{
  "id": 6889,
  "label": "fibroma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005167",
  "properties": {
    "xrefs": [
      "DOID:0050871",
      "EFO:0002424",
      "ICD9:215.9",
      "ICDO:8810/0",
      "MEDGEN:42016",
      "MESH:D005350",
      "NCIT:C3041",
      "SCTID:424568000",
      "UMLS:C0016045"
    ],
    "synonyms": [
      "fibroma",
      "fibroma, benign"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 7762,
      "label": "fibroblastic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4667,
        20678
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000255",
          "MEDGEN:60198",
          "NCIT:C7075",
          "UMLS:C0206643"
        ],
        "synonyms": [
          "fibroblastic neoplasm",
          "fibroblastic tumor",
          "fibroblastic tumour",
          "fibrocytic neoplasm",
          "fibrocytic tumor",
          "fibrocytic tumour",
          "fibrogenic neoplasm",
          "fibrogenicTumor",
          "fibrous neoplasm",
          "fibrous tumor",
          "fibrous tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign, intermediate, or malignant mesenchymal neoplasm characterized by the presence of neoplastic fibroblasts."
      },
      "child_count": 14,
      "reference_id": "MONDO:0006209"
    }
  ],
  "children": [
    {
      "id": 6140,
      "label": "testicular fibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5102,
        6889
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7675",
          "GARD:0023936",
          "MEDGEN:308256",
          "NCIT:C39951",
          "UMLS:C1515282"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm that arises from the testis and is characterized by the presence of fusiform cells and collagenization."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004324"
    },
    {
      "id": 6484,
      "label": "liver solitary fibrous tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889,
        16812,
        21432
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:907",
          "GARD:0024092",
          "MEDGEN:232273",
          "NCIT:C5752",
          "UMLS:C1333965"
        ],
        "synonyms": [
          "fibroma of liver",
          "fibroma of the liver",
          "hepatic fibroma",
          "liver fibroma",
          "liver localised fibrous mesothelioma",
          "liver localised fibrous tumour",
          "liver localized fibrous mesothelioma",
          "liver localized fibrous tumor",
          "liver solitary fibrous tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A solitary fibrous tumor that arises from the liver. It affects females more frequently than males. Signs and symptoms include the presence of an abdominal mass and abdominal discomfort."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004705"
    },
    {
      "id": 6903,
      "label": "serous cystadenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6889
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0002510"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign neoplasm characterized by the presence of cystic structures lined by serous epithelial cells in a fibrotic stroma. Most commonly the primary site is the ovary, but serous cystadenofibromas can occur in the pancreas as well."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005182"
    },
    {
      "id": 7650,
      "label": "adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3029,
        6889
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2683",
          "EFO:1000070",
          "ICDO:9013/0",
          "MEDGEN:1325",
          "MESH:D000232",
          "NCIT:C8984",
          "UMLS:C0001422"
        ],
        "synonyms": [
          "adenofibroma, benign",
          "adenofibroma, no ICD-O subtype",
          "adenofibroma, no ICD-O subtype (morphologic abnormality)",
          "benign mixed Muellerian tumor",
          "benign mixed Muellerian tumour",
          "female reproductive system adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign neoplasm characterized by the presence of connective tissue stroma and epithelial structures. It occurs in the ovary, fallopian tube, uterine corpus, and cervix. Cases of adenofibroma of the ovary with low grade malignant potential have also been reported."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006071"
    },
    {
      "id": 7951,
      "label": "tendon sheath fibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889,
        21600
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000561",
          "ICD9:215.9",
          "MEDGEN:226901",
          "NCIT:C6485",
          "SCTID:403992002",
          "UMLS:C1275236"
        ],
        "synonyms": [
          "fibroma of tendon sheath",
          "fibroma of the tendon sheath",
          "tendon sheath fibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A small, slow growing, benign neoplasm arising from the tendon sheaths. The tumor is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006442"
    },
    {
      "id": 9222,
      "label": "uterine corpus leiomyoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3776,
        6889,
        20643,
        21247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13223",
          "EFO:0000731",
          "GARD:0024585",
          "HP:0000131",
          "ICD10CM:D25",
          "ICD9:218",
          "ICD9:218.9",
          "MEDGEN:21801",
          "NCIT:C3434",
          "OMIM:150699",
          "ONCOTREE:ULM",
          "SCTID:95315005",
          "UMLS:C0042133"
        ],
        "synonyms": [
          "body of uterus fibroid",
          "body of uterus leiomyoma",
          "corpus uteri fibroid",
          "corpus uteri leiomyoma",
          "fibroid of body of uterus",
          "fibroid of corpus uteri",
          "fibroid of the body of uterus",
          "fibroid of the corpus uteri",
          "fibroid of the uterine body",
          "fibroid of the uterine corpus",
          "fibroid of uterine body",
          "fibroid of uterine corpus",
          "leiomyoma of body of uterus",
          "leiomyoma of corpus uteri",
          "leiomyoma of the body of uterus",
          "leiomyoma of the corpus uteri",
          "leiomyoma of the uterine body",
          "leiomyoma of the uterine corpus",
          "leiomyoma of uterine body",
          "leiomyoma of uterine corpus",
          "uterine body fibroid",
          "uterine body leiomyoma",
          "uterine corpus fibroid",
          "uterine corpus leiomyoma",
          "uterine corpus leiomyomata",
          "uterine fibroid",
          "UL",
          "leiomyoma, uterine",
          "uterine leiomyoma",
          "uterus fibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern."
      },
      "child_count": 44,
      "reference_id": "MONDO:0007886"
    },
    {
      "id": 9479,
      "label": "ovarian fibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3047,
        6889
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021375",
          "HP:0010618",
          "MEDGEN:57706",
          "MESH:C562391",
          "MedDRA:10064257",
          "NCIT:C3498",
          "OMIM:166970",
          "Orphanet:314473",
          "SCTID:254865006",
          "UMLS:C0149951",
          "icd11.foundation:871413134"
        ],
        "synonyms": [
          "fibroma of ovary",
          "fibroma of the ovary",
          "ovarian fibroma",
          "ovarian fibroma (disease)",
          "ovarian fibromata"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm arising from soft tissue of the ovary. It is characterized by the presence of spindle-shaped fibroblasts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008168"
    },
    {
      "id": 16674,
      "label": "calcified aponeurotic fibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889,
        16673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020329",
          "MEDGEN:107818",
          "NCIT:C4818",
          "Orphanet:199260",
          "SCTID:703614006",
          "UMLS:C0553647"
        ],
        "synonyms": [
          "Juvenile aponeurotic fibroma",
          "Juvenile aponeurotic fibrosis",
          "Keasby tumor",
          "Keasby tumour",
          "juvenile aponeurotic fibromatosis",
          "calcifying aponeurotic fibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rare slow-growing benign neoplasm arising from the soft tissues in children. It is a poorly circumscribed tumor characterized by the presence of chondrocyte-like cells, nodular calcification, nuclear palisading, and in some cases osteoclastic giant cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016038"
    },
    {
      "id": 20648,
      "label": "fibroma of lung",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889,
        20356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:272803",
          "NCIT:C5658",
          "SCTID:707387004",
          "UMLS:C1334444"
        ],
        "synonyms": [
          "fibroma of the lung",
          "lung fibroma",
          "pulmonary fibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A fibroma that involves the lung."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021531"
    },
    {
      "id": 20649,
      "label": "fibroma of prostate",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889,
        20629
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:600.20",
          "MEDGEN:75709",
          "NCIT:C3972",
          "SCTID:47014000",
          "UMLS:C0268885"
        ],
        "synonyms": [
          "fibroma of the prostate",
          "prostate fibroma",
          "prostate gland fibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A fibroma that involves the prostate gland."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021532"
    },
    {
      "id": 25065,
      "label": "oral fibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1843431",
          "UMLS:C0948118"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A non-metastasizing oral neoplasm arising from fibrous tissue characterized by the presence of spindle-shaped fibroblasts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0800481"
    }
  ],
  "roots": [
    {
      "id": 7762,
      "label": "fibroblastic neoplasm"
    }
  ]
}