{
  "id": 6781,
  "label": "invasive ductal and lobular carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005050",
  "properties": {
    "xrefs": [
      "EFO:0000552",
      "ICDO:8522/3",
      "MEDGEN:235231",
      "NCIT:C7688",
      "UMLS:C1334277"
    ],
    "synonyms": [
      "infiltrating ductal and lobular carcinoma",
      "invasive duct and lobular carcinoma",
      "invasive ductal and lobular carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "An invasive ductal breast carcinoma associated with a lobular carcinomatous component. The lobular carcinomatous component may be in situ or invasive."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6698,
      "label": "invasive ductal breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7234,
        7803
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3008",
          "EFO:0000186",
          "ICD9:174.8",
          "ICDO:8500/3",
          "ICDO:8521/3",
          "MEDGEN:730612",
          "NCIT:C4194",
          "ONCOTREE:IDC",
          "SCTID:408643008",
          "UMLS:C1412014"
        ],
        "synonyms": [
          "infiltrating ductal adenocarcinoma",
          "infiltrating ductal breast carcinoma",
          "infiltrating ductal carcinoma",
          "infiltrating ductal carcinoma of breast",
          "infiltrating ductal carcinoma of the breast",
          "invasive ductal adenocarcinoma",
          "invasive ductal breast carcinoma",
          "invasive ductal carcinoma",
          "invasive ductal carcinoma of breast",
          "invasive ductal carcinoma of the breast",
          "invasive ductal carcinoma, NST",
          "invasive ductal carcinoma, No specific type",
          "breast invasive ductal carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "The most common type of invasive breast carcinoma, accounting for approximately 70% of breast carcinomas. The gross appearance is usually typical with an irregular stellate outline. Microscopically, randomly arranged epithelial elements are seen. When large sheets of malignant cells are present, necrosis may be seen. With adequate tissue sampling, in situ carcinoma can be demonstrated in association with the infiltrating carcinoma. The in situ component is nearly always ductal but occasionally may be lobular or both."
      },
      "child_count": 20,
      "reference_id": "MONDO:0004953"
    },
    {
      "id": 7844,
      "label": "mixed lobular and ductal breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6729,
        7464
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000382",
          "ICD9:174.8",
          "MEDGEN:1779609",
          "NCIT:C5160",
          "ONCOTREE:MDLC",
          "SCTID:444604002",
          "UMLS:C5441546"
        ],
        "synonyms": [
          "ductal and lobular carcinoma",
          "mixed ductal and lobular breast carcinoma",
          "mixed ductal and lobular carcinoma of breast",
          "mixed ductal and lobular carcinoma of the breast",
          "mixed lobular and ductal breast carcinoma",
          "mixed lobular and ductal carcinoma",
          "mixed lobular and ductal carcinoma of breast",
          "mixed lobular and ductal carcinoma of the breast",
          "breast mixed ductal and lobular carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A breast carcinoma characterized by the presence of a lobular and a ductal component. The ductal component comprises less than 50 percent of the tumor."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006306"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6698,
      "label": "invasive ductal breast carcinoma"
    },
    {
      "id": 7844,
      "label": "mixed lobular and ductal breast carcinoma"
    }
  ]
}