{
  "id": 6839,
  "label": "bacterial infectious disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005113",
  "properties": {
    "xrefs": [
      "DOID:104",
      "EFO:0000771",
      "ICD9:040.89",
      "ICD9:041.89",
      "ICD9:041.9",
      "MEDGEN:14012",
      "MESH:D001424",
      "NCIT:C2890",
      "SCTID:87628006",
      "UMLS:C0004623"
    ],
    "synonyms": [
      "Bacteria caused disease or disorder",
      "Bacteria disease or disorder",
      "Bacteria infectious disease",
      "bacterial disease",
      "bacterial disorder",
      "bacterial infection",
      "bacterial infectious disease",
      "infection, bacterial",
      "infections, bacterial"
    ],
    "definition": "An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 52,
  "parents": [
    {
      "id": 7200,
      "label": "infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050117",
          "EFO:0005741",
          "ICD10CM:A00-B99",
          "ICD9:079.0",
          "ICD9:136.8",
          "ICD9:136.9",
          "IDO:0000436",
          "MEDGEN:1057",
          "MESH:D003141",
          "NCIT:C26726",
          "SCTID:40733004",
          "UMLS:C0009450"
        ],
        "synonyms": [
          "communicable disease",
          "infection",
          "infectious",
          "infectious disease",
          "infectious diseases and manifestations",
          "infectious disorder",
          "transmissible disease",
          "clinical infection",
          "disease by infectious agent"
        ],
        "definition": "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact."
      },
      "child_count": 35,
      "reference_id": "MONDO:0005550"
    }
  ],
  "children": [
    {
      "id": 2837,
      "label": "primary bacterial infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050338"
        ]
      },
      "child_count": 37,
      "reference_id": "MONDO:0000314"
    },
    {
      "id": 2838,
      "label": "commensal bacterial infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050339"
        ],
        "synonyms": [
          "opportunistic bacterial infectious disease"
        ],
        "definition": "A bacterial infectious disease that results in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000315"
    },
    {
      "id": 2839,
      "label": "opportunistic bacterial infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050340"
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0000316"
    },
    {
      "id": 2898,
      "label": "chorioamnionitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839,
        20399,
        23509
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050697",
          "ICD10CM:O41.12",
          "MEDGEN:3056",
          "MESH:D002821",
          "NCIT:C26720",
          "SCTID:11612004",
          "UMLS:C0008495"
        ],
        "synonyms": [
          "fetal membrane inflammation",
          "foetal membrane inflammation",
          "inflammation of fetal membrane",
          "inflammation of foetal membrane",
          "intra-amniotic infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic finding indicating inflammation of the fetal sac membranes. It is characterized by neutrophilic infiltration of the amnion and chorion."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000409"
    },
    {
      "id": 3094,
      "label": "Clostridium difficile colitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839,
        7625
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060185",
          "MEDGEN:65946",
          "MESH:D004761",
          "MedDRA:10009657",
          "NCIT:C35286",
          "SCTID:423590009",
          "UMLS:C0238106"
        ],
        "synonyms": [
          "C. diff colitis",
          "C. diff infection",
          "Clostridioides difficile caused colitis (disease)",
          "Clostridioides difficile colitis (disease)",
          "Clostridium difficile infection",
          "pseudomembranous colitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A bacterial infection of the colon secondary to infection with Clostridium difficile bacteria. This infection generally results from the loss of normal gut flora secondary to recent antibiotic use, and manifests as copious watery stools, with associated abdominal pain and myalgia. C. difficile is the most common cause of pseudomembranous colitis, and can progress to toxic megacolon if left untreated."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000705"
    },
    {
      "id": 4856,
      "label": "bacterial gastritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6709,
        6839,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4033",
          "MEDGEN:182680",
          "NCIT:C27340",
          "SCTID:723096000",
          "UMLS:C0948039"
        ],
        "synonyms": [
          "Bacteria caused gastritis (disease)",
          "Bacteria gastritis (disease)",
          "bacterial gastritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Gastritis resulting from bacteria."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002842"
    },
    {
      "id": 6276,
      "label": "bacterial arthritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        23059
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:813",
          "EFO:1001351",
          "GARD:0027681",
          "ICD9:711.0",
          "ICD9:711.40",
          "ICD9:711.9",
          "ICD9:711.90",
          "ICD9:711.91",
          "ICD9:711.92",
          "ICD9:711.93",
          "ICD9:711.94",
          "ICD9:711.95",
          "ICD9:711.96",
          "ICD9:711.97",
          "MEDGEN:308434",
          "MESH:D001170",
          "NANDO:2200437",
          "NCIT:C26699",
          "SCTID:48245008",
          "UMLS:C1692886"
        ],
        "synonyms": [
          "infectious arthritis",
          "pyogenic arthritis",
          "septic arthritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "The inflammation of one or more joints caused by a bacterial infection within the joint space. Symptoms include pain, stiffness, and decreased range of motion in the affected joint."
      },
      "child_count": 12,
      "reference_id": "MONDO:0004471"
    },
    {
      "id": 6438,
      "label": "bacterial pneumonia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        6953
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:874",
          "EFO:1001272",
          "ICD9:482.89",
          "ICD9:482.9",
          "MEDGEN:484",
          "MESH:D018410",
          "NCIT:C26704",
          "SCTID:53084003",
          "UMLS:C0004626",
          "icd11.foundation:1323682030"
        ],
        "synonyms": [
          "Bacteria caused pneumonia",
          "Bacteria pneumonia",
          "pneumonia due to other gram-negative bacteria"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Acute infection of the lung parenchyma caused by bacteria (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila). Signs and symptoms include productive cough, fever, chills, shortness of breath, and chest pain."
      },
      "child_count": 16,
      "reference_id": "MONDO:0004652"
    },
    {
      "id": 6842,
      "label": "Whipple disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6756,
        6839,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8476",
          "EFO:0000775",
          "GARD:0007889",
          "ICD10CM:K90.81",
          "ICD9:040.2",
          "MEDGEN:7347",
          "MESH:D008061",
          "MedDRA:10047931",
          "NCIT:C85228",
          "NORD:1850",
          "Orphanet:3452",
          "SCTID:41545003",
          "UMLS:C0023788",
          "icd11.foundation:1131038233"
        ],
        "synonyms": [
          "Tropheryma whipplei caused disease or disorder",
          "Tropheryma whipplei disease or disorder",
          "Tropheryma whipplei infectious disease",
          "Whipple disease",
          "intestinal lipodystrophy",
          "intestinal lipophagic granulomatosis",
          "secondary non-tropical sprue",
          "Tropheryma whippelii infection",
          "Whipple's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A systemic infection caused by the Gram-positive bacterium Tropheryma whipplei. It affects the small intestine resulting in malabsorption. Other sites or systems affected by the infection are the joints, central nervous system, and the cardiovascular system."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005116"
    },
    {
      "id": 6843,
      "label": "Aeromonas hydrophila infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000776"
        ],
        "synonyms": [
          "Aeromonas hydrophila caused disease or disorder",
          "Aeromonas hydrophila disease or disorder"
        ],
        "definition": "Aeromonas hydrophila infection is a bacterial disease caused by infection from the Aeromonas hydrophila bacteria."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005117"
    },
    {
      "id": 6848,
      "label": "Pectobacterium carotovorum infection",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000781",
          "Wikipedia:Pectobacterium_carotovorum"
        ],
        "synonyms": [
          "Pectobacterium caused disease or disorder",
          "Pectobacterium disease or disorder",
          "Pectobacterium infectious disease"
        ],
        "definition": "A bacterial infection induced by Pectobacterium carotovorum which is is a bacterium of the family Enterobacteriaceae. This bacterius is a ubiquitous plant pathogen with a wide host range (carrot, potato, tomato, leafy greens, squash and other cucurbits, onion, green peppers, African violets etc.), able to cause disease in almost any plant tissue it invades. It is a very economically important pathogen in terms of postharvest losses, and a common cause of decay in stored fruits and vegetables. Decay caused by E. carotovora is often simply referred to as \"bacterial soft rot\" (BSR) though this may also be caused by other bacteria. Most plants or plant parts can resist invasion by the bacteria, unless some type of wound is present. High humidity and temperatures around 30°C favor development of decay. Mutants can be produced which are less virulent. Virulence factors include: pectinases, cellulases, (which degrade plant cell walls), and also proteases, lipases, xylanases and nucleases (along with the normal virulence factors for pathogens – Fe acquisition, LPS integrity, multiple global regulatory systems)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005122"
    },
    {
      "id": 6865,
      "label": "Pseudomonas infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0001076",
          "ICD9:041.7",
          "MEDGEN:10993",
          "MESH:D011552",
          "SCTID:63398001",
          "UMLS:C0033817"
        ],
        "synonyms": [
          "Pseudomonas caused disease or disorder",
          "Pseudomonas disease or disorder",
          "Pseudomonas infectious disease"
        ],
        "definition": "Infections with bacteria of the genus pseudomonas."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005141"
    },
    {
      "id": 6915,
      "label": "septic peritonitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6323,
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0002623",
          "MEDGEN:574434",
          "PMID:22911262",
          "UMLS:C0341503",
          "Wikipedia:Septic_peritonitis",
          "icd11.foundation:1560416608"
        ],
        "definition": "Septic peritonitis is an inflammatory condition of the peritoneum that occurs secondary to microbial contamination. This clinically important condition has a wide variety of clinical courses as well as high morbidity and mortality due to secondary multiorgan dysfunction. This article reviews the etiology and pathophysiology of this condition and its diagnosis in small animals; a companion article addresses treatment and prognosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005195"
    },
    {
      "id": 6940,
      "label": "bacterial infectious disease with sepsis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        29246
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0040085",
          "EFO:0003033",
          "ICD9:790.7",
          "MEDGEN:482",
          "MESH:D016470",
          "SCTID:5758002",
          "UMLS:C0004610",
          "Wikipedia:Bacteremia"
        ],
        "synonyms": [
          "Bacteremias",
          "bacteremia",
          "symptomatic bacteremia",
          "bacterial sepsis"
        ],
        "definition": "An infectious disease caused by bacteria causing sepsis."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005229"
    },
    {
      "id": 6949,
      "label": "empyema",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003097",
          "ICD9:510",
          "MEDGEN:8597",
          "MESH:D004653",
          "NCIT:C34572",
          "SCTID:312682007",
          "UMLS:C0014009"
        ],
        "synonyms": [
          "collection of pus"
        ],
        "definition": "An accumulation of pus in a body cavity, usually the pleural space."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005242"
    },
    {
      "id": 6952,
      "label": "bacterial urinary tract infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        24067
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:599.0",
          "MEDGEN:675826",
          "NCIT:C50791",
          "SCTID:68566005",
          "UMLS:C0729524"
        ],
        "synonyms": [
          "UTI",
          "infection, urinary tract",
          "tract, infection of urinary",
          "urinary tract infection",
          "urinary tract infection (disease)",
          "urinary tract infectious disease",
          "bacterial urinary tract infection (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A bacterial infectious process affecting any part of the urinary tract, most commonly the bladder and the urethra. Symptoms include urinary urgency and frequency, burning sensation during urination, lower abdominal discomfort, and cloudy urine."
      },
      "child_count": 16,
      "reference_id": "MONDO:0005247"
    },
    {
      "id": 7014,
      "label": "bacterial sexually transmitted disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        20726
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003955",
          "MEDGEN:20728",
          "MESH:D015231",
          "UMLS:C0036917"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Bacterial diseases that are potentially transmitted or propagated by sexual conduct."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005323"
    },
    {
      "id": 7054,
      "label": "meningococcal infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004249",
          "GARD:0009547",
          "ICD10CM:A39",
          "ICD10WHO:A39",
          "ICD9:036",
          "ICD9:036.89",
          "ICD9:036.9",
          "MEDGEN:7537",
          "MESH:D008589",
          "SCTID:23511006",
          "UMLS:C0025303"
        ],
        "synonyms": [
          "Neisseria meningitidis infection",
          "infections, Neisseria meningitidis",
          "meningococcal disease"
        ],
        "definition": "Infections with bacteria of the species neisseria meningitidis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005373"
    },
    {
      "id": 7504,
      "label": "pasteurellosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11055",
          "EFO:0007424",
          "ICD10CM:A28.0",
          "ICD9:027.2",
          "MEDGEN:10598",
          "MESH:D010326",
          "SCTID:83172007",
          "UMLS:C0030636",
          "icd11.foundation:304649065"
        ],
        "synonyms": [
          "Pasteurella caused disease or disorder",
          "Pasteurella disease or disorder",
          "Pasteurella infection"
        ],
        "definition": "Infections with bacteria of the genus pasteurella."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005901"
    },
    {
      "id": 7508,
      "label": "peritonsillar abscess",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839,
        6939,
        20028,
        23494
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007429",
          "ICD10CM:J36",
          "ICD10WHO:J36",
          "ICD9:475",
          "MEDGEN:45819",
          "MESH:D000039",
          "NCIT:C128322",
          "SCTID:15033003",
          "UMLS:C0031157",
          "icd11.foundation:1782446047"
        ],
        "synonyms": [
          "quinsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "An abscess that develops in the space surrounding one or both palatine tonsils."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005906"
    },
    {
      "id": 7526,
      "label": "pneumonic pasteurellosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007449",
          "MEDGEN:11408",
          "MESH:D012766",
          "UMLS:C0036969"
        ],
        "definition": "Bovine respiratory disease found in animals that have been shipped or exposed to cattle recently transported. The major agent responsible for the disease is mannheimia haemolytica and less commonly, pasteurella multocida or haemophilus somnus. All three agents are normal inhabitants of the bovine nasal pharyngeal mucosa but not the lung. They are considered opportunistic pathogens following stress, physiological and/or a viral infection. The resulting bacterial fibrinous bronchopneumonia is often fatal."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005925"
    },
    {
      "id": 7582,
      "label": "tracheitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4630,
        6839,
        20016,
        20781,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9392",
          "EFO:0007518",
          "ICD10CM:J04.1",
          "ICD9:464.1",
          "MEDGEN:11870",
          "MESH:D014136",
          "NCIT:C78643",
          "SCTID:62994001",
          "UMLS:C0040584"
        ],
        "synonyms": [
          "acute tracheitis",
          "inflammation of tracheal mucosa",
          "tracheal Inflammation",
          "tracheal mucosa inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A tracheal disease which involves bacterial infection of the trachea often caused by Staphylococcus aureus and streptococci that follows a recent viral upper respiratory infection. The symptoms include barking croup cough, loud squeaking noise while breathing, scratchy feeling in the throat, high fever, and production of large amounts of pus-filled secretions."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005990"
    },
    {
      "id": 8108,
      "label": "Actinobacillus infectious disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D000189"
        ],
        "synonyms": [
          "Actinobacillus caused disease or disorder",
          "Actinobacillus disease or disorder",
          "Actinobacillus infection",
          "infection, Actinobacillus",
          "infections, Actinobacillus"
        ],
        "definition": "Infections with bacteria of the genus actinobacillus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006636"
    },
    {
      "id": 8137,
      "label": "bacterial conjunctivitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5674,
        6839,
        23257
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9700",
          "EFO:1000829",
          "ICD9:372.03",
          "MEDGEN:3209",
          "MESH:D003234",
          "MedDRA:10061784",
          "NCIT:C53656",
          "SCTID:243321006",
          "UMLS:C0009768",
          "icd11.foundation:902481358"
        ],
        "synonyms": [
          "Bacteria caused conjunctival disease",
          "Bacteria conjunctival disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Inflammation of the conjunctiva caused by a variety of bacterial agents."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006668"
    },
    {
      "id": 8138,
      "label": "bacterial endocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2995,
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000830",
          "GARD:0024456",
          "HP:0006689",
          "MEDGEN:41779",
          "MESH:D004697",
          "MedDRA:10004019",
          "NCIT:C128359",
          "SCTID:301183007",
          "UMLS:C0014121",
          "icd11.foundation:1924438986"
        ],
        "synonyms": [
          "Bacteria caused endocarditis (disease)",
          "Bacteria endocarditis (disease)",
          "bacterial endocarditis",
          "bacterial endocarditis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Endocarditis that is caused by an infection with a bacterial agent."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006669"
    },
    {
      "id": 8139,
      "label": "bacterial meningitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6561,
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9470",
          "EFO:1000831",
          "GARD:0005881",
          "ICD9:320",
          "ICD9:320.7",
          "ICD9:320.89",
          "ICD9:320.9",
          "MEDGEN:39048",
          "MESH:D016920",
          "MedDRA:10004049",
          "NCIT:C118297",
          "SCTID:95883001",
          "UMLS:C0085437",
          "icd11.foundation:684930313"
        ],
        "synonyms": [
          "Bacteria caused infectious meningitis",
          "Bacteria infectious meningitis",
          "meningitis, bacterial"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Inflammation of the membranes surrounding the brain and spinal cord due to a bacterial infection."
      },
      "child_count": 16,
      "reference_id": "MONDO:0006670"
    },
    {
      "id": 8168,
      "label": "Bifidobacteriales infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:209748",
          "MESH:D039941",
          "UMLS:C1136339"
        ],
        "synonyms": [
          "Bifidobacteriales caused disease or disorder",
          "Bifidobacteriales disease or disorder",
          "Bifidobacteriales infection",
          "infection, Bifidobacteriales",
          "infections, Bifidobacteriales"
        ],
        "definition": "Infections with BACTERIA of the order Bifidobacteriales. This includes infections in the genera BIFIDOBACTERIUM and GARDNERELLA, in the family Bifidobacteriaceae."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006706"
    },
    {
      "id": 8359,
      "label": "haemophilus infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001127",
          "MESH:D006192",
          "NCIT:C34654",
          "SCTID:41659003"
        ],
        "synonyms": [
          "Haemophilus caused disease or disorder",
          "Haemophilus disease or disorder",
          "Haemophilus infectious disease",
          "haemophilus infectious disease",
          "Haemophilus infection",
          "Hemophilus infection",
          "Hemophilus infections",
          "infection, Haemophilus",
          "infection, Hemophilus",
          "infections, Haemophilus",
          "infections, Hemophilus"
        ],
        "definition": "Infections with bacteria of the genus haemophilus."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006926"
    },
    {
      "id": 8361,
      "label": "Proteus infectious disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:46164",
          "MESH:D011512",
          "SCTID:186437007",
          "UMLS:C0033700"
        ],
        "synonyms": [
          "Proteus <enterobacteria> caused disease or disorder",
          "Proteus <enterobacteria> disease or disorder",
          "Proteus <enterobacteria> infectious disease",
          "Proteus infection",
          "infection, Proteus",
          "infections, Proteus"
        ],
        "definition": "Infections with bacteria of the genus proteus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006929"
    },
    {
      "id": 8368,
      "label": "pulpitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5326,
        6839,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11121",
          "EFO:1001139",
          "ICD10CM:K04.0",
          "ICD9:522.0",
          "MEDGEN:19580",
          "MESH:D011671",
          "MedDRA:10037463",
          "SCTID:32620007",
          "UMLS:C0034103",
          "icd11.foundation:576344431"
        ],
        "synonyms": [
          "dental pulp inflammation",
          "inflammation of dental pulp"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Inflammation of the dental pulp."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006937"
    },
    {
      "id": 8372,
      "label": "rat-bite fever",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001144",
          "GARD:0009557",
          "ICD9:026.9",
          "MEDGEN:11123",
          "MESH:D011906",
          "MedDRA:10037904",
          "NCIT:C34971",
          "Orphanet:31205",
          "SCTID:1685005",
          "UMLS:C0034686",
          "icd11.foundation:1026551291"
        ],
        "synonyms": [
          "Streptobacillosis",
          "spirillosis",
          "rat bite fever"
        ],
        "definition": "An infectious disease that is caused transmitted by the bite of a rat. Two species of bacteria can cause the infection: Streptobacillus moniliformis and Spirillum minus."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006941"
    },
    {
      "id": 8384,
      "label": "Rickettsiosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001162",
          "GARD:0019827",
          "ICD10CM:A75-A79",
          "ICD9:083.9",
          "MEDGEN:20584",
          "MESH:D012282",
          "MedDRA:10061495",
          "NCIT:C34991",
          "Orphanet:102021",
          "SCTID:37246009",
          "UMLS:C0035585"
        ],
        "synonyms": [
          "Rickettsia caused disease or disorder",
          "Rickettsia disease or disorder",
          "Rickettsia infection",
          "Rickettsia infectious disease",
          "Rickettsiae disease",
          "Rickettsial disease",
          "Rickettsial infectious disease",
          "Rickettsial infectious disorder",
          "Rickettsiosis",
          "infection, Rickettsia",
          "infections, Rickettsia"
        ],
        "definition": "A group of infectious diseases that is caused by Rickettsia."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006956"
    },
    {
      "id": 8435,
      "label": "vibrio infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001235",
          "MEDGEN:53010",
          "MESH:D014735",
          "UMLS:C0042636"
        ],
        "synonyms": [
          "Vibrio caused disease or disorder",
          "Vibrio disease or disorder",
          "Vibrio infectious disease",
          "vibrio infectious disease"
        ],
        "definition": "Infections with bacteria of the genus vibrio."
      },
      "child_count": 2,
      "reference_id": "MONDO:0007014"
    },
    {
      "id": 8443,
      "label": "Yersinia infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001245",
          "MESH:D015009",
          "NCIT:C128337",
          "SCTID:83436008"
        ],
        "synonyms": [
          "Yersinia <bacteria> infection",
          "yersiniosis",
          "Yersinia infection",
          "infection, Yersinia",
          "infections, Yersinia",
          "infections, Yersinia <bacteria>"
        ],
        "definition": "Infections with bacteria of the genus yersinia."
      },
      "child_count": 3,
      "reference_id": "MONDO:0007023"
    },
    {
      "id": 16740,
      "label": "bacterial myositis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        20400
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020378",
          "MEDGEN:538237",
          "Orphanet:206994",
          "SCTID:30330001",
          "UMLS:C0263979",
          "icd11.foundation:1277815767"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0016127"
    },
    {
      "id": 17492,
      "label": "noma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6605,
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9672",
          "EFO:1001063",
          "GARD:0004001",
          "ICD10CM:A69.0",
          "ICD9:528.1",
          "MEDGEN:10366",
          "MESH:D009625",
          "MedDRA:10029502",
          "NCIT:C34852",
          "Orphanet:2700",
          "SCTID:18116006",
          "UMLS:C0028271",
          "icd11.foundation:340823130"
        ],
        "synonyms": [
          "cancrum oris",
          "gangrenous stomatitis",
          "noma neonatorum",
          "oral gangrene",
          "oro-facial gangrene",
          "oro-facial noma"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Noma is a gangrenous disease that causes severe destruction of the soft and osseous tissues of the face."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017124"
    },
    {
      "id": 18267,
      "label": "idiopathic severe pneumococcemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6839,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:35065"
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018111"
    },
    {
      "id": 18604,
      "label": "necrotizing soft tissue infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021839",
          "ICD9:136.9",
          "ICD9:729.99",
          "MEDGEN:752585",
          "Orphanet:440368",
          "SCTID:443928008",
          "UMLS:C2732890"
        ],
        "synonyms": [
          "NSTI"
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0018602"
    },
    {
      "id": 20027,
      "label": "mycobacterial infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:6479",
          "MESH:D009164",
          "NCIT:C26831",
          "SCTID:88415009",
          "UMLS:C0026918"
        ],
        "synonyms": [
          "mycobacterial infection",
          "mycobacteriosis",
          "mycobacterium infection"
        ],
        "definition": "Infection due to organisms from the genus Mycobacteria."
      },
      "child_count": 7,
      "reference_id": "MONDO:0020590"
    },
    {
      "id": 20243,
      "label": "escherichia coli infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001318",
          "GTR:AN0474198",
          "GTR:AN0485754",
          "GTR:AN0485755",
          "HP:0002740",
          "MEDGEN:4543",
          "MESH:D004927",
          "NCIT:C34594",
          "SCTID:71057007",
          "UMLS:C0014836"
        ],
        "synonyms": [
          "e coli infection",
          "escherichia coli infection",
          "Bacterial infection caused by E. coli",
          "Bacterial infection due to E. coli",
          "Colibacillosis",
          "E COLI INFECT",
          "E Coli Infection",
          "E coli Infection",
          "E coli Infections",
          "E coli infections",
          "E coli infections, recurrent",
          "E. coli Infection",
          "E. coli Infections",
          "E. coli infection",
          "ESCHERICHIA COLI INFECT",
          "Escherichia Coli Infection",
          "Escherichia coli Infection",
          "Escherichia coli Infections",
          "Escherichia coli infection",
          "INFECT E COLI",
          "INFECT ESCHERICHIA COLI",
          "Infection caused by Escherichia coli",
          "Infection due to Escherichia coli",
          "Infection, E coli",
          "Infection, E. coli",
          "Infection, Escherichia coli",
          "Infections, E coli",
          "Infections, Escherichia coli",
          "Recurrent E. coli infections"
        ],
        "definition": "Infection with the organism Escherichia Coli."
      },
      "child_count": 1,
      "reference_id": "MONDO:0020920"
    },
    {
      "id": 20723,
      "label": "gram-negative bacterial infections",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:041.85",
          "MEDGEN:88406",
          "MESH:D016905",
          "SCTID:371583007",
          "UMLS:C0085423"
        ],
        "synonyms": [
          "bacterial infection, gram-negative",
          "bacterial infections, gram negative",
          "bacterial infections, gram-negative",
          "bacterial infections, gramme negative",
          "gram negative bacterial infections",
          "gram-negative bacterial infection",
          "gramme negative bacterial infections",
          "infection, gram-negative bacterial",
          "infections, gram negative bacterial",
          "infections, gram-negative bacterial",
          "infections, gramme negative bacterial"
        ],
        "definition": "Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method."
      },
      "child_count": 15,
      "reference_id": "MONDO:0021678"
    },
    {
      "id": 20724,
      "label": "gram-positive bacterial infections",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:041.89",
          "MEDGEN:39283",
          "MESH:D016908",
          "SCTID:371582002",
          "UMLS:C0085426"
        ],
        "synonyms": [
          "Gram Positive bacterial infections",
          "Gram-positive bacterial infection",
          "Gramme Positive bacterial infections",
          "bacterial infection, Gram-positive",
          "bacterial infections, Gram Positive",
          "bacterial infections, Gram-positive",
          "bacterial infections, Gramme Positive",
          "infection, Gram-positive bacterial",
          "infections, Gram Positive bacterial",
          "infections, Gram-positive bacterial",
          "infections, Gramme Positive bacterial"
        ],
        "definition": "Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021679"
    },
    {
      "id": 20765,
      "label": "spirochaetales infections",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009567",
          "MEDGEN:11556",
          "MESH:D013145",
          "UMLS:C0037974"
        ],
        "synonyms": [
          "INFECT SPIROCHAETALES",
          "INFECT SPIROCHETE",
          "Infection, Spirochaetales",
          "Infection, Spirochete",
          "Infections, Spirochaetales",
          "Infections, Spirochete",
          "SPIROCHAETALES INFECT",
          "SPIROCHETE INFECT",
          "Spirochaetales Infection",
          "Spirochaetales Infections",
          "Spirochetal infection",
          "Spirochete Infection",
          "Spirochete Infections",
          "Spirochetosis"
        ],
        "definition": "Infections with bacteria of the order SPIROCHAETALES."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021839"
    },
    {
      "id": 21329,
      "label": "skin disease caused by bacterial infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D017192"
        ],
        "synonyms": [
          "Bacteria caused skin disease caused by infection",
          "Bacteria skin disease caused by infection",
          "bacterial skin disease",
          "bacterial skin diseases",
          "disease, bacterial skin",
          "diseases, bacterial skin",
          "skin disease, bacterial"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Skin diseases caused by bacteria."
      },
      "child_count": 34,
      "reference_id": "MONDO:0024295"
    },
    {
      "id": 21346,
      "label": "staphylococcal infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001849",
          "MEDGEN:52483",
          "MESH:D013203",
          "NCIT:C35038",
          "SCTID:56038003",
          "UMLS:C0038160"
        ],
        "synonyms": [
          "staphylococcal infection"
        ],
        "definition": "An infection caused by Staphylococcus."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024313"
    },
    {
      "id": 21395,
      "label": "anaerobic bacteria infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:041.84",
          "MEDGEN:678527",
          "SCTID:423451008",
          "UMLS:C0854328"
        ],
        "synonyms": [
          "anaerobic bacterial infection",
          "infection caused by anaerobic bacteria",
          "infection due to anaerobic bacteria"
        ]
      },
      "child_count": 10,
      "reference_id": "MONDO:0024389"
    },
    {
      "id": 21982,
      "label": "Klebsiella infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D007710",
          "SCTID:721756002"
        ],
        "synonyms": [
          "Klebsiella caused disease or disorder",
          "Klebsiella disease or disorder",
          "Klebsiella infection",
          "infection, Klebsiella",
          "infections, Klebsiella"
        ],
        "definition": "Infections with bacteria of the genus KLEBSIELLA."
      },
      "child_count": 3,
      "reference_id": "MONDO:0030603"
    },
    {
      "id": 23200,
      "label": "fournier gangrene",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5121,
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:N49.3",
          "MEDGEN:65967",
          "MESH:D018934",
          "SCTID:398318005",
          "UMLS:C0238419"
        ],
        "synonyms": [
          "fournier gangrene",
          "fournier's gangrene",
          "Fournier disease",
          "Fournier's disease",
          "Fournier's gangrene",
          "Fourniers disease",
          "Fourniers gangrene",
          "gangrene, Fournier",
          "gangrene, Fournier's"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An acute necrotic infection of the SCROTUM; PENIS; or PERINEUM. It is characterized by scrotum pain and redness with rapid progression to gangrene and sloughing of tissue. Fournier gangrene is usually secondary to perirectal or periurethral infections associated with local trauma, operative procedures, or urinary tract disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043352"
    },
    {
      "id": 24374,
      "label": "botryomycosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:L08.81",
          "MEDGEN:754315",
          "MPATH:859",
          "UMLS:C2937266"
        ],
        "synonyms": [
          "bacterial pseudomycosis",
          "pyoderma vegetans"
        ],
        "definition": "A rare chronic suppurative bacterial infection involving mostly subcutaneous tissues and less frequently other organs. Botryomycosis is mostly caused by Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa but the exact pathogenesis remains uncertain. Treatment often requires a combination of both surgical debridement and long-term antimicrobial therapy."
      },
      "child_count": 2,
      "reference_id": "MONDO:0400006"
    },
    {
      "id": 24380,
      "label": "bacterial hemorrhagic fever",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        24379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026292"
        ],
        "synonyms": [
          "bacterial haemorrhagic fever",
          "haemorrhagic fever, bacterial"
        ],
        "definition": "A hemorrhagic fever caused by bacteria. Bacterial hemorrhagic disease is rare. One example of a bacterial hemorrhagic disease is scrub typhus."
      },
      "child_count": 2,
      "reference_id": "MONDO:0600003"
    },
    {
      "id": 29222,
      "label": "Mycoplasmoides infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "mycoplasmosis",
          "mycoplasma infection"
        ],
        "definition": "A disease caused by infection with Mycoplasmoides."
      },
      "child_count": 2,
      "reference_id": "MONDO:1030003"
    },
    {
      "id": 29250,
      "label": "Enterococcus infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "Enterococcus caused disease or disorder"
        ],
        "definition": "A bacterial disease caused by infection with Enterococcus."
      },
      "child_count": 1,
      "reference_id": "MONDO:1040019"
    }
  ],
  "roots": [
    {
      "id": 7200,
      "label": "infectious disease"
    }
  ]
}