triggered by factors not related to allergies such as anxiety, stress, exercise, cold air, dry air, hyperventilation, smoke, viruses, chemical irritants, autonomic imbalance, hormonal deficiencies and psychogenic influences. It is characterized by airway obstruction and inflammation that is at least partially reversible with medication. The symptoms include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness."
      },
      "child_count": 3,
      "reference_id": "MONDO:0004765"
    },
    {
      "id": 6536,
      "label": "status asthmaticus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9362",
          "EFO:0008590",
          "ICD10WHO:J46",
          "ICD9:493.91",
          "MEDGEN:11584",
          "MESH:D013224",
          "NCIT:C122577",
          "SCTID:708090002",
          "UMLS:C0038218"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An acute exacerbation of asthma, characterized by inadequate response to initial bronchodilators."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004766"
    },
    {
      "id": 6551,
      "label": "allergic asthma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3133,
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9415",
          "ICD9:493.0",
          "MEDGEN:102343",
          "SCTID:389145006",
          "UMLS:C0155877",
          "icd11.foundation:1870104478"
        ],
        "synonyms": [
          "allergic form of asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A asthma with a basis in a pathological type I hypersensitivity reaction."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004784"
    },
    {
      "id": 7081,
      "label": "childhood onset asthma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080815",
          "MEDGEN:538550",
          "SCTID:233678006",
          "UMLS:C0264408"
        ],
        "synonyms": [
          "asthma of childhood",
          "childhood asthma",
          "paediatric asthma",
          "pediatric asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Asthma that starts in childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005405"
    },
    {
      "id": 20960,
      "label": "occupational asthma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6720,
        20956
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080820",
          "MEDGEN:452342",
          "MESH:D059366",
          "SCTID:57607007",
          "UMLS:C0264423"
        ],
        "synonyms": [
          "Asthma, Occupational",
          "Asthmas, Occupational",
          "Industrial asthma",
          "Occupational Asthma",
          "Occupational Asthmas",
          "Occupational asthma",
          "industrial asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Asthma attacks caused, triggered, or exacerbated by OCCUPATIONAL EXPOSURE."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022742"
    },
    {
      "id": 25187,
      "label": "chronic asthma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080809",
          "MEDGEN:1843404",
          "UMLS:C0877430"
        ],
        "synonyms": [
          "adult-onset severe asthma",
          "persistent mild asthma",
          "persistent moderate asthma",
          "persistent severe asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An asthma that is characterized by the development of persistent airway inflammation and recurrent attacks of breathlessness and wheezing, which vary in severity and frequency."
      },
      "child_count": 5,
      "reference_id": "MONDO:0850282"
    },
    {
      "id": 25188,
      "label": "acute asthma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6720
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080810",
          "MEDGEN:578946",
          "UMLS:C0349790"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An asthma that is characterized by severe and sudden onset of increasing wheezing, airways closing, smooth muscle contraction, mucus plugging and lower airway edema that may be reversible upon treatment."
      },
      "child_count": 1,
      "reference_id": "MONDO:0850283"
    }
  ],
  "roots": [
    {
      "id": 3582,
      "label": "bronchial disorder"
    }
  ]
}