{
  "id": 6766,
  "label": "follicular thyroid adenoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005032",
  "properties": {
    "xrefs": [
      "DOID:2891",
      "DOID:6204",
      "EFO:0000499",
      "GARD:0024143",
      "HP:0000854",
      "ICDO:8330/0",
      "NCIT:C3502",
      "SCTID:255033000",
      "SCTID:255034006"
    ],
    "synonyms": [
      "adenoma of the thyroid",
      "adenoma of the thyroid gland",
      "adenoma of thyroid",
      "adenoma of thyroid gland",
      "adenoma, follicular cell, benign",
      "follicular adenoma",
      "follicular adenoma (morphologic abnormality)",
      "follicular adenoma of the thyroid",
      "follicular adenoma of the thyroid gland",
      "follicular adenoma of thyroid",
      "follicular adenoma of thyroid gland",
      "follicular thyroid adenoma",
      "thyroid adenoma",
      "thyroid adenoma (disease)",
      "thyroid follicle adenoma",
      "thyroid follicular adenoma",
      "thyroid gland adenoma",
      "thyroid gland follicular adenoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A benign, encapsulated tumor, arising from the follicular cells of the thyroid gland. It may be associated with thyroid hormone secretion but it does not have malignant characteristics."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6714,
      "label": "adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:657",
          "EFO:0000232",
          "ICDO:8140/0",
          "MEDGEN:125",
          "MESH:D000236",
          "NCIT:C2855",
          "SCTID:443416007",
          "UMLS:C0001430"
        ],
        "synonyms": [
          "adenoma",
          "acinar cell adenoma",
          "acinar cell adenoma (morphologic abnormality)",
          "adenoma, benign"
        ],
        "definition": "A neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated but non-invasive. The neoplastic epithelial cells may or may not display cellular atypia or dysplasia. In the gastrointestinal tract, when dysplasia becomes severe it is sometimes called carcinoma in situ. Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract."
      },
      "child_count": 31,
      "reference_id": "MONDO:0004972"
    },
    {
      "id": 7678,
      "label": "benign thyroid gland neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3032,
        16048
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000122",
          "GARD:0024295",
          "ICD10CM:D34",
          "ICD9:226",
          "MEDGEN:102306",
          "NCIT:C3628",
          "SCTID:92439006",
          "UMLS:C0154038"
        ],
        "synonyms": [
          "benign neoplasm of the thyroid",
          "benign neoplasm of the thyroid gland",
          "benign neoplasm of thyroid",
          "benign neoplasm of thyroid gland",
          "benign neoplasm of thyroid glands",
          "benign thyroid gland neoplasm",
          "benign thyroid gland tumor",
          "benign thyroid gland tumour",
          "benign thyroid neoplasm",
          "benign thyroid tumor",
          "benign thyroid tumour",
          "benign tumor of the thyroid",
          "benign tumor of the thyroid gland",
          "benign tumor of thyroid",
          "benign tumor of thyroid gland",
          "benign tumour of the thyroid",
          "benign tumour of the thyroid gland",
          "benign tumour of thyroid",
          "benign tumour of thyroid gland",
          "thyroid gland benign neoplasm",
          "thyroid neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm arising from the thyroid gland."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006107"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8010/0",
          "ICDO:8011/0",
          "MEDGEN:90747",
          "NCIT:C4092",
          "UMLS:C0334232"
        ],
        "synonyms": [
          "benign epithelial neoplasm",
          "benign epithelial tumor",
          "benign epithelial tumour",
          "benign epithelioma",
          "benign neoplasm of epithelium",
          "benign neoplasm of the epithelium",
          "benign tumor of epithelium",
          "benign tumor of the epithelium",
          "benign tumour of epithelium",
          "benign tumour of the epithelium",
          "epithelial neoplasm, benign",
          "epithelioma, benign"
        ],
        "definition": "A neoplasm arising from the epithelial cells. It is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign epithelial neoplasms remain confined to the original site of growth and only rarely metastasize to other anatomic sites."
      },
      "child_count": 50,
      "reference_id": "MONDO:0036976"
    }
  ],
  "children": [
    {
      "id": 6266,
      "label": "thyroid gland fetal adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6766
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8102",
          "GARD:0024018",
          "ICDO:8333/0",
          "MEDGEN:137743",
          "NCIT:C4160",
          "UMLS:C0334328"
        ],
        "synonyms": [
          "microfollicular adenoma",
          "microfollicular adenoma (morphologic abnormality)",
          "thyroid fetal adenoma",
          "thyroid foetal adenoma",
          "thyroid gland microfollicular adenoma",
          "foetal adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A thyroid gland adenoma composed of microfollicular structures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004460"
    },
    {
      "id": 6286,
      "label": "thyroid gland oncocytic adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5352,
        6766
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8162",
          "GARD:0024029",
          "MEDGEN:237009",
          "NCIT:C6042",
          "ONCOTREE:OAT",
          "UMLS:C1336750"
        ],
        "synonyms": [
          "OAT",
          "benign oncocytoma of the thyroid",
          "thyroid gland oncocytic adenoma",
          "Hurthle cell adenoma",
          "Hurthle cell adenoma of the thyroid",
          "Hurthle cell adenoma of the thyroid gland",
          "Hurthle cell adenoma of thyroid",
          "Hurthle cell adenoma of thyroid gland",
          "benign oncocytoma of the thyroid gland",
          "benign oncocytoma of thyroid",
          "benign oncocytoma of thyroid gland",
          "benign thyroid gland oncocytoma",
          "benign thyroid oncocytoma",
          "follicular adenoma of the thyroid gland of the oxyphilic cell type",
          "follicular adenoma of the thyroid of the oxyphilic cell type",
          "follicular adenoma of thyroid gland of oxyphilic cell type",
          "follicular adenoma of thyroid of oxyphilic cell type",
          "oncocytic adenoma of the thyroid",
          "oncocytic adenoma of the thyroid gland",
          "oncocytic adenoma of thyroid",
          "oncocytic adenoma of thyroid gland",
          "thyroid Hurthle cell adenoma",
          "thyroid follicular adenoma of oxyphilic cell type",
          "thyroid follicular adenoma of the oxyphilic cell type",
          "thyroid gland Hurthle cell adenoma",
          "thyroid gland follicular adenoma of oxyphilic cell type",
          "thyroid gland follicular adenoma of the oxyphilic cell type",
          "thyroid oncocytic adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A thyroid gland adenoma composed of large cells with abundant granular eosinophilic cytoplasm and large nuclei with prominent nucleoli."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004483"
    },
    {
      "id": 6325,
      "label": "thyroid gland atypical follicular adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6766
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8292",
          "GARD:0024049",
          "ICDO:8330/1",
          "MEDGEN:224756",
          "NCIT:C27729",
          "UMLS:C1266046"
        ],
        "synonyms": [
          "atypical follicular adenoma",
          "atypical follicular adenoma (morphologic abnormality)",
          "thyroid gland atypical follicular adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A thyroid gland adenoma with increased cellularity and nuclear atypia. There is no capsular or vascular invasion. The clinical course is benign."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004524"
    },
    {
      "id": 6356,
      "label": "thyroid gland macrofollicular adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6766
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8419",
          "GARD:0024068",
          "ICDO:8334/0",
          "MEDGEN:90763",
          "NCIT:C4161",
          "UMLS:C0334329"
        ],
        "synonyms": [
          "macrofollicular adenoma",
          "macrofollicular adenoma (morphologic abnormality)",
          "colloid adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A thyroid gland adenoma composed of large size follicles."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004558"
    },
    {
      "id": 29360,
      "label": "toxic thyroid adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6766,
        29358
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:549890",
          "UMLS:C0302840"
        ],
        "synonyms": [
          "toxic adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A condition in which a single benign adenoma on the thyroid gland  autonomously secretes excessive thyroid hormone, leading to primary hyperthyroidism."
      },
      "child_count": 0,
      "reference_id": "MONDO:1060202"
    }
  ],
  "roots": [
    {
      "id": 6714,
      "label": "adenoma"
    },
    {
      "id": 7678,
      "label": "benign thyroid gland neoplasm"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm"
    }
  ]
}