{
  "id": 6927,
  "label": "ovarian serous adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005211",
  "properties": {
    "xrefs": [
      "DOID:0050933",
      "DOID:5744",
      "EFO:0002917",
      "GARD:0024164",
      "MEDGEN:233278",
      "NCIT:C7550",
      "ONCOTREE:SOC",
      "UMLS:C1335177"
    ],
    "synonyms": [
      "ovarian serous adenocarcinoma",
      "ovarian serous carcinoma",
      "ovary serous adenocarcinoma",
      "serous adenocarcinoma of ovary",
      "serous adenocarcinoma of the ovary",
      "serous carcinoma of ovary",
      "serous carcinoma of the ovary",
      "malignant ovarian serous tumour",
      "serous ovarian cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An adenocarcinoma that arises from the ovary and is characterized by the presence of malignant epithelial cells that, in well differentiated tumors, resemble the epithelium of the fallopian tube or, in poorly differentiated tumors, show anaplastic features and marked nuclear atypia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4787,
      "label": "ovarian adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6864
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3713",
          "EFO:0006460",
          "GARD:0020466",
          "MEDGEN:181757",
          "MedDRA:10051938",
          "NCIT:C7700",
          "Orphanet:213504",
          "UMLS:C0948216"
        ],
        "synonyms": [
          "adenocarcinoma of ovary",
          "adenocarcinoma of the ovary",
          "ovarian adenocarcinoma",
          "ovary adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the ovary. It is the most common type of ovarian carcinoma. It includes the serous adenocarcinoma, mucinous adenocarcinoma, clear cell adenocarcinoma, and endometrioid adenocarcinoma."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002752"
    },
    {
      "id": 6974,
      "label": "serous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3114",
          "EFO:0003825",
          "NCIT:C40101"
        ],
        "synonyms": [
          "serous adenocarcinoma",
          "serous carcinoma",
          "serous cystadenocarcinoma",
          "serous cystadenocarcinoma, NOS (morphologic abnormality)"
        ],
        "definition": "An adenocarcinoma that is characterized by the presence of papillary patterns and cellular budding. Psammoma bodies may be present. Representative examples include cervical serous adenocarcinoma, endometrial serous adenocarcinoma, ovarian serous adenocarcinoma, and primary peritoneal serous adenocarcinoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005278"
    },
    {
      "id": 21609,
      "label": "malignant ovarian serous tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18447,
        22963
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025472",
          "MEDGEN:309396",
          "NCIT:C40025",
          "UMLS:C1518234"
        ],
        "synonyms": [
          "malignant ovarian serous tumor",
          "ovarian serous tumor, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An invasive malignant neoplasm that arises from the ovary and is characterized by the presence of malignant epithelial cells that, in well differentiated tumors, resemble the epithelium of the fallopian tube or, in poorly differentiated tumors, show anaplastic features and marked nuclear atypia. It includes serous adenocarcinoma and serous adenocarcinofibroma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024885"
    }
  ],
  "children": [
    {
      "id": 5738,
      "label": "ovarian serous surface papillary adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4583,
        5686,
        6927
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6408",
          "GARD:0023708",
          "MEDGEN:233279",
          "NCIT:C6256",
          "UMLS:C1335178"
        ],
        "synonyms": [
          "ovarian serous surface papillary adenocarcinoma",
          "ovary papillary carcinoma",
          "serous surface papillary carcinoma of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A serous adenocarcinoma that arises from the ovary and is characterized by the presence of a papillary architectural pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003874"
    },
    {
      "id": 7632,
      "label": "ovarian serous cystadenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4744,
        6927,
        21536
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5746",
          "EFO:1000043",
          "GARD:0024274",
          "MEDGEN:83541",
          "NCIT:C7978",
          "UMLS:C0279663"
        ],
        "synonyms": [
          "ovarian serous cystadenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant serous cystic epithelial neoplasm arising from the ovary. It is characterized by the presence of glandular, papillary, or solid structures. Psammoma bodies may be present. In well differentiated cases the malignant epithelial cells resemble the cells of fallopian tube epithelium. In poorly differentiated cases the malignant epithelial cells show anaplastic features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006046"
    },
    {
      "id": 18449,
      "label": "primary peritoneal serous/papillary carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6927,
        7906
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6228",
          "GARD:0021653",
          "MEDGEN:237154",
          "NCIT:C7695",
          "Orphanet:398980",
          "UMLS:C1368918"
        ],
        "synonyms": [
          "PPSPC",
          "peritoneal serous papillary adenocarcinoma",
          "primary peritoneal serous papillary adenocarcinoma",
          "primary peritoneal serous papillary carcinoma",
          "primary serous papillary carcinoma of peritoneum"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018368"
    }
  ],
  "roots": [
    {
      "id": 4787,
      "label": "ovarian adenocarcinoma"
    },
    {
      "id": 6974,
      "label": "serous adenocarcinoma"
    },
    {
      "id": 21609,
      "label": "malignant ovarian serous tumor"
    }
  ]
}