{
  "id": 6916,
  "label": "thymus neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005197",
  "properties": {
    "xrefs": [
      "EFO:0002626",
      "GARD:0019767",
      "ICD9:239.89",
      "MEDGEN:811424",
      "NCIT:C3412",
      "ONCOTREE:THYMUS",
      "Orphanet:100100",
      "SCTID:127231009",
      "UMLS:C3714644"
    ],
    "synonyms": [
      "Thymus neoplasm",
      "Thymus tumor",
      "Thymus tumour",
      "neoplasm of Thymus",
      "neoplasm of the Thymus",
      "neoplasm of thymus",
      "thymic neoplasm",
      "thymic tumor",
      "thymic tumour",
      "thymus neoplasm (disease)",
      "thymus tumor",
      "thymus tumour",
      "tumor of Thymus",
      "tumor of the Thymus",
      "tumor of thymus",
      "tumour of Thymus",
      "tumour of the Thymus",
      "tumour of thymus",
      "THYMUS"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A neoplasm that affects the thymus. Representative examples include thymoma and carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4223,
      "label": "endocrine gland neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003769",
          "ICD9:239.7",
          "MEDGEN:4044",
          "NCIT:C3010",
          "SCTID:387922007",
          "UMLS:C0014132"
        ],
        "synonyms": [
          "endocrine gland neoplasm (disease)",
          "endocrine gland tumor",
          "endocrine gland tumour",
          "endocrine neoplasm",
          "endocrine system neoplasm",
          "endocrine system tumor",
          "endocrine system tumour",
          "endocrine tumor",
          "endocrine tumour",
          "neoplasm of endocrine gland",
          "tumor of endocrine gland",
          "tumour of endocrine gland",
          "malignant endocrine tumor",
          "malignant endocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm arising from the epithelial cells of an endocrine organ. Representative examples include pituitary gland adenoma, pituitary gland carcinoma, thyroid gland carcinoma, carcinoid tumor, and neuroendocrine carcinoma."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002082"
    },
    {
      "id": 4440,
      "label": "hematopoietic and lymphoid system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2531",
          "GARD:0023120",
          "MEDGEN:268180",
          "MESH:D019337",
          "NCIT:C35813",
          "SCTID:129154003",
          "UMLS:C1512393"
        ],
        "synonyms": [
          "haematopoietic neoplasm",
          "haematopoietic neoplasm (morphologic abnormality)",
          "hematologic neoplasm",
          "hematopoietic neoplasm",
          "hematopoietic neoplasm (morphologic abnormality)",
          "blood neoplasm (disease)",
          "blood tumor",
          "blood tumour",
          "haematological tumours",
          "haematopoietic and lymphoid system tumour",
          "haematopoietic system neoplasm",
          "haematopoietic system tumour",
          "haematopoietic tumours",
          "hematopoietic and lymphoid system neoplasm",
          "hematopoietic and lymphoid system tumor",
          "hematopoietic system neoplasm",
          "hematopoietic system tumor",
          "neoplasm of blood",
          "neoplasm of haematopoietic system",
          "neoplasm of hematopoietic system",
          "tumor of blood",
          "tumor of hematopoietic system",
          "tumour of blood",
          "tumour of haematopoietic system",
          "blood cancer",
          "haematopoietic cancer",
          "hematologic malignancy",
          "hematopoietic cancer",
          "malignant haematopoietic neoplasm (morphologic abnormality)",
          "malignant hematopoietic neoplasm (morphologic abnormality)",
          "hematologic cancer",
          "malignant haematopoietic neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Neoplasms of the hematopoietic system, including hematopoietic cell neoplasms (e.g. leukemias, lymphomas) and non-hematopoietic cell neoplasms that can affect the hematopoietic system (e.g. lymph node and splenic sarcomas). --2003"
      },
      "child_count": 18,
      "reference_id": "MONDO:0002334"
    },
    {
      "id": 5325,
      "label": "thymus gland disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778,
        6875,
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:533",
          "GARD:0023497",
          "ICD9:254",
          "ICD9:254.9",
          "MEDGEN:57585",
          "NCIT:C26962",
          "SCTID:20673009",
          "UMLS:C0154199"
        ],
        "synonyms": [
          "Thymus disorder",
          "disease of thymus",
          "disease or disorder of thymus",
          "disorder of thymus",
          "disorder of thymus gland",
          "thymus disease",
          "thymus disease or disorder",
          "thymus disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the thymus. Representative examples include thymic hyperplasia, thymoma, and thymic carcinoma."
      },
      "child_count": 9,
      "reference_id": "MONDO:0003393"
    }
  ],
  "children": [
    {
      "id": 4646,
      "label": "thymus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3028,
        6916,
        20310
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3277",
          "GARD:0023177",
          "ICD10CM:C37",
          "ICD9:164.0",
          "MEDGEN:155883",
          "NCIT:C4962",
          "SCTID:363434003",
          "UMLS:C0751552",
          "icd11.foundation:1718833206"
        ],
        "synonyms": [
          "thymic neoplasm",
          "thymic tumor",
          "thymic tumour",
          "Thymus cancer",
          "cancer of Thymus",
          "cancer of the Thymus",
          "cancer of thymus",
          "malignant Thymus neoplasm",
          "malignant Thymus tumor",
          "malignant Thymus tumour",
          "malignant neoplasm of Thymus",
          "malignant neoplasm of the Thymus",
          "malignant neoplasm of thymus",
          "malignant thymus neoplasm",
          "malignant tumor of Thymus",
          "malignant tumor of the Thymus",
          "malignant tumour of Thymus",
          "malignant tumour of the Thymus",
          "thymus cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving the thymus. This category includes malignant thymomas, thymic lymphomas, primary thymic carcinomas, and metastatic carcinomas from other anatomic sites."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002586"
    },
    {
      "id": 18240,
      "label": "thymic epithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6916,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0005201",
          "MEDGEN:220416",
          "MESH:C536905",
          "NCIT:C6450",
          "ONCOTREE:TET",
          "Orphanet:3398",
          "UMLS:C1266101"
        ],
        "synonyms": [
          "TEN",
          "Thymus epithelial neoplasm",
          "Thymus epithelial tumor",
          "Thymus epithelial tumour",
          "epithelial neoplasm of Thymus",
          "epithelial neoplasm of the Thymus",
          "epithelial tumor of Thymus",
          "epithelial tumor of the Thymus",
          "epithelial tumour of Thymus",
          "epithelial tumour of the Thymus",
          "thymic epithelial tumor",
          "thymic epithelial tumour",
          "thymic epithelium neoplasm",
          "thymus epithelial neoplasm",
          "Tet",
          "thymoma, adult"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An epithelial neoplasm that affects the thymus gland. This category includes thymomas and carcinomas."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018079"
    },
    {
      "id": 19679,
      "label": "thymic neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6916,
        19314
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019361",
          "MEDGEN:234428",
          "NCIT:C6430",
          "ONCOTREE:TNET",
          "Orphanet:97289",
          "UMLS:C1336746"
        ],
        "synonyms": [
          "neuroendocrine neoplasm of thymus",
          "thymus NET",
          "thymus neuroendocrine neoplasm",
          "thymus neuroendocrine tumor",
          "thymus neuroendocrine tumor, well differentiated, low or intermediate grade",
          "thymus neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Thymic endocrine tumor is a rare, malignant, primary thymic neoplasm originating from neuroendocrine cells, presenting as a mass within the anterior mediastinum. Patients typically present with nonspecific symptoms, such as chest pain, cough, shortness of breath, or in some cases, superior vena cava syndrome, although patients could be asymptomatic during the early stages or present with multiple endocrine neoplasia type I. Ectopic production of ACTH and serotonin can lead to Cushing syndrome and carcinoid sydrome, respectively."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019964"
    },
    {
      "id": 20631,
      "label": "benign neoplasm of thymus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3032,
        3035,
        6916
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025327",
          "ICD10CM:D15.0",
          "ICD9:212.6",
          "MEDGEN:87526",
          "NCIT:C4458",
          "SCTID:92437008",
          "UMLS:C0345975",
          "icd11.foundation:1583331018"
        ],
        "synonyms": [
          "benign Thymus neoplasm",
          "benign Thymus tumor",
          "benign Thymus tumour",
          "benign neoplasm of the Thymus",
          "benign thymic neoplasm",
          "benign thymic tumor",
          "benign thymic tumour",
          "benign tumor of Thymus",
          "benign tumor of the Thymus",
          "benign tumour of Thymus",
          "benign tumour of the Thymus",
          "thymus benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the thymus."
      },
      "child_count": 3,
      "reference_id": "MONDO:0021512"
    }
  ],
  "roots": [
    {
      "id": 4223,
      "label": "endocrine gland neoplasm"
    },
    {
      "id": 4440,
      "label": "hematopoietic and lymphoid system neoplasm"
    },
    {
      "id": 5325,
      "label": "thymus gland disorder"
    }
  ]
}