{
  "id": 6760,
  "label": "endometrioid adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005026",
  "properties": {
    "xrefs": [
      "EFO:0000466",
      "ICDO:8380/3",
      "MEDGEN:293976",
      "NCIT:C3769",
      "UMLS:C1569637"
    ],
    "synonyms": [
      "endometrioid adenocarcinoma",
      "endometrioid carcinoma",
      "endometrioid carcinoma of female reproductive system",
      "endometrioid carcinoma of the female reproductive system",
      "female reproductive endometrioid carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "An adenocarcinoma characterized by the presence of malignant glandular epithelial cells resembling endometrial cells. It can arise from the uterine body, ovary, fallopian tube, cervix, vagina, and uterine ligament."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 3637,
      "label": "female reproductive organ cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4279,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:120",
          "EFO:1001331",
          "ICD10CM:C51-C58",
          "ICD9:184",
          "MEDGEN:195944",
          "NCIT:C4913",
          "SCTID:126907002",
          "UMLS:C0699889"
        ],
        "synonyms": [
          "cancer of female reproductive organ",
          "female reproductive cancer",
          "female reproductive organ cancer",
          "gynecologic cancer",
          "malignant female reproductive organ neoplasm",
          "malignant female reproductive system neoplasm",
          "malignant female reproductive system tumor",
          "malignant female reproductive system tumour",
          "malignant gynecologic neoplasm",
          "malignant gynecologic tumor",
          "malignant gynecologic tumour",
          "malignant neoplasm of female reproductive organ",
          "malignant neoplasm of female reproductive system",
          "malignant neoplasm of the female reproductive system",
          "malignant tumor of female reproductive system",
          "malignant tumor of the female reproductive system",
          "malignant tumour of female reproductive system",
          "malignant tumour of the female reproductive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumor, and gestational choriocarcinoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0001416"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-0386",
          "DOID:299",
          "EFO:0000228",
          "ICDO:8140/3",
          "MEDGEN:122",
          "MESH:D000230",
          "NCIT:C2852",
          "ONCOTREE:ADNOS",
          "SCTID:443961001",
          "UMLS:C0001418"
        ],
        "synonyms": [
          "adenocarcinoma",
          "adenocarcinoma NOS (morphologic abnormality)",
          "adenocarcinoma, malignant",
          "adenocarcinoma, no subtype (morphologic abnormality)",
          "adenocarcinomas",
          "ADNOS"
        ],
        "definition": "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma."
      },
      "child_count": 128,
      "reference_id": "MONDO:0004970"
    }
  ],
  "children": [
    {
      "id": 5551,
      "label": "cervical endometrioid adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6760,
        6877
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5830",
          "EFO:1000164",
          "GARD:0023611",
          "MEDGEN:272450",
          "NCIT:C6343",
          "ONCOTREE:CEEN",
          "UMLS:C1332913"
        ],
        "synonyms": [
          "cervical endometrioid adenocarcinoma",
          "cervical endometrioid carcinoma",
          "cervix endometrioid adenocarcinoma",
          "cervix endometrioid carcinoma",
          "cervix uteri endometrioid adenocarcinoma",
          "cervix uteri endometrioid carcinoma",
          "endometrioid adenocarcinoma of cervix",
          "endometrioid adenocarcinoma of cervix uteri",
          "endometrioid adenocarcinoma of the cervix",
          "endometrioid adenocarcinoma of the cervix uteri",
          "endometrioid adenocarcinoma of the uterine cervix",
          "endometrioid adenocarcinoma of uterine cervix",
          "endometrioid carcinoma of cervix",
          "endometrioid carcinoma of cervix uteri",
          "endometrioid carcinoma of the cervix",
          "endometrioid carcinoma of the cervix uteri",
          "endometrioid carcinoma of the uterine cervix",
          "endometrioid carcinoma of uterine cervix",
          "uterine cervix endometrioid adenocarcinoma",
          "uterine cervix endometrioid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A cervical adenocarcinoma with the histologic characteristics of the endometrioid adenocarcinoma of the endometrium."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003665"
    },
    {
      "id": 5552,
      "label": "fallopian tube endometrioid adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4781,
        6760
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5831",
          "GARD:0023612",
          "MEDGEN:232185",
          "NCIT:C6279",
          "UMLS:C1333592"
        ],
        "synonyms": [
          "endometrioid adenocarcinoma of fallopian tube",
          "endometrioid adenocarcinoma of the fallopian tube",
          "endometrioid carcinoma of fallopian tube",
          "endometrioid carcinoma of the fallopian tube",
          "fallopian tube endometrioid adenocarcinoma",
          "fallopian tube endometrioid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the fallopian tube and resembles the endometrioid adenocarcinoma of the uterus. It usually has a favorable prognosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003666"
    },
    {
      "id": 6704,
      "label": "stage I endometrioid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6760
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb).It is the result of the abnormal growth of cells that have the ability to invade or spread to other parts of the body. The first sign is most often vaginal bleeding not associated with a menstrual period. Other symptoms include pain with urination or sexual intercourse, or pelvic pain. Endometrial cancer occurs most commonly after menopause. In stage I, the cancer is only growing in the body of the uterus. It may also be growing into the glands of the cervix, but is not growing into the supporting connective tissue of the cervix."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004961"
    },
    {
      "id": 6705,
      "label": "stage II endometrioid carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6760
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Endometrial carcinoma is a carcinoma that arises from the endometrium (the lining of the uterus or womb). It is the result of the abnormal growth of cells that have the ability to invade or spread to other parts of the body. The first sign is most often vaginal bleeding not associated with a menstrual period. Other symptoms include pain with urination or sexual intercourse, or pelvic pain. Endometrial cancer occurs most commonly after menopause. In stage II the cancer has spread from the body of the uterus and is growing into the supporting connective tissue of the cervix (called the cervical stroma). The cancer has spread into connective tissue of the cervix, but has not spread outside the uterus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004962"
    },
    {
      "id": 7748,
      "label": "endometrial endometrioid adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6760
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000233",
          "MEDGEN:234467",
          "NCIT:C6287",
          "ONCOTREE:UEC",
          "UMLS:C1336905",
          "icd11.foundation:671511103"
        ],
        "synonyms": [
          "endometrial endometrioid adenocarcinoma",
          "endometrioid adenocarcinoma of endometrium",
          "endometrioid adenocarcinoma of the endometrium",
          "endometrioid carcinoma of endometrium",
          "endometrioid carcinoma of the endometrium",
          "endometrioid endomet. adenocar.",
          "endometrioid endometrial adenocarcinoma",
          "uterine corpus endometrioid adenocarcinoma",
          "uterine corpus endometrioid carcinoma",
          "uterine endometrioid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary endometrial adenocarcinoma composed of neoplastic cells that form complex glandular patterns associated with budding and branching of the neoplastic glands. The neoplastic glands resemble those of the normal endometrium and may or may not be associated with sheet-like proliferation of malignant cells. Endometrioid adenocarcinoma is the most commonly seen morphologic variant of endometrial adenocarcinoma."
      },
      "child_count": 5,
      "reference_id": "MONDO:0006192"
    },
    {
      "id": 7864,
      "label": "ovarian endometrioid adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4787,
        5685,
        6760,
        7120
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5828",
          "EFO:1000416",
          "GARD:0021893",
          "MEDGEN:91087",
          "NCIT:C7979",
          "ONCOTREE:EOV",
          "Orphanet:454723",
          "SCTID:254852002",
          "UMLS:C0346163"
        ],
        "synonyms": [
          "endometrioid adenocarcinoma of ovary",
          "endometrioid adenocarcinoma of the ovary",
          "endometrioid cancer of ovary",
          "endometrioid cancer of the ovary",
          "endometrioid carcinoma of ovary",
          "endometrioid carcinoma of the ovary",
          "endometrioid ovary carcinoma",
          "endometrium adenocarcinoma of ovary",
          "ovarian endometrioid adenocarcinoma",
          "ovarian endometrioid cancer",
          "ovarian endometrioid carcinoma",
          "ovary endometrium adenocarcinoma",
          "endometrioid ovarian cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An endometrioid adenocarcinoma arising from the ovary. It comprises 10% to 25% of all primary ovarian carcinomas. Grossly, endometrioid carcinoma may present as a cystic or solid mass. Microscopically, the tumor greatly resembles the appearance of the ordinary type of endometrial adenocarcinoma. As a group, endometrioid carcinoma has a prognosis twice as good as that of serous or mucinous carcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006335"
    }
  ],
  "roots": [
    {
      "id": 3637,
      "label": "female reproductive organ cancer"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma"
    }
  ]
}