{
  "id": 6782,
  "label": "invasive lobular breast carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005051",
  "properties": {
    "xrefs": [
      "DOID:3457",
      "EFO:0000553",
      "MEDGEN:75994",
      "NCIT:C7950",
      "ONCOTREE:ILC",
      "UMLS:C0279565"
    ],
    "synonyms": [
      "lobular carcinoma",
      "lobular carcinoma (morphologic abnormality)",
      "lobular carcinoma NOS (morphologic abnormality)",
      "lobular carcinoma of the breast",
      "classic invasive lobular carcinoma",
      "infiltrating lobular adenocarcinoma",
      "infiltrating lobular breast carcinoma",
      "infiltrating lobular carcinoma of breast",
      "infiltrating lobular carcinoma of the breast",
      "invasive lobular adenocarcinoma",
      "invasive lobular breast carcinoma",
      "invasive lobular carcinoma",
      "invasive lobular carcinoma of breast",
      "invasive lobular carcinoma of the breast",
      "invasive lobular carcinoma, classic type",
      "breast invasive lobular carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "An infiltrating lobular adenocarcinoma of the breast. The malignant cells lack cohesion and are arranged individually or in a linear manner (Indian files), or as narrow trabeculae within the stroma. The malignant cells are usually smaller than those of ductal carcinoma, are less pleomorphic, and have fewer mitotic figures."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2991,
      "label": "breast lobular carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6729
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050938",
          "EFO:0008509",
          "ICDO:8520/3",
          "MEDGEN:64634",
          "NCIT:C3771",
          "SCTID:278054005",
          "UMLS:C0206692"
        ],
        "synonyms": [
          "carcinoma of lobule of mammary gland",
          "lobular adenocarcinoma",
          "lobular breast carcinoma",
          "lobular carcinoma",
          "lobular carcinoma of breast",
          "lobular carcinoma of the breast",
          "lobule of mammary gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An adenocarcinoma of the breast arising from the lobules. This is a relatively uncommon carcinoma, represents approximately 10% of the breast adenocarcinomas and is often bilateral or multifocal."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000552"
    },
    {
      "id": 7803,
      "label": "invasive breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6730,
        23004
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000307",
          "MEDGEN:163435",
          "NCIT:C9245",
          "ONCOTREE:BRCA",
          "SCTID:713609000",
          "UMLS:C0853879",
          "icd11.foundation:2090549892"
        ],
        "synonyms": [
          "infiltrating breast cancer",
          "infiltrating breast carcinoma",
          "infiltrating carcinoma of breast",
          "infiltrating carcinoma of the breast",
          "invasive breast cancer",
          "invasive breast carcinoma",
          "invasive carcinoma of breast",
          "invasive carcinoma of the breast",
          "invasive mammary carcinoma",
          "BRCA"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A carcinoma that infiltrates the breast parenchyma. The vast majority are adenocarcinomas arising from the terminal ductal lobular unit (TDLU). Often, the invasive adenocarcinoma co-exists with ductal or lobular carcinoma in situ. It is the most common carcinoma affecting women."
      },
      "child_count": 22,
      "reference_id": "MONDO:0006256"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2991,
      "label": "breast lobular carcinoma"
    },
    {
      "id": 7803,
      "label": "invasive breast carcinoma"
    }
  ]
}