{
  "id": 6763,
  "label": "essential thrombocythemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005029",
  "properties": {
    "xrefs": [
      "DOID:2224",
      "EFO:0000479",
      "GARD:0006594",
      "ICD10CM:D47.3",
      "ICD9:238.71",
      "ICDO:9962/3",
      "MEDGEN:11797",
      "MESH:D013920",
      "MedDRA:10015493",
      "NANDO:2100194",
      "NANDO:2200655",
      "NCIT:C3407",
      "NORD:1110",
      "ONCOTREE:ET",
      "Orphanet:3318",
      "SCTID:109994006",
      "UMLS:C0040028"
    ],
    "synonyms": [
      "ET",
      "essential thrombocytemia",
      "essential thrombocythemia",
      "essential thrombocytosis",
      "primary thrombocythemia",
      "primary thrombocytosis",
      "idiopathic thrombocythemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A chronic myeloproliferative neoplasm that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage. (WHO, 2008)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4365,
      "label": "thrombocytosis disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2228",
          "ICD9:289.9",
          "MEDGEN:163397",
          "MESH:D013922",
          "NCIT:C35530",
          "SCTID:6631009",
          "UMLS:C0836924"
        ],
        "synonyms": [
          "Platelet count increased",
          "elevated Platelet count",
          "thrombocytosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disease characterized by higher than normal platelet counts in the peripheral blood."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002249"
    },
    {
      "id": 19727,
      "label": "myeloproliferative neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6892,
        16513,
        20376
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2226",
          "EFO:0002428",
          "GARD:0009319",
          "ICD9:238.79",
          "ICDO:9960/3",
          "ICDO:9975/1",
          "MEDGEN:220955",
          "MedDRA:10028576",
          "NCIT:C4345",
          "ONCOTREE:MPN",
          "Orphanet:98274",
          "SCTID:425333006",
          "UMLS:C1292778"
        ],
        "synonyms": [
          "CMPD",
          "MPD",
          "MPN",
          "chronic myeloproliferative disease",
          "chronic myeloproliferative disorder",
          "chronic myeloproliferative neoplasm",
          "myeloproliferative disorder",
          "myeloproliferative neoplasm",
          "myeloproliferative neoplasm, chronic",
          "myeloproliferative tumor",
          "myeloproliferative tumour",
          "CMPD, U",
          "chronic myeloproliferative disorders",
          "myeloproliferative neoplasms"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)"
      },
      "child_count": 39,
      "reference_id": "MONDO:0020076"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4365,
      "label": "thrombocytosis disease"
    },
    {
      "id": 19727,
      "label": "myeloproliferative neoplasm"
    }
  ]
}