{
  "id": 6792,
  "label": "lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005062",
  "properties": {
    "xrefs": [
      "DOID:0060058",
      "EFO:0000574",
      "ICD9:200.0",
      "ICD9:200.1",
      "ICD9:202.80",
      "ICDO:9590/3",
      "MEDGEN:44223",
      "MESH:D008223",
      "MedDRA:10025310",
      "NANDO:2100004",
      "NCIT:C3208",
      "ONCOTREE:MLYM",
      "Orphanet:223735",
      "SCTID:118600007",
      "UMLS:C0024299"
    ],
    "synonyms": [
      "lymphoma",
      "lymphoma (Hodgkin and non-Hodgkin)",
      "lymphoma (Hodgkin's and non-Hodgkin's)",
      "lymphoma, malignant",
      "lymphomatous",
      "malignant lymphoma",
      "MLYM"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 27,
  "parents": [
    {
      "id": 6881,
      "label": "lymphoid neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0001642",
          "GARD:0024157",
          "ICD9:200.7",
          "MEDGEN:108626",
          "NCIT:C7065",
          "ONCOTREE:LYMPH",
          "UMLS:C0598798"
        ],
        "synonyms": [
          "lymphocytic and plasma cell neoplasm",
          "lymphocytic and plasma cell tumor",
          "lymphocytic and plasma cell tumour",
          "lymphocytic and plasmacytic neoplasm",
          "lymphocytic neoplasm",
          "lymphocytic tumor",
          "lymphocytic tumour",
          "lymphoid and plasma cell tumor",
          "lymphoid and plasma cell tumour",
          "lymphoid and plasmacytic neoplasm",
          "lymphoid and plasmacytic tumor",
          "lymphoid and plasmacytic tumour",
          "lymphoid neoplasm",
          "lymphoid tumor",
          "lymphoid tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm composed of a lymphocytic cell population which is usually malignant (clonal) by molecular genetic and/or immunophenotypic analysis. Lymphocytic neoplasms include Hodgkin and non-Hodgkin lymphomas, acute and chronic lymphocytic leukemias, and plasma cell neoplasms."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005157"
    },
    {
      "id": 16514,
      "label": "lymphoid hemopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020131",
          "MEDGEN:1842533",
          "Orphanet:171898",
          "UMLS:C5680515"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0015757"
    }
  ],
  "children": [
    {
      "id": 3262,
      "label": "prostate lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        9621
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10290",
          "GARD:0022860",
          "MEDGEN:235500",
          "NCIT:C5533",
          "UMLS:C1335512"
        ],
        "synonyms": [
          "lymphoma of prostate",
          "lymphoma of prostate gland",
          "lymphoma of the prostate",
          "primary prostate lymphoma",
          "prostate gland lymphoma",
          "prostate lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare non-Hodgkin or Hodgkin lymphoma that arises from the prostate gland."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000996"
    },
    {
      "id": 3377,
      "label": "nasal cavity lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3375,
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10813",
          "GARD:0022889",
          "MEDGEN:233747",
          "NCIT:C6074",
          "UMLS:C1334921"
        ],
        "synonyms": [
          "lymphoma of nasal cavity",
          "lymphoma of the nasal cavity",
          "nasal cavity lymphoma",
          "primary nasal cavity lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A primary lymphoma that affects the nasal cavity and the bulk of the tumor is in this anatomic area."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001130"
    },
    {
      "id": 3603,
      "label": "bladder lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3431,
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11821",
          "GARD:0022929",
          "MEDGEN:231948",
          "NCIT:C6164",
          "UMLS:C1332561"
        ],
        "synonyms": [
          "lymphoma of bladder",
          "lymphoma of the bladder",
          "lymphoma of the urinary bladder",
          "lymphoma of urinary bladder",
          "primary bladder lymphoma",
          "urinary bladder lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that involves the urinary bladder."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001381"
    },
    {
      "id": 3638,
      "label": "tracheal lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3628,
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12001",
          "GARD:0022941",
          "MEDGEN:277825",
          "NCIT:C6248",
          "UMLS:C1336773"
        ],
        "synonyms": [
          "lymphoma of the trachea",
          "lymphoma of trachea",
          "primary tracheal lymphoma",
          "trachea lymphoma",
          "tracheal lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare lymphoma that arises from the trachea. Signs and symptoms include dyspnea, cough, wheezing, and stridor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001417"
    },
    {
      "id": 3708,
      "label": "retroperitoneal lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        7537
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12339",
          "GARD:0022957",
          "MEDGEN:233407",
          "NCIT:C7353",
          "SCTID:422853008",
          "UMLS:C1335779"
        ],
        "synonyms": [
          "lymphoma of retroperitoneal space",
          "primary retroperitoneal lymphoma",
          "retroperitoneal lymphoma",
          "retroperitoneal space lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that involves the retroperitoneal space."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001499"
    },
    {
      "id": 4138,
      "label": "ureteral lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        9910
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14489",
          "GARD:0023051",
          "MEDGEN:234458",
          "NCIT:C6175",
          "UMLS:C1336876"
        ],
        "synonyms": [
          "lymphoma of the ureter",
          "lymphoma of ureter",
          "primary ureter lymphoma",
          "ureter lymphoma",
          "ureteral lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that involves the ureter."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001977"
    },
    {
      "id": 4346,
      "label": "ovarian lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        9481
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2150",
          "GARD:0023093",
          "MEDGEN:276669",
          "NCIT:C40021",
          "UMLS:C1518720"
        ],
        "synonyms": [
          "lymphoma of ovary",
          "ovarian lymphoma",
          "ovary lymphoma",
          "primary ovarian lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that affects the ovary. Lymphomatous involvement of the ovary is rare and in approximately half of the cases both ovaries are affected."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002227"
    },
    {
      "id": 5545,
      "label": "B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5822",
          "GARD:0010897",
          "ICDO:9596/3",
          "MEDGEN:234323",
          "NCIT:C37869",
          "UMLS:C1333878"
        ],
        "synonyms": [
          "B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and Classic Hodgkin lymphoma",
          "B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma",
          "Gray zone lymphoma",
          "Grey zone lymphoma",
          "Hodgkin-like anaplastic large cell lymphoma",
          "large B-cell lymphoma with Hodgkin features"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A group of lymphomas displaying molecular, morphologic, immunophenotypic, and clinical overlap between classical Hodgkin lymphoma and diffuse large B-cell lymphoma. This term particularly applies to mediastinal lymphomas with overlapping features of mediastinal (thymic) large B-cell lymphoma and classical Hodgkin lymphoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003658"
    },
    {
      "id": 5546,
      "label": "pediatric lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        8005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5823",
          "GARD:0023606",
          "MEDGEN:232062",
          "NANDO:2100004",
          "NCIT:C5165",
          "UMLS:C1332979"
        ],
        "synonyms": [
          "lymphoma",
          "childhood lymphoma",
          "pediatric lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A Hodgkin or non-Hodgkin lymphoma that occurs during childhood."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003659"
    },
    {
      "id": 5547,
      "label": "adult lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5825",
          "GARD:0023607",
          "MEDGEN:233965",
          "NANDO:2100004",
          "NCIT:C7587",
          "UMLS:C1332206"
        ],
        "synonyms": [
          "lymphoma",
          "adult lymphoma",
          "lymphoma of adults"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that occurs in an adult."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003660"
    },
    {
      "id": 5548,
      "label": "breast lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        8659
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5826",
          "GARD:0023608",
          "MEDGEN:309939",
          "NCIT:C4671",
          "SCTID:278052009",
          "UMLS:C1704251"
        ],
        "synonyms": [
          "breast lymphoma",
          "lymphoma of breast",
          "lymphoma of the breast",
          "primary breast lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that arises from the breast. There is no history of extramammary breast lymphoma and ipsilateral axillary lymph node involvement does not exclude the diagnosis of primary breast lymphoma. Most patients present with a painless breast lump. The vast majority of cases are B-cell non-Hodgkin lymphomas. Diffuse large B-cell lymphoma, follicular lymphoma, and extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue are the most common types of primary non-Hodgkin lymphoma of the breast. Primary Hodgkin lymphoma of the breast is rare."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003661"
    },
    {
      "id": 5778,
      "label": "heart lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3568,
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6547",
          "GARD:0023733",
          "MEDGEN:232331",
          "NCIT:C5368",
          "UMLS:C1332850"
        ],
        "synonyms": [
          "Cardiac lymphoma",
          "PCL",
          "Primary heart lymphoma",
          "heart lymphoma",
          "lymphoma of heart",
          "lymphoma of the heart",
          "primary Cardiac lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An extranodal lymphoma that arises from the heart and/or the pericardium. The majority of the cases are diffuse large B-cell lymphomas. Patients may present with chest pain, heart failure, pericardial effusion, arrhythmia, or syncope."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003917"
    },
    {
      "id": 5839,
      "label": "chest wall lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        20502
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6758",
          "GARD:0023761",
          "MEDGEN:232053",
          "NCIT:C6712",
          "UMLS:C1332933"
        ],
        "synonyms": [
          "chest wall cancer",
          "chest wall lymphoma",
          "lymphoma of chest wall",
          "lymphoma of the chest wall",
          "primary chest wall lymphoma",
          "malignant tumour of chest wall"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that affects the structures of the chest wall. The majority of cases are diffuse large B-cell lymphomas."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003985"
    },
    {
      "id": 5840,
      "label": "lung lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        10167
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6760",
          "GARD:0023762",
          "MEDGEN:312385",
          "NCIT:C4794",
          "UMLS:C1704383"
        ],
        "synonyms": [
          "lung lymphoma",
          "lymphoma of lung",
          "lymphoma of the lung",
          "primary lung lymphoma",
          "pulmonary lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare non-Hodgkin or Hodgkin lymphoma that arises in and is confined to the lung at the time of diagnosis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003987"
    },
    {
      "id": 5869,
      "label": "mediastinal malignant lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        7455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6868",
          "GARD:0023781",
          "MEDGEN:235311",
          "NCIT:C6633",
          "UMLS:C1334665"
        ],
        "synonyms": [
          "lymphoma of mediastinum",
          "lymphoma of the mediastinum",
          "mediastinal lymphoma",
          "mediastinal malignant lymphoma",
          "mediastinum lymphoma",
          "primary mediastinal lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that arises from the mediastinum. Representative examples include mediastinal (thymic) large B-cell lymphoma and Hodgkin lymphoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004021"
    },
    {
      "id": 5876,
      "label": "eye lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4353,
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6903",
          "GARD:0023787",
          "MEDGEN:1788822",
          "NCIT:C35690",
          "UMLS:C0730306"
        ],
        "synonyms": [
          "eye lymphoma",
          "eyeball of camera-type eye lymphoma",
          "lymphoma of eyeball of camera-type eye",
          "primary eye lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A lymphoma that involves the eye."
      },
      "child_count": 10,
      "reference_id": "MONDO:0004034"
    },
    {
      "id": 5930,
      "label": "B-cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6569,
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:707",
          "GARD:0005877",
          "MEDGEN:86953",
          "MESH:D016393",
          "NCIT:C27907",
          "UMLS:C0079731"
        ],
        "synonyms": [
          "B-cell neoplasm",
          "B-cell lymphoma",
          "lymphoma, B-cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes."
      },
      "child_count": 10,
      "reference_id": "MONDO:0004095"
    },
    {
      "id": 6479,
      "label": "gastrointestinal lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:903",
          "GARD:0024090",
          "ICD9:202.80",
          "MEDGEN:148147",
          "NCIT:C38162",
          "SCTID:449072004",
          "UMLS:C0740372"
        ],
        "synonyms": [
          "digestive system lymphoma",
          "gastrointestinal lymphoma",
          "lymphoma of digestive system",
          "primary digestive system lymphoma",
          "primary gastrointestinal lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-Hodgkin or Hodgkin lymphoma that arises from any part of the digestive system, with the bulk of the disease localized to that site."
      },
      "child_count": 20,
      "reference_id": "MONDO:0004699"
    },
    {
      "id": 6697,
      "label": "Hodgkins lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        17660
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8567",
          "EFO:0000183",
          "GARD:0002714",
          "ICD10CM:C81",
          "ICD9:201",
          "ICD9:201.0",
          "ICD9:201.1",
          "ICD9:201.2",
          "ICD9:201.9",
          "ICD9:201.90",
          "ICDO:9650/3",
          "MESH:D006689",
          "NANDO:2200024",
          "NCIT:C9357",
          "NORD:1246",
          "ONCOTREE:HL",
          "Orphanet:98293",
          "icd11.foundation:1528863768"
        ],
        "synonyms": [
          "HL",
          "Hodgkin disease",
          "Hodgkin lymphoma",
          "Hodgkin's Disease",
          "Hodgkin's disease",
          "Hodgkin's lymphoma",
          "stage I subdiaphragmatic Hodgkin lymphoma",
          "stage II subdiaphragmatic Hodgkin lymphoma",
          "Hodgkin's sarcoma",
          "lymphoma, Hodgkin's"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A heterogeneous group of malignant lymphoid neoplasms of B-cell origin characterized histologically by the presence of Hodgkin and Reed-Sternberg (HRS) cells in the vast majority of cases. There are two distinct subtypes: nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Hodgkin lymphoma involves primarily lymph nodes."
      },
      "child_count": 10,
      "reference_id": "MONDO:0004952"
    },
    {
      "id": 6707,
      "label": "peripheral T-cell lymphoma, not otherwise specified",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        6891
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000211",
          "GARD:0027711",
          "NANDO:2200028",
          "NCIT:C4340",
          "ONCOTREE:PTCL",
          "icd11.foundation:855224800"
        ],
        "synonyms": [
          "peripheral T-cell lymphoma, not otherwise specified",
          "PTCL"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Aggressive nodal or extranodal mature (peripheral) T-cell lymphomas that do not belong to the better defined entities of the remainder of mature T-cell lymphomas. This category includes the following variants: lymphoepithelioid cell variant (Lennert's lymphoma), follicular variant, and T-zone variant."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004964"
    },
    {
      "id": 7339,
      "label": "composite lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5820",
          "GARD:0020109",
          "ICDO:9596/3",
          "MEDGEN:107468",
          "MESH:D058617",
          "NCIT:C38661",
          "Orphanet:168966",
          "UMLS:C0545080"
        ],
        "synonyms": [
          "composite Hodgkin and non-Hodgkin lymphoma",
          "composite lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Coexistence of Hodgkin and non-Hodgkin lymphoma in the same anatomic site."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005710"
    },
    {
      "id": 7656,
      "label": "AIDS-related primary central nervous system lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        17658
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000077",
          "GARD:0024284",
          "MEDGEN:79263",
          "NCIT:C8284",
          "UMLS:C0281241"
        ],
        "synonyms": [
          "AIDS related lymphoma of primary central nervous system",
          "AIDS related lymphoma of the primary central nervous system",
          "AIDS related primary CNS lymphoma",
          "AIDS related primary central nervous system lymphoma",
          "AIDS-related lymphoma of primary central nervous system",
          "AIDS-related lymphoma of the primary central nervous system",
          "AIDS-related primary CNS lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma (non-Hodgkin or Hodgkin) arising from the central nervous system and occurring in HIV-positive patients."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006078"
    },
    {
      "id": 17548,
      "label": "primary organ-specific lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021064",
          "MEDGEN:1826175",
          "NCIT:C7185",
          "Orphanet:279911",
          "UMLS:C5680788"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 8,
      "reference_id": "MONDO:0017207"
    },
    {
      "id": 18836,
      "label": "non-Hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060060",
          "EFO:0005952",
          "ICDO:9591/3",
          "MEDGEN:6160",
          "MESH:D008228",
          "MedDRA:10029547",
          "NCIT:C3211",
          "ONCOTREE:NHL",
          "Orphanet:547",
          "UMLS:C0024305"
        ],
        "synonyms": [
          "NHL",
          "non-Hodgkin lymphoma",
          "non-Hodgkin's lymphoma",
          "non-Hodgkin's lymphoma (NHL)",
          "non-Hodgkins lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage."
      },
      "child_count": 10,
      "reference_id": "MONDO:0018908"
    },
    {
      "id": 19297,
      "label": "extranodal nasal NK/T cell lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        17660
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080797",
          "GARD:0007041",
          "ICD10CM:C86.0",
          "ICDO:9719/3",
          "MEDGEN:140278",
          "MedDRA:10065855",
          "NANDO:2200027",
          "NCIT:C4684",
          "Orphanet:86879",
          "UMLS:C0392788",
          "icd11.foundation:684005900"
        ],
        "synonyms": [
          "Extranodal NK/T lymphoma-nasal",
          "Extranodal NK/T-cell lymphoma, nasal type",
          "NK/T-cell lymphoma",
          "NKTCL",
          "angiocentric T-cell lymphoma",
          "lethal midline granuloma",
          "nasal T/natural killer-cell lymphoma",
          "nasal type Extranodal NK/T-cell lymphoma",
          "reticulosis, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare, malignant neoplasm mainly affecting men in the fifth decade of life, that usually arises in the nose, paranasal sinuses, orbits or upper airway, and that can present with a nasal mass, nasal bleeding, nasal obstruction, palate perforation (i.e. midline perforation of the hard palate), and mid-facial and/or upper airway destructive lesions. In advanced disease stages, which are associated with a poor prognosis, NKTCL may disseminate to other organs. A few cases of NKTCL presenting primarily in the lymph nodes have also been described."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019472"
    },
    {
      "id": 19305,
      "label": "methotrexate-associated lymphoproliferative disorders",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792,
        19730
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5821",
          "GARD:0019083",
          "MEDGEN:233702",
          "NCIT:C7184",
          "Orphanet:86904",
          "UMLS:C1334749",
          "icd11.foundation:1520483526"
        ],
        "synonyms": [
          "MTX-LPD",
          "MTX-associated lymphoproliferative disorders",
          "methotrexate-associated lymphoproliferation",
          "methotrexate-associated lymphoproliferative disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Methotrexate-associated lymphoproliferative disorders are rare immunodeficiency-associated lymphoproliferative diseases characterized by lymphoid proliferation or lymphomas (large B-cell lymphoma, T-cell lymphoma, Hodgkin lymphoma, reactive lymphadenitis and a polymorphic post-transplant lymphoproliferative disorder) that develop in patients with different autoimmune diseases treated with methotrexate. Swelling is the predominant manifestation of the disease and regression after methotrexate withdrawal is observed in a significant proportion of patients."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019483"
    },
    {
      "id": 23198,
      "label": "progressive transformation of germinal centers",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010712",
          "MEDGEN:271018",
          "MESH:C548085",
          "NCIT:C38408",
          "UMLS:C1514481"
        ],
        "synonyms": [
          "progressive transformation of Germinal centers",
          "progressive transformation of Germinal centres",
          "PTGC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Progressive transformation of germinal centers is a condition in which a lymph node becomes very enlarged (lymphadenopathy). Typically, only one lymph node is affected, though PTGC can involve multiple lymph nodes. Theneck is the most common location of affected lymph nodes, but PTGC may also affect lymph nodes in the groin and armpits. adults are more frequently affected than children, but children have a higher chance of developing PTGC multiple times (recurrence). PTGC is not considered a precancerous condition, though it has been associated with Hodgkin lymphoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043346"
    }
  ],
  "roots": [
    {
      "id": 6881,
      "label": "lymphoid neoplasm"
    },
    {
      "id": 16514,
      "label": "lymphoid hemopathy"
    }
  ]
}