{
  "id": 6823,
  "label": "squamous cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005096",
  "properties": {
    "xrefs": [
      "DOID:1749",
      "EFO:0000707",
      "ICDO:8070/3",
      "MEDGEN:2874",
      "MESH:D002294",
      "NCIT:C2929",
      "SCTID:402815007",
      "UMLS:C0007137"
    ],
    "synonyms": [
      "carcinoma, squamous cell, malignant",
      "epidermoid carcinoma",
      "epidermoid cell cancer",
      "malignant epidermoid cell neoplasm",
      "malignant epidermoid cell tumor",
      "malignant epidermoid cell tumour",
      "malignant squamous cell neoplasm",
      "malignant squamous cell tumor",
      "malignant squamous cell tumour",
      "squamous carcinoma",
      "squamous cell cancer",
      "squamous cell carcinoma",
      "squamous cell carcinoma (morphologic abnormality)",
      "squamous cell carcinoma NOS (morphologic abnormality)",
      "squamous cell epithelioma"
    ],
    "definition": "A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 39,
  "parents": [
    {
      "id": 4600,
      "label": "squamous cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3168",
          "MEDGEN:60219",
          "MESH:D018307",
          "NCIT:C3792",
          "UMLS:C0206720"
        ],
        "synonyms": [
          "epidermoid cell neoplasm",
          "epidermoid cell tumor",
          "epidermoid cell tumour",
          "squamous cell neoplasm",
          "squamous cell tumor",
          "squamous cell tumor (qualifier value)",
          "squamous cell tumour",
          "squamous cell tumour (qualifier value)"
        ],
        "definition": "A neoplasm that is composed of squamous epithelial cells. Squamous cell carcinoma is a representative example."
      },
      "child_count": 7,
      "reference_id": "MONDO:0002532"
    },
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    }
  ],
  "children": [
    {
      "id": 2965,
      "label": "bone squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4505,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050896",
          "GARD:0022783"
        ],
        "synonyms": [
          "bone tissue squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A squamous cell carcinoma that involves the bone tissue."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000514"
    },
    {
      "id": 3259,
      "label": "prostate squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        6882
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10287",
          "MEDGEN:226996",
          "NCIT:C5536",
          "ONCOTREE:PRSC",
          "SCTID:399590005",
          "UMLS:C1302530"
        ],
        "synonyms": [
          "prostate gland squamous cell carcinoma",
          "prostate squamous cell carcinoma",
          "squamous cell carcinoma of prostate",
          "squamous cell carcinoma of the prostate",
          "PRSC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An invasive prostate carcinoma characterized by the presence of squamous differentiation of the malignant cellular infiltrate. There is no evidence of glandular differentiation."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000993"
    },
    {
      "id": 3640,
      "label": "trachea squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5144,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12003",
          "EFO:1000600",
          "MEDGEN:91059",
          "NCIT:C4448",
          "SCTID:254620000",
          "UMLS:C0345946",
          "icd11.foundation:1439188070"
        ],
        "synonyms": [
          "epidermoid carcinoma of the trachea",
          "epidermoid carcinoma of trachea",
          "squamous cell carcinoma of the trachea",
          "squamous cell carcinoma of trachea",
          "trachea epidermoid carcinoma",
          "trachea squamous cell carcinoma",
          "tracheal epidermoid carcinoma",
          "tracheal squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare squamous cell carcinoma that arises from the mucosal lining of the trachea. It usually grows as an intraluminal mass and later invades extraluminal structures. The majority of patients present with hemoptysis, coughing, dyspnea, or stridor."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001419"
    },
    {
      "id": 3847,
      "label": "scrotum squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4701,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13159",
          "MEDGEN:138101",
          "NCIT:C4643",
          "SCTID:276860003",
          "UMLS:C0349551"
        ],
        "synonyms": [
          "scrotal squamous cell carcinoma",
          "scrotum squamous cell carcinoma",
          "squamous cell carcinoma of the scrotum",
          "squamous cell carcinoma of scrotum"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A rare squamous cell carcinoma that arises from the scrotum. It has been associated with exposure to environmental and industrial carcinogens. The prognosis depends on the extent of lymph node involvement."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001651"
    },
    {
      "id": 4598,
      "label": "skin squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4707,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3151",
          "MEDGEN:107512",
          "NCIT:C4819",
          "ONCOTREE:CSCC",
          "SCTID:254651007",
          "UMLS:C0553723",
          "icd11.foundation:1448983042"
        ],
        "synonyms": [
          "cutaneous squamous cell carcinoma",
          "epidermoid carcinoma of skin",
          "epidermoid carcinoma of the skin",
          "epidermoid skin carcinoma",
          "skin squamous cell cancer",
          "skin squamous cell carcinoma",
          "squamous cell carcinoma - skin",
          "squamous cell carcinoma of skin",
          "squamous cell carcinoma of the skin",
          "squamous cell skin carcinoma",
          "zone of skin squamous cell carcinoma",
          "CSCC"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma arising from the squamous cells of the epidermis. Skin squamous cell carcinoma is most commonly found on sun-exposed areas. The majority of the tumors are well-differentiated."
      },
      "child_count": 18,
      "reference_id": "MONDO:0002529"
    },
    {
      "id": 4794,
      "label": "bladder squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6727,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3742",
          "EFO:1000130",
          "MEDGEN:124645",
          "NCIT:C4031",
          "ONCOTREE:BLSC",
          "SCTID:255111004",
          "UMLS:C0279681"
        ],
        "synonyms": [
          "bladder epidermoid carcinoma",
          "bladder squamous cell cancer",
          "bladder squamous cell carcinoma",
          "epidermoid carcinoma of bladder",
          "epidermoid carcinoma of the bladder",
          "epidermoid carcinoma of the urinary bladder",
          "epidermoid carcinoma of urinary bladder",
          "squamous cell carcinoma of bladder",
          "squamous cell carcinoma of the bladder",
          "squamous cell carcinoma of the urinary bladder",
          "squamous cell carcinoma of urinary bladder",
          "urinary bladder epidermoid carcinoma",
          "urinary bladder squamous cell carcinoma",
          "BLSC"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma of the bladder arising from metaplastic epithelium. It represents less than 10% of bladder carcinomas. The exception is the Middle East along the Nile Valley, where it represents the most common form of carcinoma because of the endemic nature of schistosomiasis. Bladder squamous cell carcinoma is often associated with long-standing chronic inflammation of the bladder and usually has a poor prognosis. The diagnosis of squamous cell carcinoma of the bladder should be reserved for those tumors that are predominantly keratin forming."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002760"
    },
    {
      "id": 4798,
      "label": "urethra squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        20506
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3750",
          "GARD:0027618",
          "MEDGEN:234975",
          "NCIT:C6165",
          "ONCOTREE:USCC",
          "UMLS:C1336890"
        ],
        "synonyms": [
          "epidermoid carcinoma of the urethra",
          "epidermoid carcinoma of urethra",
          "squamous cell carcinoma of the urethra",
          "squamous cell carcinoma of urethra",
          "urethra epidermoid carcinoma",
          "urethra squamous cell carcinoma",
          "urethral epidermoid carcinoma",
          "urethral squamous cell cancer",
          "urethral squamous cell carcinoma",
          "USCC"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A well differentiated, moderately differentiated, or poorly differentiated squamous cell carcinoma that arises from the male or female urethra."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002764"
    },
    {
      "id": 4983,
      "label": "papillary squamous carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        8000
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4385",
          "ICDO:8052/3",
          "MEDGEN:83115",
          "NCIT:C4102",
          "UMLS:C0334244"
        ],
        "synonyms": [
          "papillary epidermoid carcinoma",
          "papillary epidermoid cell carcinoma",
          "papillary squamous carcinoma",
          "papillary squamous cell carcinoma"
        ],
        "definition": "A well differentiated squamous cell carcinoma characterized by a papillary, exophytic growth pattern and hyperkeratosis. The most commonly affected anatomic sites are the larynx, penis, cervix, vagina, and vulva."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002979"
    },
    {
      "id": 5405,
      "label": "basaloid squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5522",
          "EFO:1001940",
          "ICDO:8083/3",
          "MEDGEN:266085",
          "NCIT:C54244",
          "UMLS:C1266005",
          "icd11.foundation:1738201981"
        ],
        "synonyms": [
          "basaloid carcinoma",
          "basaloid carcinoma (morphologic abnormality)",
          "basaloid squamous cell carcinoma",
          "basaloid squamous cell carcinoma (morphologic abnormality)"
        ],
        "definition": "A squamous cell carcinoma characterized by the presence of cells with hyperchromatic nuclei, scant amount of cytoplasm, and peripheral nuclear palisading."
      },
      "child_count": 14,
      "reference_id": "MONDO:0003486"
    },
    {
      "id": 5406,
      "label": "pseudoglandular squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5524",
          "ICDO:8075/3",
          "MEDGEN:1731648",
          "NCIT:C4106",
          "SCTID:403901001",
          "UMLS:C5400033"
        ],
        "synonyms": [
          "adenoid squamous carcinoma",
          "adenoid squamous cell carcinoma",
          "adenoid squamous cell carcinoma (morphologic abnormality)",
          "pharyngeal tonsil squamous cell carcinoma",
          "pseudoglandular epidermoid carcinoma",
          "pseudoglandular epidermoid cell carcinoma",
          "pseudoglandular squamous carcinoma",
          "pseudoglandular squamous cell carcinoma",
          "acantholytic squamous cell carcinoma",
          "adenoacanthoma",
          "adenocarcinoma with squamous metaplasia",
          "adenocarcinoma with squamous metaplasia (morphologic abnormality)"
        ],
        "definition": "A squamous cell carcinoma characterized by the formation of gland-like structures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003487"
    },
    {
      "id": 5409,
      "label": "thymus squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7956
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5530",
          "EFO:1000579",
          "GARD:0023528",
          "MEDGEN:234814",
          "NCIT:C6455",
          "UMLS:C1336082"
        ],
        "synonyms": [
          "Thymus squamous cell carcinoma",
          "epidermoid thymic carcinoma",
          "squamous cell carcinoma of Thymus",
          "squamous cell carcinoma of the Thymus",
          "thymic squamous cell carcinoma",
          "thymus squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare primary thymic carcinoma, characterized by the presence of keratinizing or non-keratinizing malignant squamous cells. Approximately 10-20% of cases occur in combination with thymoma. The prognosis depends on the tumor stage and the degree of cellular differentiation."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003493"
    },
    {
      "id": 5410,
      "label": "ovarian squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5411,
        6823,
        6864
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5531",
          "EFO:1000432",
          "GARD:0023529",
          "MEDGEN:384474",
          "NCIT:C40093",
          "UMLS:C2019443"
        ],
        "synonyms": [
          "ovarian squamous cell cancer",
          "ovarian squamous cell carcinoma",
          "ovary squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A usually high grade squamous cell carcinoma that arises from the ovary and is not associated with a germ cell tumor. The prognosis is poor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003494"
    },
    {
      "id": 5412,
      "label": "renal pelvis squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        7174
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5534",
          "MEDGEN:66769",
          "NCIT:C7732",
          "UMLS:C0238409"
        ],
        "synonyms": [
          "epidermoid carcinoma of kidney pelvis",
          "epidermoid carcinoma of renal pelvis",
          "epidermoid carcinoma of the kidney pelvis",
          "epidermoid carcinoma of the renal pelvis",
          "kidney pelvis epidermoid carcinoma",
          "kidney pelvis squamous cell carcinoma",
          "kidney renal pelvis squamous cell cancer",
          "renal pelvis epidermoid carcinoma",
          "renal pelvis squamous cell cancer",
          "renal pelvis squamous cell carcinoma",
          "squamous cell carcinoma of kidney pelvis",
          "squamous cell carcinoma of renal pelvis",
          "squamous cell carcinoma of the kidney pelvis",
          "squamous cell carcinoma of the renal pelvis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma that involves the renal pelvis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003497"
    },
    {
      "id": 5416,
      "label": "ureter squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5539",
          "MEDGEN:237032",
          "NCIT:C6154",
          "UMLS:C1336879"
        ],
        "synonyms": [
          "epidermoid carcinoma of the ureter",
          "epidermoid carcinoma of ureter",
          "squamous cell carcinoma of the ureter",
          "squamous cell carcinoma of ureter",
          "ureter epidermoid carcinoma",
          "ureter squamous cell carcinoma",
          "ureteral epidermoid carcinoma",
          "ureteral squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare squamous cell carcinoma that arises from the ureter."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003502"
    },
    {
      "id": 5417,
      "label": "fallopian tube squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        7759
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5540",
          "GARD:0023532",
          "MEDGEN:234262",
          "NCIT:C6282",
          "UMLS:C1333596"
        ],
        "synonyms": [
          "fallopian tube squamous cell cancer",
          "fallopian tube squamous cell carcinoma",
          "squamous cell carcinoma of fallopian tube",
          "squamous cell carcinoma of the fallopian tube"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A rare squamous cell carcinoma that arises from the fallopian tube."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003503"
    },
    {
      "id": 6473,
      "label": "squamous carcinoma in situ",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6433,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8070/2",
          "ICDO:8077/2",
          "MEDGEN:83116",
          "NCIT:C27093",
          "UMLS:C0334245"
        ],
        "synonyms": [
          "carcinoma, squamous cell, in situ, malignant",
          "epidermoid carcinoma in situ",
          "epidermoid cell carcinoma in situ",
          "grade 3 SIN",
          "grade 3 squamous intraepithelial neoplasia",
          "grade III SIN",
          "grade III squamous intraepithelial neoplasia",
          "intraepithelial squamous cell carcinoma",
          "squamous carcinoma in situ",
          "squamous cell carcinoma in situ",
          "squamous cell carcinoma in-situ",
          "stage 0 squamous cell carcinoma",
          "CIN III",
          "CIN III - carcinoma in situ of cervix",
          "CIN III - severe dyskaryosis",
          "carcinoma in situ of cervix",
          "carcinoma in situ of uterine cervix",
          "cervical intraepithelial neoplasia grade III with severe dysplasia",
          "cervix Ca in situ",
          "severe dysplasia of cervix",
          "severe dysplasia of the cervix uteri",
          "squamous intraepithelial neoplasia, grade III",
          "stage 0 uterine cervix carcinoma",
          "uterine cervix in situ carcinoma"
        ],
        "definition": "A malignant epithelial neoplasm confined to the squamous epithelium, without invasion of the underlying tissues."
      },
      "child_count": 6,
      "reference_id": "MONDO:0004693"
    },
    {
      "id": 6786,
      "label": "keratinizing squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5521",
          "EFO:0000559",
          "ICDO:8071/3",
          "MEDGEN:137730",
          "NCIT:C4105",
          "UMLS:C0334247"
        ],
        "synonyms": [
          "keratinizing squamous cell carcinoma",
          "squamous cell carcinoma, keratinizing (morphologic abnormality)"
        ],
        "definition": "Squamous cell carcinomas with morphologically prominent production of keratin."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005056"
    },
    {
      "id": 6824,
      "label": "squamous cell lung carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        6862
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3907",
          "EFO:0000708",
          "ICD9:162.9",
          "MEDGEN:56202",
          "NCIT:C3493",
          "ONCOTREE:LUSC",
          "SCTID:254634000",
          "UMLS:C0149782"
        ],
        "synonyms": [
          "epidermoid cell carcinoma of lung",
          "epidermoid cell carcinoma of the lung",
          "epidermoid cell lung carcinoma",
          "lung squamous cell carcinoma",
          "squamous cell carcinoma of lung",
          "squamous cell carcinoma of the lung",
          "squamous cell lung cancer",
          "squamous cell lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A carcinoma arising from squamous bronchial epithelial cells. It may be keratinizing or non-keratinizing. Keratinizing squamous cell carcinoma is characterized by the presence of keratinization, pearl formation, and/or intercellular bridges. Non-keratinizing squamous cell carcinoma is characterized by the absence of keratinization, pearl formation, and intercellular bridges. Cigarette smoking and arsenic exposure are strongly associated with squamous cell lung carcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005097"
    },
    {
      "id": 7225,
      "label": "esophageal squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        18977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3748",
          "EFO:0005922",
          "GARD:0018901",
          "MEDGEN:124635",
          "MESH:C562729",
          "MESH:D000077277",
          "NCIT:C4024",
          "ONCOTREE:ESCC",
          "Orphanet:99977",
          "SCTID:276804009",
          "UMLS:C0279626",
          "icd11.foundation:1417891145"
        ],
        "synonyms": [
          "ESCC",
          "esophageal epidermoid carcinoma",
          "esophageal scc",
          "esophageal squamous cell cancer",
          "esophageal squamous cell carcinoma",
          "esophagus scc",
          "esophagus squamous cell carcinoma",
          "oesophagus scc",
          "scc of esophagus",
          "scc of the esophagus",
          "scc of the oesophagus",
          "squamous cell car. - esophagus",
          "squamous cell car. - oesophagus",
          "squamous cell carcinoma of esophagus",
          "squamous cell carcinoma of oesophagus",
          "squamous cell carcinoma of the esophagus",
          "squamous cell carcinoma of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC) that can affect any part of the esophagus, but is usually located in the upper or middle third."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005580"
    },
    {
      "id": 7640,
      "label": "squamous cell breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7629
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5514",
          "EFO:1000053",
          "GARD:0024277",
          "MEDGEN:233465",
          "NCIT:C5177",
          "ONCOTREE:MSCC",
          "UMLS:C1336079"
        ],
        "synonyms": [
          "breast squamous cell carcinoma",
          "primary squamous cell breast carcinoma",
          "primary squamous cell carcinoma of breast",
          "primary squamous cell carcinoma of the breast",
          "scc of breast",
          "scc of the breast",
          "squamous breast carcinoma",
          "squamous carcinoma of breast",
          "squamous carcinoma of the breast",
          "squamous cell breast carcinoma",
          "squamous cell carcinoma of breast",
          "squamous cell carcinoma of the breast",
          "metaplastic squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A rare carcinoma that arises from the breast parenchyma and is entirely composed of squamous cells."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006056"
    },
    {
      "id": 7652,
      "label": "adenosquamous carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4830",
          "EFO:1000073",
          "ICDO:8560/3",
          "MEDGEN:104901",
          "MESH:D018196",
          "NCIT:C3727",
          "SCTID:403902008",
          "UMLS:C0206623",
          "icd11.foundation:1793155313"
        ],
        "synonyms": [
          "adenosquamous carcinoma",
          "adenosquamous carcinoma (morphologic abnormality)",
          "carcinoma, adenosquamous, malignant",
          "mixed adenocarcinoma and epidermoid carcinoma",
          "mixed adenocarcinoma and epidermoid cell carcinoma",
          "mixed adenocarcinoma and squamous carcinoma",
          "mixed adenocarcinoma and squamous cell carcinoma"
        ],
        "definition": "A carcinoma composed of malignant glandular cells and malignant squamous cells."
      },
      "child_count": 15,
      "reference_id": "MONDO:0006074"
    },
    {
      "id": 7706,
      "label": "cervical squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        6855
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3744",
          "EFO:1000172",
          "GARD:0020487",
          "MEDGEN:124644",
          "NCIT:C4028",
          "ONCOTREE:CESC",
          "Orphanet:213767",
          "SCTID:254886006",
          "UMLS:C0279671",
          "icd11.foundation:1544785014"
        ],
        "synonyms": [
          "cervical squamous cell cancer",
          "cervical squamous cell carcinoma",
          "cervix squamous cell carcinoma",
          "cervix uteri squamous cell carcinoma",
          "squamous cell carcinoma of cervix",
          "squamous cell carcinoma of cervix uteri",
          "squamous cell carcinoma of the cervix",
          "squamous cell carcinoma of the cervix uteri",
          "squamous cell carcinoma of the uterine cervix",
          "squamous cell carcinoma of uterine cervix",
          "squamous cervical cancer",
          "uterine cervix squamous cell carcinoma",
          "CESC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma arising from the cervical epithelium. It usually evolves from a precancerous cervical lesion. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors for cervical squamous cell carcinoma. The following histologic patterns have been described: conventional squamous cell carcinoma, papillary squamous cell carcinoma, transitional cell carcinoma, lymphoepithelioma-like carcinoma, verrucous carcinoma, condylomatous carcinoma and spindle cell carcinoma. Survival is most closely related to the stage of disease at the time of diagnosis."
      },
      "child_count": 14,
      "reference_id": "MONDO:0006143"
    },
    {
      "id": 7726,
      "label": "colorectal squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        21360
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000198",
          "MEDGEN:317527",
          "NCIT:C43588",
          "UMLS:C1707442"
        ],
        "synonyms": [
          "colorectal (colon or rectal) squamous cell cancer",
          "colorectal squamous cell cancer",
          "colorectal squamous cell carcinoma",
          "colorectum squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A very rare colorectal carcinoma characterized by the presence of a malignant squamous cell infiltrate."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006165"
    },
    {
      "id": 7753,
      "label": "endometrial squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4530,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5533",
          "EFO:1000240",
          "MEDGEN:234217",
          "NCIT:C8719",
          "UMLS:C1333396",
          "icd11.foundation:1130568776"
        ],
        "synonyms": [
          "endometrial squamous cell carcinoma",
          "endometrium squamous cell carcinoma",
          "squamous cell carcinoma of endometrium",
          "squamous cell carcinoma of the endometrium"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary carcinoma of the endometrium characterized by the presence of malignant squamous cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006198"
    },
    {
      "id": 7773,
      "label": "gallbladder squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5174,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5535",
          "EFO:1000267",
          "GARD:0024336",
          "MEDGEN:83539",
          "NCIT:C9170",
          "UMLS:C0279658"
        ],
        "synonyms": [
          "epidermoid carcinoma of gallbladder",
          "epidermoid carcinoma of the gallbladder",
          "epidermoid gallbladder carcinoma",
          "gall bladder squamous cell carcinoma",
          "gallbladder squamous cell cancer",
          "gallbladder squamous cell carcinoma",
          "squamous cell carcinoma of gallbladder",
          "squamous cell carcinoma of the gallbladder",
          "squamous cell gallbladder carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the gallbladder. It is composed entirely by malignant squamous epithelial cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006220"
    },
    {
      "id": 7783,
      "label": "gastric squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6695,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5516",
          "EFO:1000278",
          "GARD:0021743",
          "MEDGEN:234302",
          "NCIT:C5475",
          "Orphanet:418959",
          "SCTID:766980008",
          "UMLS:C1333789"
        ],
        "synonyms": [
          "gastric (stomach) squamous cell cancer",
          "gastric squamous cell carcinoma",
          "squamous cell carcinoma of stomach",
          "squamous cell carcinoma of the stomach",
          "stomach squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A rare carcinoma of the stomach resembling squamous cell carcinomas arising elsewhere in the body."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006230"
    },
    {
      "id": 7967,
      "label": "thyroid gland squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        16049
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000594",
          "GARD:0024423",
          "MEDGEN:328050",
          "NCIT:C46008",
          "UMLS:C1710177"
        ],
        "synonyms": [
          "squamous cell thyroid gland carcinoma",
          "thyroid gland squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rapidly growing primary carcinoma of the thyroid gland composed of malignant squamous cells. The clinical course is usually aggressive."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006467"
    },
    {
      "id": 7987,
      "label": "vaginal squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3989,
        6823,
        16597
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000620",
          "GARD:0024432",
          "MEDGEN:66775",
          "NCIT:C180915",
          "NCIT:C7736",
          "ONCOTREE:VSC",
          "SCTID:105121000119102",
          "UMLS:C0238518"
        ],
        "synonyms": [
          "carcinoma of vagina squamous cell",
          "epidermoid carcinoma of the vagina",
          "epidermoid carcinoma of vagina",
          "epidermoid cell carcinoma of the vagina",
          "epidermoid cell carcinoma of vagina",
          "squamous cell carcinoma of the vagina",
          "squamous cell carcinoma of vagina",
          "vagina epidermoid carcinoma",
          "vagina epidermoid cell carcinoma",
          "vagina squamous cell carcinoma",
          "vaginal epidermoid carcinoma",
          "vaginal epidermoid cell carcinoma",
          "vaginal squamous cell cancer",
          "vaginal squamous cell cancer, NOS",
          "vaginal squamous cell carcinoma",
          "squamous cell carcinoma of the vulva/vagina"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma arising from the vagina. Human papillomavirus infection is associated with the development of vaginal intraepithelial neoplasia and invasive squamous cell carcinoma. Signs and symptoms include painless bleeding, postcoital bleeding, and urinary tract symptoms. Morphologically it resembles squamous cell carcinomas in other anatomic sites. Radiation therapy is the preferred treatment for most cases. The prognosis is related to the stage of the disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006490"
    },
    {
      "id": 11332,
      "label": "head and neck squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4185,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5520",
          "EFO:0000181",
          "GARD:0008503",
          "MEDGEN:257911",
          "MESH:C535575",
          "MedDRA:10060121",
          "NCIT:C34447",
          "OMIM:275355",
          "ONCOTREE:HNSC",
          "Orphanet:67037",
          "SCTID:716659002",
          "UMLS:C1168401"
        ],
        "synonyms": [
          "HNSCC",
          "SCCHN",
          "craniocervical region squamous cell carcinoma",
          "head and neck squamous cell carcinoma",
          "squamous cell carcinoma of head and neck",
          "squamous cell carcinoma of the head and neck",
          "squamous cell carcinoma, head and neck, somatic",
          "carcinoma of the head and neck",
          "squamous cell carcinoma, head and neck"
        ],
        "definition": "A squamous cell carcinoma that arises from any of the following anatomic sites: lip and oral cavity, nasal cavity, paranasal sinuses, pharynx, larynx, and salivary glands."
      },
      "child_count": 26,
      "reference_id": "MONDO:0010150"
    },
    {
      "id": 16829,
      "label": "squamous cell carcinoma of the corpus uteri",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        6929,
        7594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020479",
          "MEDGEN:1633992",
          "Orphanet:213716",
          "UMLS:C4707099"
        ],
        "synonyms": [
          "body of uterus squamous cell carcinoma",
          "endometrial squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma that involves the body of uterus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016266"
    },
    {
      "id": 18435,
      "label": "squamous cell carcinoma of penis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7886
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5518",
          "GARD:0021639",
          "MEDGEN:116057",
          "NCIT:C7729",
          "ONCOTREE:PSCC",
          "Orphanet:398058",
          "SCTID:403468003",
          "UMLS:C0238348",
          "icd11.foundation:186592209"
        ],
        "synonyms": [
          "epidermoid carcinoma of penis",
          "epidermoid carcinoma of the penis",
          "epidermoid cell carcinoma of penis",
          "epidermoid cell carcinoma of the penis",
          "penile epidermoid carcinoma",
          "penile epidermoid cell carcinoma",
          "penile squamous car.(epidermoid)",
          "penile squamous carcinoma (epidermoid)",
          "penile squamous cell cancer",
          "penile squamous cell carcinoma",
          "penis squamous cell carcinoma",
          "squamous cell carcinoma of penis",
          "squamous cell carcinoma of the penis",
          "PSCC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma arising from the penis. It occurs chiefly in the squamous epithelium of the glans, coronal sulcus, and foreskin. Etiologic factors include phimosis, lichen sclerosus, smoking, ultraviolet irradiation, history of warts or condylomas, and lack of circumcision. Human papilloma virus is present in a subset of penile squamous cell carcinomas. Patients may present with an exophytic or flat ulcerative mass in the glans or a large primary tumor with inguinal nodal and skin metastases. Morphologic variants include the basaloid carcinoma, warty (condylomatous) carcinoma, verrucous carcinoma, and sarcomatoid (spindle cell) carcinoma. (WHO, 2004)"
      },
      "child_count": 10,
      "reference_id": "MONDO:0018352"
    },
    {
      "id": 18541,
      "label": "squamous cell carcinoma of the small intestine",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7176
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021764",
          "MEDGEN:313711",
          "NCIT:C43534",
          "Orphanet:423968",
          "UMLS:C1710111"
        ],
        "synonyms": [
          "small intestinal squamous cell cancer",
          "small intestinal squamous cell carcinoma",
          "small intestine squamous cell carcinoma",
          "squamous cell carcinoma of the small bowel"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the small intestine. It is composed of malignant squamous cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0018509"
    },
    {
      "id": 18547,
      "label": "squamous cell carcinoma of pancreas",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        6912
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080323",
          "GARD:0021776",
          "MEDGEN:393937",
          "NCIT:C173813",
          "Orphanet:424039",
          "UMLS:C2675993"
        ],
        "synonyms": [
          "pancreas squamous cell carcinoma",
          "pancreatic squamous cell carcinoma",
          "squamous cell carcinoma of the pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma that involves the pancreas."
      },
      "child_count": 2,
      "reference_id": "MONDO:0018521"
    },
    {
      "id": 18553,
      "label": "squamous cell carcinoma of liver and intrahepatic biliary tract",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        18551
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021789",
          "MEDGEN:1668494",
          "Orphanet:424975",
          "UMLS:C4749400"
        ],
        "synonyms": [
          "squamous cell carcinoma of liver and IBT"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Squamous cell carcinoma of liver and intrahepatic biliary tract is an extremely rare, primary, malignant liver and biliray tract epithelial tumor originating in the intrahepatic bile duct epithelium histologically characterized by the presence of keratinization and/or intracellular bridges. Patients typically present abdominal pain in the right upper quadrant, jaundice, nausea, vomiting, anorexia, weight loss, fever and/or dyspepsia."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018534"
    },
    {
      "id": 20071,
      "label": "human papillomavirus-related squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        17658
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025201",
          "MEDGEN:272726",
          "NCIT:C27683",
          "UMLS:C1334057"
        ],
        "synonyms": [
          "HPV-related squamous cell carcinoma",
          "human papilloma virus related squamous cell carcinoma",
          "human papilloma virus-related squamous cell carcinoma",
          "human papillomavirus-related squamous cell carcinoma"
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0020657"
    },
    {
      "id": 20715,
      "label": "sarcomatoid squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        7925
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:199.1",
          "ICDO:8074/3",
          "NCIT:C27084",
          "SCTID:403900000"
        ],
        "synonyms": [
          "epidermoid spindle cell carcinoma",
          "sarcomatoid squamous cell carcinoma",
          "spindle cell (sarcomatoid) squamous cell carcinoma",
          "squamous cell carcinoma, sarcomatoid",
          "squamous cell carcinoma, spindle cell",
          "squamous cell spindle cell carcinoma"
        ],
        "definition": "A poorly differentiated squamous cell carcinoma characterized by the presence of malignant cells with spindle cell features."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021663"
    },
    {
      "id": 21524,
      "label": "vulvar squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4318,
        6823,
        6931
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2101",
          "EFO:1000624",
          "GARD:0022005",
          "MEDGEN:79201",
          "NCIT:C4052",
          "Orphanet:494448",
          "SCTID:254895003",
          "UMLS:C0280856",
          "icd11.foundation:146824338"
        ],
        "synonyms": [
          "epidermoid carcinoma of the vulva",
          "epidermoid carcinoma of vulva",
          "epidermoid cell carcinoma of the vulva",
          "epidermoid cell carcinoma of vulva",
          "mammalian vulva squamous cell carcinoma",
          "squamous cell carcinoma of the vulva",
          "squamous cell carcinoma of vulva",
          "vulva epidermoid carcinoma",
          "vulva epidermoid cell carcinoma",
          "vulva squamous cell carcinoma",
          "vulvar epidermoid carcinoma",
          "vulvar epidermoid cell carcinoma",
          "vulvar squamous cell cancer",
          "vulvar squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An invasive squamous cell carcinoma arising from the vulva. Risk factors include the human papilloma virus and cigarette smoking. Precursor lesions include the vulvar intraepithelial neoplasia, lichen sclerosus with associated squamous cell hyperplasia, and chronic granulomatous vulvar disease such as granuloma inguinale. Symptoms include vulvar pruritus or irritation, discharge, bleeding, and pain. The following morphologic variants have been identified: keratinizing, non-keratinizing, basaloid, warty, verrucous, keratoacanthoma-like, and squamous cell carcinoma with tumor giant cells. Risk factors for recurrence include advanced stage, tumor diameter greater than 2.5 cm, multifocality, capillary-like space involvement, associated vulvar intraepithelial neoplasia grades 2 or 3, and margins of resection involved by tumor. (WHO, 2003)"
      },
      "child_count": 18,
      "reference_id": "MONDO:0024609"
    },
    {
      "id": 23474,
      "label": "metastatic squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        21603
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:90749",
          "NCIT:C4104",
          "SCTID:403906006",
          "UMLS:C0334246"
        ],
        "synonyms": [
          "Metastatic squamous cell carcinoma"
        ],
        "definition": "A squamous cell carcinoma which has spread from its original site of growth to another anatomic site."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044907"
    },
    {
      "id": 26264,
      "label": "pure squamous carcinoma of the urothelial tract",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        23006
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:695023"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0979280"
    }
  ],
  "roots": [
    {
      "id": 4600,
      "label": "squamous cell neoplasm"
    },
    {
      "id": 6734,
      "label": "carcinoma"
    }
  ]
}