{
  "id": 6785,
  "label": "Kaposi's sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005055",
  "properties": {
    "xrefs": [
      "DOID:8632",
      "EFO:0000558",
      "GARD:0006814",
      "HP:0100726",
      "ICD10CM:C46",
      "ICD9:176",
      "ICD9:176.8",
      "ICD9:176.9",
      "ICDO:9140/3",
      "MEDGEN:11321",
      "MESH:D012514",
      "MedDRA:10023284",
      "NCIT:C9087",
      "Orphanet:33276",
      "SCTID:109385007",
      "UMLS:C0036220"
    ],
    "synonyms": [
      "KS",
      "Kaposi sarcoma",
      "Kaposi's sarcoma",
      "Kaposi's sarcoma (disease)",
      "Kaposi's sarcoma of anus",
      "Kaposi's sarcoma of central nervous system",
      "Kaposi's sarcoma of esophagus",
      "Kaposi's sarcoma of gastrointestinal sites",
      "Kaposi's sarcoma of heart",
      "Kaposi's sarcoma of lymph nodes",
      "Kaposi's sarcoma of oesophagus",
      "Kaposi's sarcoma of penis",
      "Kaposi's sarcoma of skin",
      "Kaposi's sarcoma of the CNS",
      "Kaposi's sarcoma of the gallbladder",
      "Kaposi's sarcoma of the prostate",
      "Kaposi's sarcoma, lung",
      "Kaposi's sarcoma, skin",
      "anal Kaposi's sarcoma",
      "cardiac Kaposi's sarcoma",
      "central nervous system Kaposi's sarcoma",
      "conjunctival Kaposi's sarcoma",
      "corneal Kaposi's sarcoma",
      "cutaneous Kaposi's sarcoma",
      "esophageal Kaposi's sarcoma",
      "gallbladder Kaposi's sarcoma",
      "gastric Kaposi's sarcoma",
      "intestinal Kaposi's sarcoma",
      "lymph node Kaposi's sarcoma",
      "lymphadenopathic Kaposi's sarcoma",
      "multiple hemorrhagic sarcoma",
      "palate Kaposi's sarcoma",
      "penis Kaposi's sarcoma",
      "prostate Kaposi's sarcoma",
      "pulmonary Kaposi's sarcoma",
      "soft tissue Kaposi's sarcoma",
      "HHV8",
      "KSHV",
      "Kaposi sarcoma herpesvirus",
      "Mediterranean Kaposi sarcoma",
      "human herpesvirus 8",
      "non AIDS related Kaposi sarcoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A malignant neoplasm characterized by a vascular proliferation which usually contains blunt endothelial cells. Erythrocyte extravasation and hemosiderin deposition are frequently present. The most frequent site of involvement is the skin; however it may also occur internally. It generally develops in people with compromised immune systems including those with acquired immune deficiency syndrome (AIDS)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6834,
      "label": "viral infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:934",
          "EFO:0000763",
          "ICD9:060-066",
          "ICD9:066.9",
          "ICD9:078.89",
          "ICD9:079.99",
          "MESH:D014777",
          "NCIT:C3439",
          "SCTID:34014006"
        ],
        "synonyms": [
          "Viruses caused disease or disorder",
          "Viruses disease or disorder",
          "Viruses infection",
          "Viruses infectious disease",
          "infection, viral",
          "viral disease",
          "viral disorder",
          "viral infection",
          "infections, Viruses"
        ],
        "definition": "Any disease caused by a virus."
      },
      "child_count": 42,
      "reference_id": "MONDO:0005108"
    },
    {
      "id": 16085,
      "label": "human herpesvirus 8-related tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17658
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019830",
          "MEDGEN:1843228",
          "NCIT:C27697",
          "Orphanet:102024",
          "UMLS:C5680371"
        ],
        "synonyms": [
          "HHV-8-related disorder"
        ]
      },
      "child_count": 3,
      "reference_id": "MONDO:0015157"
    },
    {
      "id": 17394,
      "label": "angiosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0001816",
          "EFO:0003968",
          "GARD:0020900",
          "HP:0200058",
          "ICD9:171.9",
          "ICDO:9120/3",
          "MEDGEN:42385",
          "MESH:D006394",
          "MedDRA:10002476",
          "NCIT:C3088",
          "ONCOTREE:ANGS",
          "Orphanet:263413",
          "SCTID:403977003",
          "UMLS:C0018923"
        ],
        "synonyms": [
          "angiosarcoma",
          "angiosarcoma (disease)",
          "blood vessel sarcoma",
          "hemangiosarcoma",
          "hemangiosarcoma, malignant",
          "malignant angioendothelioma",
          "malignant hemangioendothelioma",
          "sarcoma of blood vessel",
          "vascular sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma."
      },
      "child_count": 38,
      "reference_id": "MONDO:0016982"
    }
  ],
  "children": [
    {
      "id": 6909,
      "label": "iatrogenic Kaposi's sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6785,
        23227
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024161",
          "MEDGEN:235203",
          "NCIT:C35873",
          "UMLS:C1334149"
        ],
        "synonyms": [
          "iatrogenic Kaposi sarcoma",
          "iatrogenic Kaposi's sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A Kaposi sarcoma that develops after organ transplantation or immunosuppressive treatment."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005188"
    },
    {
      "id": 20979,
      "label": "classic Kaposi sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6785
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025368",
          "MEDGEN:78931",
          "NCIT:C9112",
          "UMLS:C0279084",
          "icd11.foundation:1595913346"
        ],
        "synonyms": [
          "Kaposi sarcoma classical type",
          "Kaposi sarcoma, classic",
          "Kaposi's sarcoma, classical type",
          "classic Kaposi sarcoma",
          "classic Kaposi's sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A vascular sarcoma that commonly occurs in the lower extremities. It occurs predominantly in elderly male patients of southern European ancestry. It is characterized by the presence of purple, red-blue, or dark brown macular lesions, plaques and nodules. This disease is usually slow growing, although it can spread to the lungs and the gastrointestinal tract. If necessary, cutaneous lesions can be treated with radiation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022772"
    },
    {
      "id": 21120,
      "label": "endemic Kaposi sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6785
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010431",
          "MEDGEN:698516",
          "UMLS:C1275231",
          "icd11.foundation:509381237"
        ],
        "synonyms": [
          "African Kaposi sarcoma",
          "African/endemic Kaposi sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0023067"
    },
    {
      "id": 21566,
      "label": "colorectal Kaposi sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6785,
        7430,
        21545,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025451",
          "MEDGEN:474466",
          "NCIT:C96510",
          "UMLS:C3272833"
        ],
        "synonyms": [
          "Kaposi's sarcoma (disease) of large intestine",
          "colorectal Kaposi sarcoma",
          "large intestinal Kaposi sarcoma",
          "large intestine Kaposi's sarcoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A Kaposi sarcoma that arises from the colon or rectum."
      },
      "child_count": 8,
      "reference_id": "MONDO:0024659"
    }
  ],
  "roots": [
    {
      "id": 6834,
      "label": "viral infectious disease"
    },
    {
      "id": 16085,
      "label": "human herpesvirus 8-related tumor"
    },
    {
      "id": 17394,
      "label": "angiosarcoma"
    }
  ]
}