{
  "id": 6759,
  "label": "endocarditis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005025",
  "properties": {
    "xrefs": [
      "DOID:10314",
      "EFO:0000465",
      "HP:0100584",
      "ICD9:421.9",
      "ICD9:424.99",
      "MEDGEN:4940",
      "MESH:D004696",
      "NCIT:C34582",
      "SCTID:56819008",
      "UMLS:C0014118"
    ],
    "synonyms": [
      "endocarditis",
      "endocarditis (disease)",
      "endocardium inflammation",
      "inflammation of endocardium"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Inflammation of the endocardium."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 2931,
      "label": "endocardium disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050825",
          "MEDGEN:678520",
          "SCTID:123596001",
          "UMLS:C0854140"
        ],
        "synonyms": [
          "disease of endocardium",
          "disease or disorder of endocardium",
          "disorder of endocardium",
          "endocardial disease",
          "endocardium disease",
          "endocardium disease or disorder",
          "endocardiopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the endocardium."
      },
      "child_count": 3,
      "reference_id": "MONDO:0000470"
    },
    {
      "id": 21547,
      "label": "inflammation of heart layer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:429.89",
          "MEDGEN:163689",
          "SCTID:399617002",
          "UMLS:C0869523"
        ],
        "synonyms": [
          "carditis",
          "heart layer inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An inflammatory disease involving a pathogenic inflammatory response in the heart layer."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024636"
    }
  ],
  "children": [
    {
      "id": 2995,
      "label": "infective endocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6759,
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060000",
          "GARD:0006337",
          "ICD9:136.9",
          "MEDGEN:323818",
          "NCIT:C78265",
          "NORD:1091",
          "Orphanet:570762",
          "SCTID:233850007",
          "UMLS:C1541923",
          "icd11.foundation:512128824"
        ],
        "synonyms": [
          "endocarditis infective",
          "endocarditis, infective"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Infective endocarditis (IE) is an infection of the inner lining of the heart chambers (endocardium) and valves. This condition is sometimes called 'endocarditis,' although it is important to distinguish it from non-infective endocarditis. IE is caused bybacteria, fungi, or other germs invading the bloodstream and attaching to the heart. IE can damagethe heart and cause serious and sometimes fatal complications. It can develop quickly or slowly depending on what type of germ is causing it and whether there is an underlying heart problem. Common symptoms of IE are fever and other flu-like symptoms, but signs and symptoms can vary. It can also cause problems in many other parts of the body besides the heart. IE is typically treated with antibiotics for several weeks; some individuals may need heart surgery to repair or replace heart valves or remove infected heart tissue."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000565"
    },
    {
      "id": 3021,
      "label": "marantic endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3150,
        3738,
        6759
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060068",
          "GARD:0022812",
          "MEDGEN:452215",
          "MESH:D059905",
          "SCTID:57181007",
          "UMLS:C0221390"
        ],
        "synonyms": [
          "nonbacterial thrombotic endocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Formation of a non-infectious thrombus, referred to as vegetation, on previously undamaged endocardium. It usually occurs as a complication of connective-tissue diseases and cancers because of the associated hypercoagulable state (see thrombophilia)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000610"
    },
    {
      "id": 25177,
      "label": "Libman-Sacks endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3017,
        6759
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080740",
          "MEDGEN:69175",
          "UMLS:C0242380"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "An endocarditis that is characterized by Libman-Sacks vegetations, is common in patients with systemic lupus erythematosus and is commonly complicated with embolic cerebrovascular disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850223"
    }
  ],
  "roots": [
    {
      "id": 2931,
      "label": "endocardium disorder"
    },
    {
      "id": 21547,
      "label": "inflammation of heart layer"
    }
  ]
}