{
  "id": 6732,
  "label": "minimally invasive lung adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0004991",
  "properties": {
    "xrefs": [
      "DOID:4926",
      "EFO:0000308",
      "GARD:0024141",
      "ICD9:162.9",
      "ICDO:8250/3",
      "ICDO:8251/3",
      "MEDGEN:2871",
      "MESH:D002282",
      "NCIT:C2923",
      "SCTID:373627005",
      "UMLS:C0007120"
    ],
    "synonyms": [
      "BAC",
      "bac",
      "bronchioalveolar adenocarcinoma of lung",
      "bronchioalveolar adenocarcinoma of the lung",
      "bronchioalveolar lung carcinoma",
      "bronchiolo-alveolar carcinoma of lung",
      "bronchiolo-alveolar carcinoma of the lung",
      "bronchiolo-alveolar lung carcinoma",
      "bronchioloalveolar adenocarcinoma of lung",
      "bronchioloalveolar adenocarcinoma of the lung",
      "bronchioloalveolar carcinoma",
      "bronchioloalveolar lung adenocarcinoma",
      "carcinoma, bronchioloalveolar, malignant",
      "minimally invasive lung adenocarcinoma",
      "bronchiolo-alveolar adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A solitary adenocarcinoma arising from the lung measuring 3 cm or less. It is characterized by a predominantly lepidic pattern and 5 mm or less invasion in greatest dimension. It is usually a non-mucinous adenocarcinoma, but rarely may be mucinous."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6791,
      "label": "lung adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6944
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3910",
          "EFO:0000571",
          "MEDGEN:57744",
          "MESH:C538231",
          "NCIT:C3512",
          "ONCOTREE:LUAD",
          "Orphanet:415268",
          "SCTID:254626006",
          "UMLS:C0152013"
        ],
        "synonyms": [
          "adenocarcinoma of lung",
          "adenocarcinoma of the lung",
          "lung adenocarcinoma",
          "non-small cell lung adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005061"
    }
  ],
  "children": [
    {
      "id": 3173,
      "label": "mixed mucinous and nonmucinous bronchioloalveolar adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6732
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080184",
          "GARD:0022840",
          "ICDO:8254/3",
          "MEDGEN:220410",
          "NCIT:C7270",
          "UMLS:C1266036"
        ],
        "synonyms": [
          "indeterminate bronchioloalveolar carcinoma",
          "mixed mucinous and non-mucinous bronchioloalveolar carcinoma",
          "mixed mucinous and non-mucinous bronchioloalveolar lung carcinoma",
          "mixed mucinous and non-mucinous bronchoalveolar lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare morphologic variant of bronchiolo-alveolar lung carcinoma characterized by the presence of both mucin and non-mucin producing cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000893"
    },
    {
      "id": 3174,
      "label": "mucinous bronchioloalveolar adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6732,
        21771
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080185",
          "GARD:0022841",
          "MEDGEN:1627584",
          "UMLS:C2200125"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A bronchiolo-alveolar adenocarcinoma that is characterized by a tumor cells containing abundant mucin in their cytoplasm and composed of tall columnar cells growing along alveolar walls without stromal invasion."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000894"
    },
    {
      "id": 3175,
      "label": "nonmucinous bronchioloalveolar adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6732
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080186",
          "GARD:0022842",
          "MEDGEN:266089",
          "NCIT:C7269",
          "UMLS:C1266034"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A bronchiolo-alveolar adenocarcinoma that is characterized by cells with cuboidal or columnar morphology with eosinophilic or clear cytoplasm and shows Clara cell or type 2 pneumocyte differentiation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000895"
    }
  ],
  "roots": [
    {
      "id": 6791,
      "label": "lung adenocarcinoma"
    }
  ]
}