{
  "id": 6777,
  "label": "hypertrophic cardiomyopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005045",
  "properties": {
    "xrefs": [
      "DOID:11984",
      "EFO:0000538",
      "HP:0001639",
      "ICD10CM:I42.1",
      "ICD10CM:I42.2",
      "ICD9:425.1",
      "ICD9:425.11",
      "ICD9:425.4",
      "MEDGEN:2881",
      "MESH:D002312",
      "MedDRA:10020871",
      "NANDO:1200286",
      "NANDO:1200288",
      "NANDO:2100054",
      "NANDO:2200229",
      "NANDO:2201042",
      "NCIT:C34449",
      "Orphanet:217569",
      "SCTID:233873004",
      "UMLS:C0007194",
      "icd11.foundation:1830681485"
    ],
    "synonyms": [
      "hypertrophic cardiomyopathy",
      "hypertrophic subaortic stenosis",
      "obstructive hypertrophic cardiomyopathy",
      "familial hypertrophic cardiomyopathy",
      "HCM - hypertrophic cardiomyopathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 3007,
      "label": "intrinsic cardiomyopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6735
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060036",
          "GARD:0022809"
        ],
        "synonyms": [
          "intrinsic cardiomyopathy",
          "primary cardiomyopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A cardiomyopathy that is due to abnormalities in heart muscle cells."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000591"
    }
  ],
  "children": [
    {
      "id": 16875,
      "label": "non-familial hypertrophic cardiomyopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6777
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1843178",
          "Orphanet:217598",
          "UMLS:C5680883"
        ],
        "synonyms": [
          "acquired hypertrophic cardiomyopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An instance of hypertrophic cardiomyopathy that is acquired during the lifetime of the individual."
      },
      "child_count": 3,
      "reference_id": "MONDO:0016330"
    },
    {
      "id": 16940,
      "label": "progressive sensorineural hearing loss-hypertrophic cardiomyopathy syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6777
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017145",
          "MEDGEN:930500",
          "Orphanet:228012",
          "UMLS:C4304831"
        ],
        "synonyms": [
          "progressive neurosensory deafness-hypertrophic cardiomyopathy syndrome",
          "progressive neurosensory hearing loss-hypertrophic cardiomyopathy syndrome",
          "progressive sensorineural deafness-hypertrophic cardiomyopathy syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Progressive sensorineural hearing loss - hypertrophic cardiomyopathy is an extremely rare disorder described in one family to date that is characterized by progressive, late onset, autosomal dominant sensorineural hearing loss, QT interval prolongation, and mild cardiac hypertrophy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016424"
    },
    {
      "id": 21518,
      "label": "familial hypertrophic cardiomyopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6777,
        6933
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080326",
          "MEDGEN:183649",
          "MESH:D024741",
          "NCIT:C84773",
          "OMIMPS:192600",
          "Orphanet:155",
          "SCTID:471885006",
          "UMLS:C0949658",
          "icd11.foundation:1408928442"
        ],
        "synonyms": [
          "cardiomyopathy, familial hypertrophic",
          "familial hypertrophic cardiomyopathy",
          "familila or idiopathic hypertrophic obstructive cardiomyopathy",
          "hereditary hypertrophic cardiomyopathy",
          "hypertrophic familial cardiomyopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Hypertrophic cardiomyopathy caused by mutations in the genes encoding components of the sarcomere, in the absence of predisposing conditions."
      },
      "child_count": 80,
      "reference_id": "MONDO:0024573"
    }
  ],
  "roots": [
    {
      "id": 3007,
      "label": "intrinsic cardiomyopathy"
    }
  ]
}