{
  "id": 6748,
  "label": "coronary artery disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005010",
  "properties": {
    "xrefs": [
      "DOID:3393",
      "EFO:0001645",
      "ICD9:410-414",
      "ICD9:414.0",
      "ICD9:414.9",
      "MEDGEN:365486",
      "MESH:D003324",
      "NCIT:C26732",
      "SCTID:414024009",
      "UMLS:C1956346",
      "icd11.foundation:1059873720"
    ],
    "synonyms": [
      "CAD",
      "CHD (coronary heart disease)",
      "coronary artery disease",
      "coronary artery disease or disorder",
      "coronary disease",
      "coronary heart disease",
      "disease of coronary artery",
      "disease or disorder of coronary artery",
      "disorder of coronary artery",
      "coronary arteriosclerosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 12,
  "parents": [
    {
      "id": 2933,
      "label": "arterial disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050828",
          "ICD9:447.8",
          "ICD9:447.9",
          "MEDGEN:208875",
          "NCIT:C35317",
          "SCTID:359557001",
          "UMLS:C0852949"
        ],
        "synonyms": [
          "arterial disease",
          "arterial disorder",
          "arteriopathy",
          "artery disease",
          "artery disease or disorder",
          "disease of artery",
          "disease or disorder of artery",
          "disorder of artery"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An impairment of the structure or function of the blood vessels which carry blood away from the heart."
      },
      "child_count": 30,
      "reference_id": "MONDO:0000473"
    },
    {
      "id": 6967,
      "label": "heart disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:114",
          "EFO:0003777",
          "ICD9:429.89",
          "ICD9:429.9",
          "ICD9:V47.2",
          "MEDGEN:5458",
          "MESH:D006331",
          "NCIT:C3079",
          "SCTID:56265001",
          "UMLS:C0018799",
          "icd11.foundation:1512587470"
        ],
        "synonyms": [
          "cardiac disease",
          "disease of heart",
          "disease or disorder of heart",
          "disorder of heart",
          "disorder of heart/pericardium",
          "heart disease",
          "heart disease or disorder",
          "heart disorder",
          "heart trouble",
          "heart/pericardial disease",
          "heart/pericardial disease or disorder",
          "heart/pericardial disorder",
          "heart/pericardial trouble"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the heart and/or pericardium."
      },
      "child_count": 34,
      "reference_id": "MONDO:0005267"
    }
  ],
  "children": [
    {
      "id": 7040,
      "label": "coronary vasospasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6748
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11840",
          "EFO:0004225",
          "ICD9:413.9",
          "MEDGEN:3626",
          "MESH:D003329",
          "SCTID:23687008",
          "UMLS:C0010073"
        ],
        "synonyms": [
          "coronary artery vasospasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Sudden coronary artery smooth muscle contraction leading to lumen constriction and decreased blood flow."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005356"
    },
    {
      "id": 7103,
      "label": "postoperative ventricular dysfunction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6748,
        23501
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Postoperative ventricular dysfunction (VnD) occurs in 9-20% of coronary artery bypass graft (CABG) surgical patients and is associated with increased postoperative morbidity and mortality."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005436"
    },
    {
      "id": 8175,
      "label": "coronary aneurysm",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6748
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3362",
          "EFO:1000881",
          "HP:0030882",
          "ICD9:414.11",
          "MEDGEN:3622",
          "MESH:D003323",
          "MedDRA:10002348",
          "SCTID:50570003",
          "UMLS:C0010051",
          "icd11.foundation:777924269"
        ],
        "synonyms": [
          "aneurysm of coronary vessels",
          "aneurysmal lesion of coronary artery",
          "arteriovenous aneurysm of coronary vessels",
          "coronary artery aneurysm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Abnormal balloon- or sac-like dilatation in the wall of coronary vessels. Most coronary aneurysms are due to coronary atherosclerosis, and the rest are due to inflammatory diseases, such as kawasaki disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006714"
    },
    {
      "id": 8176,
      "label": "coronary stenosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6748
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4248",
          "MEDGEN:66859",
          "MESH:D023921",
          "MedDRA:10011089",
          "NANDO:2200246",
          "SCTID:233970002",
          "UMLS:C0242231"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Narrowing of the coronary artery lumen diameter."
      },
      "child_count": 1,
      "reference_id": "MONDO:0006715"
    },
    {
      "id": 8177,
      "label": "coronary thrombosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        6748
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11847",
          "EFO:1000883",
          "ICD10CM:I22",
          "MEDGEN:3625",
          "MESH:D003328",
          "MedDRA:10011108",
          "SCTID:398274000",
          "UMLS:C0010072"
        ],
        "synonyms": [
          "coronary vessel thrombotic disease",
          "thrombotic disease of coronary vessel"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006716"
    },
    {
      "id": 8253,
      "label": "intermediate coronary syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6748
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8805",
          "EFO:1000985",
          "ICD10CM:I20.0",
          "ICD9:411.1",
          "MEDGEN:296",
          "MESH:D000789",
          "MedDRA:10022554",
          "UMLS:C0002965",
          "icd11.foundation:253490233"
        ],
        "synonyms": [
          "Preinfarction angina",
          "angina at rest",
          "anginal chest pain at rest",
          "impending infarction",
          "unstable angina",
          "worsening angina"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Angina pectoris (or equivalent type of ischemic discomfort) which has recently changed in frequency, duration, intensity, or occurs at rest."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006805"
    },
    {
      "id": 13082,
      "label": "coronary artery disease, autosomal dominant, 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6748,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:330802",
          "MESH:C564258",
          "OMIM:608320",
          "UMLS:C1842247"
        ],
        "synonyms": [
          "MEF2A coronary artery disease",
          "coronary artery disease caused by mutation in MEF2A",
          "coronary artery disease, autosomal dominant, 1",
          "coronary artery disease, autosomal dominant, type 1",
          "ADCAD1",
          "coronary artery disease with myocardial infarction"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012011"
    },
    {
      "id": 13633,
      "label": "coronary artery disease, autosomal dominant 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6748,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:370259",
          "MESH:C567045",
          "OMIM:610947",
          "UMLS:C1970440"
        ],
        "synonyms": [
          "LRP6 coronary artery disease",
          "coronary artery disease caused by mutation in LRP6",
          "coronary artery disease, autosomal dominant 2",
          "coronary artery disease, autosomal dominant type 2",
          "coronary artery disease, autosomal dominant, 2",
          "ADCAD2"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012586"
    },
    {
      "id": 16114,
      "label": "coronary artery congenital malformation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6748,
        7116,
        19327
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11843",
          "GARD:0001534",
          "ICD9:746.85",
          "MEDGEN:1612789",
          "MedDRA:10061060",
          "Orphanet:1081",
          "SCTID:28574005",
          "UMLS:C4531298",
          "icd11.foundation:902783759"
        ],
        "synonyms": [
          "congenital anomaly of coronary artery",
          "congenital coronary artery anomaly",
          "coronary artery abnormality [ambiguous]",
          "coronary artery anomaly",
          "coronary artery anomaly, congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A coronary artery disorder characterized by abnormal origin, course, or structure of one or more coronary arteries present at birth."
      },
      "child_count": 27,
      "reference_id": "MONDO:0015203"
    },
    {
      "id": 20713,
      "label": "coronary atherosclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6748,
        7003
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0061139",
          "ICD9:414.00",
          "MEDGEN:3623",
          "NCIT:C35505",
          "SCTID:443502000",
          "UMLS:C0010054",
          "icd11.foundation:1280712786"
        ],
        "synonyms": [
          "atherosclerosis of coronary artery",
          "arteriosclerosis disorder of coronary artery",
          "coronary artery arteriosclerosis (disease)",
          "coronary artery arteriosclerosis disorder",
          "coronary atherosclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Atherosclerosis of the coronary vasculature."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021661"
    },
    {
      "id": 25214,
      "label": "nonobstructive coronary artery disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6748
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080938"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A coronary artery disease that is characterized by atherosclerotic plaque that would not be expected to obstruct blood flow or result in anginal symptoms and stenosis of coronary artery less than 50 percent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850371"
    },
    {
      "id": 26412,
      "label": "fibromuscular dysplasia of the coronary arteries",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6748,
        8215,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:698059"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0980999"
    }
  ],
  "roots": [
    {
      "id": 2933,
      "label": "arterial disorder"
    },
    {
      "id": 6967,
      "label": "heart disorder"
    }
  ]
}