{
  "id": 6784,
  "label": "ischemic disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005053",
  "properties": {
    "xrefs": [
      "DOID:326",
      "MEDGEN:5899",
      "MESH:D007511",
      "NCIT:C34738",
      "SCTID:52674009",
      "UMLS:C0022116"
    ],
    "synonyms": [
      "ischemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Lack of blood supply to an area of the body, resulting in impairment of tissue oxygenation."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 7065,
      "label": "vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:178",
          "EFO:0004264",
          "ICD10CM:I00-I99",
          "ICD10CM:I70-I79",
          "ICD9:442.9",
          "MEDGEN:22621",
          "MESH:D014652",
          "NANDO:2100294",
          "NCIT:C35117",
          "SCTID:27550009",
          "UMLS:C0042373"
        ],
        "synonyms": [
          "disease of vasculature",
          "disease or disorder of vasculature",
          "disorder of vasculature",
          "vascular disorder",
          "vasculature disease",
          "vasculature disease or disorder",
          "vasculopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005385"
    }
  ],
  "children": [
    {
      "id": 2949,
      "label": "limb ischemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6784
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050852",
          "MEDGEN:754513",
          "SCTID:21631000119105",
          "UMLS:C2945695"
        ],
        "synonyms": [
          "ischaemic disease of limb",
          "ischemic disease of limb",
          "limb ischaemic disease",
          "limb ischemia",
          "limb ischemic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A ischemia that involves the limb."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000491"
    },
    {
      "id": 3745,
      "label": "retinal ischemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6784,
        6979,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12510",
          "ICD10CM:H35.82",
          "ICD9:362.84",
          "MEDGEN:102372",
          "SCTID:26468004",
          "UMLS:C0162291"
        ],
        "synonyms": [
          "ischaemic disease of retina",
          "ischemic disease of retina",
          "retina ischaemic disease",
          "retina ischemic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A ischemic disease that involves the retina."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001538"
    },
    {
      "id": 6993,
      "label": "brain ischemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6784,
        12183
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2316",
          "ICD9:348.89",
          "MEDGEN:182975",
          "MESH:D002545",
          "NCIT:C78394",
          "SCTID:389100007",
          "UMLS:C0917798"
        ],
        "synonyms": [
          "brain ischaemic disease",
          "brain ischemia",
          "brain ischemic disease",
          "cerebrovascular ischemia",
          "ischaemic disease of brain",
          "ischemia cerebrovascular",
          "ischemic disease of brain"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Diminished or absent blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurologic damage."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005299"
    },
    {
      "id": 20085,
      "label": "ischemic bowel disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6756,
        6784
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:412148",
          "NCIT:C35212",
          "UMLS:C2004435"
        ],
        "synonyms": [
          "ischaemic bowel disease",
          "ischemic bowel disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Disease of the large or small intestine that is caused by inadequate blood supply."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020675"
    },
    {
      "id": 21553,
      "label": "myocardial ischemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6784,
        21552
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001375",
          "ICD10CM:I20-I25",
          "MEDGEN:101801",
          "MESH:D017202",
          "NANDO:2100070",
          "NCIT:C50625",
          "SCTID:414545008",
          "UMLS:C0151744",
          "icd11.foundation:1964269418"
        ],
        "synonyms": [
          "IHD",
          "ischaemic disease of myocardium",
          "ischaemic heart disease",
          "ischemic disease of myocardium",
          "ischemic heart disease",
          "myocardium ischaemic disease",
          "myocardium ischemic disease",
          "disease, ischaemic heart",
          "disease, ischemic heart",
          "diseases, ischaemic heart",
          "diseases, ischemic heart",
          "heart disease, ischaemic",
          "heart disease, ischemic",
          "heart diseases, ischaemic",
          "heart diseases, ischemic",
          "ischaemic heart diseases",
          "ischemia, myocardial",
          "ischemias, myocardial",
          "ischemic heart diseases",
          "myocardial Ischemias"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (coronary artery disease), to obstruction by a thrombus (coronary thrombosis), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (myocardial infarction)."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024644"
    },
    {
      "id": 23024,
      "label": "peripheral ischemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6784,
        7066
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:115991",
          "SCTID:233958001",
          "UMLS:C0235490"
        ],
        "synonyms": [
          "peripheral ischemia",
          "peripheral ischaemic vascular disease",
          "peripheral ischemic vascular disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Deficient blood distribution to the limbs caused by narrowing or obstruction of the lumen of the peripheral arteries."
      },
      "child_count": 0,
      "reference_id": "MONDO:0041114"
    }
  ],
  "roots": [
    {
      "id": 7065,
      "label": "vascular disorder"
    }
  ]
}