{
  "id": 6936,
  "label": "renal pelvis urothelial carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005221",
  "properties": {
    "xrefs": [
      "DOID:5974",
      "EFO:0003017",
      "GARD:0024167",
      "ICD9:189.0",
      "MEDGEN:1648131",
      "NCIT:C7355",
      "SCTID:408642003",
      "UMLS:C4087468"
    ],
    "synonyms": [
      "kidney renal pelvis urothelial cancer",
      "renal pelvis transitional cell carcinoma",
      "renal pelvis urothelial cancer",
      "renal pelvis urothelial carcinoma",
      "transitional cell carcinoma of renal pelvis",
      "transitional cell carcinoma of the renal pelvis",
      "urothelial cell carcinoma of renal pelvis",
      "urothelial cell carcinoma of the renal pelvis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A carcinoma that arises from the transitional epithelium of the renal pelvis. It is associated with tobacco use and usually presents with gross or microscopic hematuria. Urothelial carcinomas of the renal pelvis are usually of higher grade and higher stage compared to bladder urothelial carcinomas."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7174,
      "label": "renal pelvis carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6923,
        23480
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4919",
          "EFO:0005582",
          "ICD10CM:C65",
          "ICD9:189.1",
          "MEDGEN:235548",
          "NCIT:C6142",
          "SCTID:363457009",
          "UMLS:C1335749"
        ],
        "synonyms": [
          "cancer of renal pelvis",
          "malignant neoplasm of renal pelvis",
          "malignant renal pelvis neoplasm",
          "malignant tumour of renal pelvis",
          "renal pelvis cancer",
          "carcinoma of kidney pelvis",
          "carcinoma of renal pelvis",
          "carcinoma of the kidney pelvis",
          "carcinoma of the renal pelvis",
          "kidney pelvis carcinoma",
          "kidney renal pelvis cancer",
          "renal pelvis carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A carcinoma arising in the renal pelvis. The majority of renal pelvis carcinomas are transitional cell and less frequently squamous cell carcinomas."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005519"
    },
    {
      "id": 20068,
      "label": "renal pelvis/ureter urothelial carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23006
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009376",
          "NCIT:C7716",
          "ONCOTREE:UTUC",
          "Orphanet:598216"
        ],
        "synonyms": [
          "TCC of renal pelvis and ureter",
          "TCC of the renal pelvis and ureter",
          "UTUC",
          "renal pelvis and ureter TCC",
          "renal pelvis and ureter transitional cell cancer",
          "renal pelvis and ureter transitional cell carcinoma",
          "renal pelvis and ureter urothelial carcinoma",
          "transitional cell cancer of renal pelvis and ureter",
          "transitional cell cancer of the renal pelvis and ureter",
          "transitional cell carcinoma of renal pelvis and ureter",
          "transitional cell carcinoma of the pelvis and ureter",
          "transitional cell carcinoma of the upper urinary tract",
          "upper tract urothelial carcinoma",
          "urothelial carcinoma of the renal pelvis and ureter"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A transitional cell carcinoma that arises from the renal pelvis and ureter."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020654"
    }
  ],
  "children": [
    {
      "id": 2880,
      "label": "infiltrating renal pelvis transitional cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5860,
        6936
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050620",
          "GARD:0022760"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A infiltrating urothelial carcinoma that involves the renal pelvis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000381"
    },
    {
      "id": 5597,
      "label": "renal pelvis papillary urothelial carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5598,
        6936,
        7876
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5973",
          "GARD:0023630",
          "MEDGEN:237178",
          "NCIT:C6148",
          "UMLS:C1377909"
        ],
        "synonyms": [
          "kidney pelvis papillary carcinoma",
          "papillary carcinoma of kidney pelvis",
          "papillary carcinoma of renal pelvis",
          "papillary carcinoma of the kidney pelvis",
          "papillary carcinoma of the renal pelvis",
          "renal pelvis papillary carcinoma",
          "renal pelvis papillary urothelial carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A papillary transitional cell carcinoma that arises from the renal pelvis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003716"
    },
    {
      "id": 5859,
      "label": "kidney pelvis sarcomatoid transitional cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4854,
        6936
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6844",
          "GARD:0023773",
          "MEDGEN:233403",
          "NCIT:C6186",
          "UMLS:C1335752"
        ],
        "synonyms": [
          "infiltrating renal pelvis urothelial carcinoma, sarcomatoid variant",
          "kidney pelvis sarcomatoid transitional cell carcinoma",
          "renal pelvis sarcomatoid transitional cell carcinoma",
          "sarcomatoid transitional cell carcinoma of kidney pelvis",
          "sarcomatoid transitional cell carcinoma of renal pelvis",
          "sarcomatoid transitional cell carcinoma of the kidney pelvis",
          "sarcomatoid transitional cell carcinoma of the renal pelvis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An infiltrating transitional cell carcinoma that arises from the renal pelvis and exhibits sarcomatoid features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004009"
    }
  ],
  "roots": [
    {
      "id": 7174,
      "label": "renal pelvis carcinoma"
    },
    {
      "id": 20068,
      "label": "renal pelvis/ureter urothelial carcinoma"
    }
  ]
}