{
  "id": 6754,
  "label": "diffuse gastric adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005017",
  "properties": {
    "xrefs": [
      "DOID:6217",
      "EFO:0000402",
      "GARD:0027712",
      "MEDGEN:79019",
      "NCIT:C9159",
      "ONCOTREE:DSTAD",
      "UMLS:C0279635"
    ],
    "synonyms": [
      "adenocarcinoma of linitis plastica type",
      "adenocarcinoma of the linitis plastica type",
      "carcinoma, diffuse type",
      "carcinoma, diffuse type (morphologic abnormality)",
      "diffuse adenocarcinoma of stomach",
      "diffuse adenocarcinoma of the stomach",
      "diffuse gastric adenocarcinoma",
      "diffuse stomach adenocarcinoma",
      "gastric diffuse adenocarcinoma",
      "stomach diffuse type adenocarcinoma",
      "diffuse type stomach adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "An adenocarcinoma arising from the stomach. Microscopically, it is characterized by the presence of a diffuse infiltrate, composed of individual adenocarcinoma cells or groups of adenocarcinoma cells in a fibrous or mucoid stroma. Many cells contain mucin droplets, producing a signet-ring configuration."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6770,
      "label": "gastric adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6695,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3717",
          "EFO:0000503",
          "GARD:0027713",
          "MEDGEN:82961",
          "NCIT:C4004",
          "ONCOTREE:STAD",
          "Orphanet:464463",
          "SCTID:408647009",
          "UMLS:C0278701",
          "icd11.foundation:1855471719"
        ],
        "synonyms": [
          "adenocarcinoma - stomach",
          "adenocarcinoma of stomach",
          "adenocarcinoma of the stomach",
          "gastric (stomach) adenocarcinoma",
          "gastric adenocarcinoma",
          "stomach adenocarcinoma",
          "STAD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the stomach"
      },
      "child_count": 18,
      "reference_id": "MONDO:0005036"
    },
    {
      "id": 20704,
      "label": "diffuse type adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8145/3",
          "MEDGEN:87207",
          "NCIT:C4127",
          "UMLS:C0334280"
        ],
        "synonyms": [
          "diffuse type adenocarcinoma",
          "diffuse type carcinoma"
        ],
        "definition": "An adenocarcinoma characterized by the presence of a diffuse cellular infiltrate which is composed of poorly cohesive cells with minimal or no glandular formations. Representative example is the gastric diffuse adenocarcinoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0021652"
    }
  ],
  "children": [
    {
      "id": 9010,
      "label": "hereditary diffuse gastric adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6754,
        18536
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080764",
          "GARD:0010900",
          "MEDGEN:310839",
          "NCIT:C43295",
          "Orphanet:26106",
          "SCTID:716859000",
          "UMLS:C1708349"
        ],
        "synonyms": [
          "FDGC",
          "HDGC",
          "familial diffuse cancer of stomach",
          "familial diffuse gastric cancer",
          "hereditary diffuse cancer of stomach",
          "hereditary diffuse gastric adenocarcinoma",
          "hereditary diffuse gastric cancer",
          "diffuse gastric cancer",
          "signet cell adenocarcinoma",
          "signet ring cell gastric carcinoma",
          "signet ring gastric carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An autosomal dominant inherited adenocarcinoma that arises from the gastric mucosa and is characterized by the presence of poorly cohesive malignant cells and absence of glandular formations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007648"
    },
    {
      "id": 18326,
      "label": "gastric linitis plastica",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6754,
        23540
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4023",
          "GARD:0018822",
          "ICDO:8142/3",
          "MEDGEN:7345",
          "MESH:D008039",
          "NCIT:C3190",
          "Orphanet:36273",
          "SCTID:721629005",
          "UMLS:C0023743",
          "icd11.foundation:1165754036"
        ],
        "synonyms": [
          "Borrmann gastric cancer type 4",
          "leather-bottle stomach",
          "linitis plastica",
          "linitis plastica (morphologic abnormality)",
          "linitis plastica of the stomach"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Gastric linitis plastica (gastric LP) is a malignant, diffuse, infiltrative gastric adenocarcinoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018184"
    }
  ],
  "roots": [
    {
      "id": 6770,
      "label": "gastric adenocarcinoma"
    },
    {
      "id": 20704,
      "label": "diffuse type adenocarcinoma"
    }
  ]
}