{
  "id": 6944,
  "label": "non-small cell lung carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005233",
  "properties": {
    "xrefs": [
      "DOID:3908",
      "EFO:0003060",
      "HP:0030358",
      "MEDGEN:40104",
      "MESH:D002289",
      "NCIT:C2926",
      "ONCOTREE:NSCLC",
      "Orphanet:488201",
      "SCTID:254637007",
      "UMLS:C0007131"
    ],
    "synonyms": [
      "NSCLC",
      "NSCLC - non-small cell lung cancer",
      "non-small cell cancer of lung",
      "non-small cell cancer of the lung",
      "non-small cell carcinoma of lung",
      "non-small cell carcinoma of the lung",
      "non-small cell lung cancer",
      "non-small cell lung carcinoma",
      "non-small cell lung carcinoma (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6862,
      "label": "lung carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        10167
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3905",
          "EFO:0001071",
          "MEDGEN:195765",
          "NCIT:C4878",
          "UMLS:C0684249",
          "icd11.foundation:947165291"
        ],
        "synonyms": [
          "cancer of lung",
          "cancer of the lung",
          "lung cancer",
          "lung cancer, NOS",
          "carcinoma of lung",
          "carcinoma of the lung",
          "lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the lung"
      },
      "child_count": 20,
      "reference_id": "MONDO:0005138"
    }
  ],
  "children": [
    {
      "id": 5040,
      "label": "lung large cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6943,
        6944
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4556",
          "EFO:0003050",
          "ICD9:162.9",
          "MEDGEN:91060",
          "NCIT:C4450",
          "ONCOTREE:LCLC",
          "SCTID:254629004",
          "UMLS:C0345958"
        ],
        "synonyms": [
          "anaplastic lung carcinoma",
          "large cell carcinoma of lung",
          "large cell carcinoma of the lung",
          "large cell lung cancer",
          "large cell lung carcinoma",
          "large cell undifferentiated lung carcinoma",
          "lung large cell carcinoma",
          "LCLC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A poorly differentiated non-small cell lung carcinoma composed of large polygonal cells without evidence of glandular or squamous differentiation. There is a male predilection."
      },
      "child_count": 14,
      "reference_id": "MONDO:0003050"
    },
    {
      "id": 6791,
      "label": "lung adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6944
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3910",
          "EFO:0000571",
          "MEDGEN:57744",
          "MESH:C538231",
          "NCIT:C3512",
          "ONCOTREE:LUAD",
          "Orphanet:415268",
          "SCTID:254626006",
          "UMLS:C0152013"
        ],
        "synonyms": [
          "adenocarcinoma of lung",
          "adenocarcinoma of the lung",
          "lung adenocarcinoma",
          "non-small cell lung adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005061"
    },
    {
      "id": 23667,
      "label": "non-small cell squamous lung carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6824,
        6944
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080521",
          "MEDGEN:1383559",
          "NCIT:C133254",
          "SCTID:723301009",
          "UMLS:C4509816"
        ],
        "synonyms": [
          "non-small cell squamous lung cancer",
          "non-small cell squamous lung carcinoma",
          "squamous non-small cell lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma that arises from the lung. It is characterized by the presence of large malignant cells. It includes the clear cell and papillary variants of squamous cell carcinoma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0056806"
    }
  ],
  "roots": [
    {
      "id": 6862,
      "label": "lung carcinoma"
    }
  ]
}