{
  "id": 6749,
  "label": "Crohn disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005011",
  "properties": {
    "xrefs": [
      "DOID:8778",
      "EFO:0000384",
      "ICD10CM:K50",
      "ICD9:555.1",
      "MEDGEN:3664",
      "MESH:D003424",
      "NANDO:1200444",
      "NANDO:1200446",
      "NANDO:2200921",
      "NCIT:C2965",
      "Orphanet:206",
      "SCTID:7620006",
      "UMLS:C0010346",
      "icd11.foundation:1267652425"
    ],
    "synonyms": [
      "Crohn disease",
      "Crohn's disease",
      "Crohn's disease of large bowel",
      "paediatric Crohn's disease",
      "pediatric Crohn's disease",
      "regional enteritis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6965,
      "label": "inflammatory bowel disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6756,
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050589",
          "EFO:0003767",
          "ICD9:558.9",
          "MEDGEN:43877",
          "MESH:D015212",
          "NANDO:2100259",
          "NCIT:C3138",
          "OMIMPS:266600",
          "SCTID:24526004",
          "UMLS:C0021390"
        ],
        "synonyms": [
          "IBD",
          "autoimmune bowel disorder",
          "inflammatory bowel disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type."
      },
      "child_count": 120,
      "reference_id": "MONDO:0005265"
    }
  ],
  "children": [
    {
      "id": 7185,
      "label": "Crohn's colitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6749,
        21545
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060192",
          "EFO:0005622",
          "MEDGEN:57618",
          "NANDO:1200446",
          "NCIT:C35211",
          "UMLS:C0156147"
        ],
        "synonyms": [
          "Crohn colitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Crohn's disease affecting the colon."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005532"
    },
    {
      "id": 7188,
      "label": "oral Crohn disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6749,
        8301
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:585601",
          "SCTID:196578009",
          "UMLS:C0399497"
        ],
        "synonyms": [
          "oral Crohn's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Crohn's disease affecting the mouth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005535"
    },
    {
      "id": 7190,
      "label": "perianal Crohn disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6749,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005627",
          "MEDGEN:574362",
          "SCTID:235796008",
          "UMLS:C0341395",
          "icd11.foundation:464644598"
        ],
        "synonyms": [
          "perianal Crohn's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A Crohn disease involving a pathogenic inflammatory response in the anal region."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005537"
    },
    {
      "id": 7192,
      "label": "small bowel Crohn disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6749,
        23231
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005629",
          "MEDGEN:57617",
          "NANDO:1200445",
          "UMLS:C0156146"
        ],
        "synonyms": [
          "small bowel Crohn's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A Crohn disease involving a pathogenic inflammatory response in the small intestine."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005539"
    },
    {
      "id": 21051,
      "label": "Crohn disease of the esophagus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3630,
        6749
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:574175",
          "UMLS:C0341116"
        ],
        "synonyms": [
          "Crohn's disease of the esophagus",
          "Crohn's disease of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A Crohn disease involving a pathogenic inflammatory response in the esophagus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022901"
    }
  ],
  "roots": [
    {
      "id": 6965,
      "label": "inflammatory bowel disease"
    }
  ]
}