{
  "id": 6948,
  "label": "kidney disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005240",
  "properties": {
    "xrefs": [
      "DOID:557",
      "EFO:0003086",
      "ICD9:583.81",
      "MEDGEN:9635",
      "MESH:D007674",
      "NCIT:C3149",
      "SCTID:90708001",
      "UMLS:C0022658"
    ],
    "synonyms": [
      "disease of kidney",
      "disease or disorder of kidney",
      "disorder of kidney",
      "kidney disease",
      "kidney disease or disorder",
      "kidney disorder",
      "renal disease",
      "renal disorder",
      "nephropathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A disease involving the kidney."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 57,
  "parents": [
    {
      "id": 4253,
      "label": "urinary system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:18",
          "EFO:0009690",
          "ICD9:V47.4",
          "MEDGEN:21791",
          "MESH:D014570",
          "NCIT:C3430",
          "SCTID:128606002",
          "UMLS:C0042075"
        ],
        "synonyms": [
          "disease of renal system",
          "disease or disorder of renal system",
          "disease, urinary tract",
          "disease, urologic",
          "disease, urological",
          "diseases, urinary tract",
          "diseases, urologic",
          "diseases, urological",
          "disorder of renal system",
          "disorder of the urinary system",
          "disorder of urinary system",
          "renal system disease",
          "renal system disease or disorder",
          "urinary disease",
          "urinary system disorder",
          "urinary tract disease",
          "urinary tract diseases",
          "urinary tract disorder",
          "urologic disease",
          "urologic disorder",
          "urological disease",
          "urological diseases",
          "urological disorder",
          "urological disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease involving the renal system."
      },
      "child_count": 20,
      "reference_id": "MONDO:0002118"
    }
  ],
  "children": [
    {
      "id": 3355,
      "label": "renal hypertension",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3441,
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1073",
          "EFO:1002039",
          "MEDGEN:5700",
          "MESH:D006977",
          "NANDO:2100016",
          "NANDO:2200141",
          "SCTID:28119000",
          "UMLS:C0020544"
        ],
        "synonyms": [
          "renovascular hypertension"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Hypertension caused by the kidney's hormonal response to narrowing or occlusion of the renal arteries."
      },
      "child_count": 6,
      "reference_id": "MONDO:0001105"
    },
    {
      "id": 3356,
      "label": "kidney failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1074",
          "EFO:1002048",
          "ICD9:404.12",
          "ICD9:404.13",
          "ICD9:586",
          "MEDGEN:11177",
          "MESH:D051437",
          "NCIT:C4376",
          "SCTID:42399005",
          "UMLS:C0035078",
          "icd11.foundation:761526554"
        ],
        "synonyms": [
          "failure, renal",
          "renal failure",
          "renal failure syndrome",
          "renal insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001106"
    },
    {
      "id": 3410,
      "label": "nephritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10952",
          "EFO:1002050",
          "ICD9:583.7",
          "ICD9:583.89",
          "ICD9:583.9",
          "MEDGEN:14328",
          "MESH:D009393",
          "NCIT:C26833",
          "SCTID:52845002",
          "UMLS:C0027697"
        ],
        "synonyms": [
          "inflammation of kidney",
          "kidney inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Inflammation of renal tissue."
      },
      "child_count": 8,
      "reference_id": "MONDO:0001166"
    },
    {
      "id": 3571,
      "label": "impaired renal function disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11705",
          "ICD10CM:N25",
          "ICD9:588.8",
          "ICD9:588.89",
          "ICD9:588.9",
          "MEDGEN:574572",
          "SCTID:197663003",
          "UMLS:C0341677"
        ],
        "synonyms": [
          "disease of kidney",
          "kidney disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Any disease in which the causes of the disease is a perturbation of the kidney leading to its dysfunction."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001343"
    },
    {
      "id": 3772,
      "label": "nephrocalcinosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4258,
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12679",
          "ICD9:275.49",
          "MEDGEN:10222",
          "MESH:D009397",
          "NCIT:C84918",
          "SCTID:48638002",
          "UMLS:C0027709",
          "icd11.foundation:1359282431"
        ],
        "synonyms": [
          "hypercalcemic nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Nephrocalcinosis is a disorder that occurs when too much calcium is deposited in the kidneys. It commonly occurs in premature infants. Individuals may not have symptoms or may have symptoms related to thecondition causing nephrocalcinosis. If kidney stones are present, symptoms may include blood in the urine, fever and chills, nausea and vomiting, and severe pain in the belly area, sides of the back (flank), groin, or testicles. Later symptoms may be associated with chronic kidney failure. It may be caused by use of certain medications or supplements, infection, or any condition that leads to high levels of calcium in the blood or urine including hyperparathyroidism, renal tubular acidosis, Alport syndrome, Bartter syndrome,and a variety of other conditions. Some of the underlying disorders that can cause nephrocalcinosis are genetic, with the inheritance pattern depending on the specific disorder. Treatment differs depending on the cause of nephrocalcinosis and often aims to prevent more calcium from being deposited in the kidneys."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001567"
    },
    {
      "id": 4161,
      "label": "atheroembolism of kidney",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948,
        7216
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1460",
          "ICD10CM:I75.81",
          "MEDGEN:541484",
          "UMLS:C0268792"
        ],
        "synonyms": [
          "cholesterol embolism of kidney",
          "kidney cholesterol embolism"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A cholesterol embolism that involves the kidney."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002004"
    },
    {
      "id": 4399,
      "label": "renal artery disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        7210
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2388",
          "ICD9:593.81",
          "MEDGEN:768693",
          "NCIT:C101254",
          "SCTID:16934004",
          "UMLS:C3640053"
        ],
        "synonyms": [
          "vascular disorder of kidney"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the renal artery."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002286"
    },
    {
      "id": 4437,
      "label": "nephrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2527",
          "MEDGEN:10223",
          "MESH:D009401",
          "UMLS:C0027720"
        ],
        "synonyms": [
          "Nephroses"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA."
      },
      "child_count": 1,
      "reference_id": "MONDO:0002331"
    },
    {
      "id": 4553,
      "label": "cystic kidney disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2975",
          "EFO:0008615",
          "ICD10CM:Q61",
          "ICD10WHO:Q61",
          "MEDGEN:854361",
          "MESH:D052177",
          "NANDO:2200172",
          "NCIT:C34750",
          "SCTID:722223000",
          "UMLS:C3887499"
        ],
        "synonyms": [
          "cystic renal disease",
          "kidney cyst"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A congenital or acquired kidney disorder characterized by the presence of renal cysts."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002473"
    },
    {
      "id": 4556,
      "label": "anuria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2983",
          "EFO:0009530",
          "MEDGEN:358",
          "MESH:D001002",
          "UMLS:C0003460",
          "icd11.foundation:248693056"
        ],
        "synonyms": [
          "suppression of urinary secretion"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Absence of urine output."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002476"
    },
    {
      "id": 4721,
      "label": "stricture or kinking of ureter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3508",
          "ICD9:593.3",
          "MEDGEN:574605",
          "UMLS:C0341728"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0002674"
    },
    {
      "id": 5523,
      "label": "proteinuria",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:576",
          "ICD10CM:R80",
          "ICD9:791.0",
          "MEDGEN:10976",
          "MESH:D011507",
          "UMLS:C0033687",
          "icd11.foundation:930895737"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "The presence of abnormal amounts of protein in the urine."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003634"
    },
    {
      "id": 6182,
      "label": "renal infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        24067
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:782",
          "ICD9:590",
          "ICD9:590.9",
          "MEDGEN:507844",
          "UMLS:C0021313"
        ],
        "synonyms": [
          "infectious disease of kidney",
          "kidney infectious disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An infectious disease that involves the kidney."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004369"
    },
    {
      "id": 6550,
      "label": "diabetes insipidus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9409",
          "ICD10CM:E23.2",
          "ICD9:253.5",
          "MEDGEN:8349",
          "MESH:D003919",
          "NANDO:2100117",
          "NCIT:C43263",
          "SCTID:15771004",
          "UMLS:C0011848"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disorder characterized by excretion of large amounts of urine, accompanied by excessive thirst. Causes include deficiency of antidiuretic hormone or failure of the kidneys to respond to antidiuretic hormone. It may also be drug-related."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004782"
    },
    {
      "id": 6596,
      "label": "orthostatic proteinuria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9617",
          "ICD9:593.6",
          "MEDGEN:534880",
          "UMLS:C0232867",
          "icd11.foundation:2144070055"
        ],
        "synonyms": [
          "postural albuminuria"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0004838"
    },
    {
      "id": 6598,
      "label": "kidney hypertrophy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9622",
          "ICD10CM:N28.81",
          "ICD9:593.1",
          "MEDGEN:510218",
          "NCIT:C122991",
          "SCTID:88531004",
          "UMLS:C0156259"
        ],
        "synonyms": [
          "hypertrophy of the kidney",
          "renal Hypertrophy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Global enlargement of the renal parenchyma in one or both kidneys."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004841"
    },
    {
      "id": 6994,
      "label": "chronic kidney disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:784",
          "EFO:0003884",
          "ICD10CM:N18",
          "ICD10CM:N18.9",
          "ICD10WHO:N18",
          "ICD9:585",
          "MEDGEN:473458",
          "MESH:D007676",
          "NANDO:2100008",
          "NANDO:2100023",
          "NCIT:C80078",
          "SCTID:709044004",
          "UMLS:C1561643",
          "icd11.foundation:412389819"
        ],
        "synonyms": [
          "CKD - chronic kidney disease",
          "chronic kidney disease",
          "chronic renal disease",
          "kidney disease, chronic",
          "chronic renal failure syndrome",
          "chronic renal insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Impairment of the renal function secondary to chronic kidney damage persisting for three or more months."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005300"
    },
    {
      "id": 7166,
      "label": "hydronephrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5268,
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11111",
          "EFO:0005562",
          "ICD9:591",
          "MEDGEN:42531",
          "MESH:D006869",
          "NCIT:C26796",
          "SCTID:43064006",
          "UMLS:C0020295"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005510"
    },
    {
      "id": 8001,
      "label": "renal tubular transport disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:447",
          "EFO:1000647",
          "MEDGEN:19728",
          "MESH:D015499",
          "UMLS:C0035091"
        ],
        "synonyms": [
          "disorder of renal absorption",
          "renal absorption disease",
          "kidney tubular transport, inborn error",
          "kidney tubular transport, inborn errors",
          "renal tubular transport errors",
          "renal tubular transport, inborn error"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Genetic defects in the selective or non-selective transport functions of the kidney tubules."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006510"
    },
    {
      "id": 8266,
      "label": "kidney cortex necrosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2973",
          "ICD9:583.6",
          "MEDGEN:9634",
          "MESH:D007673",
          "MedDRA:10023414",
          "SCTID:444691002",
          "UMLS:C0022656"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Death of cells in the kidney cortex, a common final result of various renal injuries including hypoxia; ischemia; and drug toxicity."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006820"
    },
    {
      "id": 8267,
      "label": "kidney papillary necrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2981",
          "ICD9:583.7",
          "MEDGEN:7212",
          "MESH:D007681",
          "MedDRA:10028865",
          "SCTID:90241004",
          "UMLS:C0022667"
        ],
        "synonyms": [
          "renal papillitis necrotizing"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A complication of kidney diseases characterized by cell death involving kidney papilla in the kidney medulla. Damages to this area may hinder the kidney to concentrate urine resulting in polyuria. Sloughed off necrotic tissue may block kidney pelvis or ureter. Necrosis of multiple renal papillae can lead to kidney failure."
      },
      "child_count": 1,
      "reference_id": "MONDO:0006821"
    },
    {
      "id": 8338,
      "label": "perinephritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2982",
          "EFO:1001099",
          "MEDGEN:10656",
          "MESH:D010501",
          "MedDRA:10072058",
          "SCTID:111404004",
          "UMLS:C0031065"
        ],
        "synonyms": [
          "inflammation of perirenal fat",
          "perirenal fat inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Inflammation of the connective and adipose tissues surrounding the kidney."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006900"
    },
    {
      "id": 8373,
      "label": "renal aminoaciduria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006774",
          "MEDGEN:254",
          "MESH:D000608",
          "MedDRA:10001939",
          "SCTID:35912001",
          "UMLS:C0002534"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A group of inherited kidney disorders characterized by the abnormally elevated levels of amino acids in urine. Genetic mutations of transport proteins result in the defective reabsorption of free amino acids at the proximal renal tubules. Renal aminoaciduria are classified by the specific amino acid or acids involved."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006944"
    },
    {
      "id": 9393,
      "label": "autosomal dominant progressive nephropathy with hypertension",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016772",
          "ICD9:583.9",
          "MEDGEN:98012",
          "MESH:C562889",
          "OMIM:161900",
          "Orphanet:88659",
          "SCTID:703310005",
          "UMLS:C0403443",
          "icd11.foundation:1997246041"
        ],
        "synonyms": [
          "nephropathy-hypertension",
          "RFH1",
          "nephritis, familial, without deafness or ocular defect",
          "nephropathy, familial",
          "renal failure, adult-onset",
          "renal failure, progressive, with hypertension"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008071"
    },
    {
      "id": 9482,
      "label": "nephrolithiasis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        21555
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:585",
          "EFO:0004253",
          "ICD9:592",
          "MEDGEN:98227",
          "MESH:D053040",
          "NCIT:C114667",
          "SCTID:266556005",
          "UMLS:C0392525"
        ],
        "synonyms": [
          "calculus of kidney and ureter",
          "kidney stone",
          "renal calculi",
          "CAON",
          "nephrolithiasis, calcium oxalate",
          "urolithiasis, calcium oxalate"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins."
      },
      "child_count": 6,
      "reference_id": "MONDO:0008171"
    },
    {
      "id": 11787,
      "label": "X-linked diffuse leiomyomatosis-Alport syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        17410
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002432",
          "MEDGEN:333429",
          "MESH:C537113",
          "OMIM:308940",
          "Orphanet:1018",
          "UMLS:C1839884"
        ],
        "synonyms": [
          "Xq22.3 microdeletion syndrome",
          "ATS-DL",
          "Alport syndrome and diffuse leiomyomatosis",
          "Alport syndrome with diffuse leiomyomatosis",
          "DL-ATS",
          "chromosome Xq22.3 centromeric deletion syndrome",
          "diffuse leiomyomatosis in Alport syndrome",
          "leiomyomatosis, diffuse, with Alport syndrome",
          "leiomyomatosis, esophageal and vulval, with nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare renal disease characterized by the association of X-linked Alport syndrome (glomerular nephropathy, sensorineural deafness and ocular anomalies) and benign proliferation of visceral smooth muscle cells along the gastrointestinal, respiratory, and female genital tracts and clinically manifests with dysphagia, dyspnea, cough, stridor, postprandial vomiting, retrosternal or epigastric pain, recurrent pneumonia, and clitoral hypertrophy in females."
      },
      "child_count": 2,
      "reference_id": "MONDO:0010641"
    },
    {
      "id": 12962,
      "label": "tubulointerstitial nephritis and uveitis syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009252",
          "MEDGEN:334715",
          "MESH:C536922",
          "MedDRA:10069034",
          "MedDRA:10069039",
          "NCIT:C123021",
          "OMIM:607665",
          "Orphanet:91500",
          "UMLS:C1843273"
        ],
        "synonyms": [
          "Dobrin syndrome",
          "TINU syndrome",
          "Tubulointerstitial nephritis and uveitis",
          "acute tubulointerstitial nephritis and uveitis syndrome",
          "TINU",
          "TUBULOINTERSTITIAL nephritis with uveitis",
          "acute Tubulointerstitial nephritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "An autoimmune disorder comprising tubulointerstitial nephritis and uveitis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011885"
    },
    {
      "id": 16574,
      "label": "distal renal tubular acidosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0004667",
          "HP:0008341",
          "ICD9:588.89",
          "MEDGEN:853429",
          "MedDRA:10045224",
          "NORD:1969",
          "Orphanet:18",
          "SCTID:236461000",
          "UMLS:C1704380"
        ],
        "synonyms": [
          "Primary Distal Renal Tubular Acidosis",
          "classic RTA",
          "dRTA",
          "distal renal tubular acidosis (disease)",
          "familial distal primary acidosis",
          "renal tubular acidosis type 1",
          "renal tubular acidosis, distal"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A kidney disorder of impaired net acid secretion by the distal tubule characterized by hyperchloremic metabolic acidosis. Primary distal renal tubular acidosis is often associated with hypokalemia whereas acquired form may be associated with hypokalemia, hyperkalemia or normokalemia."
      },
      "child_count": 2,
      "reference_id": "MONDO:0015827"
    },
    {
      "id": 16925,
      "label": "oligomeganephronia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0111142",
          "GARD:0004066",
          "MEDGEN:609100",
          "NANDO:2200159",
          "NCIT:C123202",
          "Orphanet:2260",
          "SCTID:18417009",
          "UMLS:C0431694",
          "icd11.foundation:1283447040"
        ],
        "synonyms": [
          "Oligomeganephronic renal hypoplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Oligomeganephronia is a developmental anomaly of the kidneys, and the most severe form of renal hypoplasia, characterized by a reduction of 80% in nephron number and a marked hypertrophy of the glomeruli and tubules."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016407"
    },
    {
      "id": 17026,
      "label": "duplication of urethra",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0001975",
          "ICD9:753.8",
          "MEDGEN:75609",
          "Orphanet:237",
          "SCTID:69015003",
          "UMLS:C0266348",
          "icd11.foundation:2069509755"
        ],
        "synonyms": [
          "urethral duplication"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Duplication of the urethra is a rare congenital genitourinary anomaly, encompassing a wide spectrum of anatomic variants in which the urethra is partially or totally duplicated, which may be asymptomatic or cause symptoms such as incontinence, recurrent urinary infections and difficulty urinating."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016529"
    },
    {
      "id": 17886,
      "label": "renal tubular dysgenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000379",
          "MEDGEN:82738",
          "Orphanet:3033",
          "SCTID:702397002",
          "UMLS:C0266313",
          "icd11.foundation:191424358"
        ],
        "synonyms": [
          "primitive renal tubule syndrome",
          "renotubular dysgenesis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Renal tubular dysgenesis is a rare disorder of the fetus characterized by absent or poorly developed proximal tubules of the kidneys, persistent oligohydramnios, leading to Potter sequence (facial dysmorphism with large and flat low-set ears, lung hypoplasia arthrogryposis and limb positioning defects), and skull ossification defects. It can be acquired during fetal development due to drugs taken by the mother or certain disorders (twin-twin transfusion syndrome, TTTS) or inherited in an autosomal recessive manner."
      },
      "child_count": 3,
      "reference_id": "MONDO:0017609"
    },
    {
      "id": 18120,
      "label": "exstrophy-epispadias complex",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        19192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080173",
          "GARD:0002207",
          "MEDGEN:338020",
          "NCIT:C99142",
          "OMIM:258040",
          "Orphanet:322",
          "UMLS:C1850321"
        ],
        "synonyms": [
          "EEC",
          "OEIS complex",
          "OEIS syndrome",
          "BEEC",
          "bladder exstrophy-epispadias-cloacal extrophy complex"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A spectrum of genitourinary malformations ranging in severity from epispadias (E) and classical bladder exstrophy (CEB) to exstrophy of the cloaca (EC) as the most severe form. Depending on severity, the EEC may involve the urinary system, the musculoskeletal system, the pelvis, the pelvic floor, the abdominal wall, the genitalia and sometimes the spine and the anus."
      },
      "child_count": 8,
      "reference_id": "MONDO:0017919"
    },
    {
      "id": 18571,
      "label": "fetal lower urinary tract obstruction",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        19192
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021804",
          "MEDGEN:931214",
          "Orphanet:435365",
          "SCTID:717752005",
          "UMLS:C4305545",
          "icd11.foundation:1661120971"
        ],
        "synonyms": [
          "LUTO"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 10,
      "reference_id": "MONDO:0018559"
    },
    {
      "id": 18662,
      "label": "IgG4-related kidney disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948,
        17611
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021882",
          "MEDGEN:1708840",
          "NANDO:1200930",
          "Orphanet:449395",
          "UMLS:C5392056",
          "icd11.foundation:1877692678"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018671"
    },
    {
      "id": 18882,
      "label": "congenital primary megaureter",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018700",
          "MEDGEN:903364",
          "NANDO:2200184",
          "Orphanet:617",
          "SCTID:717459000",
          "UMLS:C4273898",
          "icd11.foundation:566805920"
        ],
        "synonyms": [
          "congenital primary megalo-ureter",
          "CGM",
          "congenital giant megaureter",
          "congenital megalo-ureter"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An idiopathic condition in which the bladder and bladder outlet are normal but the ureter is dilated to some extent. It may be obstructed, refluxing or unobstructed and not refluxing."
      },
      "child_count": 10,
      "reference_id": "MONDO:0018960"
    },
    {
      "id": 18991,
      "label": "renal nutcracker syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001838",
          "GARD:0011971",
          "MEDGEN:465238",
          "MESH:D059228",
          "Orphanet:71273",
          "SCTID:717267005",
          "UMLS:C3178770"
        ],
        "synonyms": [
          "RNS",
          "left renal vein entrapment syndrome",
          "nutcracker syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare, syndromic renal disease characterized by the entrapment of left renal vein (LRV) between the superior mesenteric artery (SMA) and the abdominal aorta, resulting in increased luminal pressure, renal hilar varices, hematuria and, at the microscopic level, rupture of thin-walled veins into the collecting system in renal fornices."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019105"
    },
    {
      "id": 19427,
      "label": "renal hypoplasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080204",
          "GARD:0019172",
          "HP:0000089",
          "MEDGEN:120571",
          "MedDRA:10049102",
          "NANDO:2200155",
          "Orphanet:93101",
          "SCTID:32659003",
          "UMLS:C0266295"
        ],
        "synonyms": [
          "renal hypoplasia",
          "renal hypoplasia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Renal hypoplasia is a developmental anomaly in which one or both kidneys (unilateral or bilateral renal hypoplasia, respectively) have a deficit in the number of nephrons and may be small. Oligomeganephronia represents a severe variant of hypoplasia in which nephron number is reduced by 80% and nephrons are markedly hypertrophied."
      },
      "child_count": 4,
      "reference_id": "MONDO:0019637"
    },
    {
      "id": 19428,
      "label": "renal dysplasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019173",
          "HP:0000110",
          "ICD10CM:Q61.4",
          "MEDGEN:760690",
          "NANDO:2200161",
          "Orphanet:93108",
          "UMLS:C3536714",
          "icd11.foundation:921320354"
        ],
        "synonyms": [
          "renal dysplasia",
          "renal dysplasia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Renal dysplasia is a form of renal malformation in which the kidney(s) are present but their development is abnormal and incomplete. Renal dysplasia can be unilateral or bilateral, segmental, and of variable severity, with renal aplasia corresponding to extreme dysplasia."
      },
      "child_count": 4,
      "reference_id": "MONDO:0019638"
    },
    {
      "id": 19429,
      "label": "congenital megacalycosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019174",
          "ICD9:753.3",
          "MEDGEN:1782490",
          "NANDO:2200177",
          "Orphanet:93109",
          "SCTID:85901000",
          "UMLS:C5545379",
          "icd11.foundation:954627950"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Congenital megacalycosis is a rare renal malformation, characterized by non-obstructive dilation of the renal calyces as well as an increased calyceal number (12-20), with a normal renal pelvis, ureter, and bladder. It may be unilateral or bilateral and is usually asymptomatic unless complicated by nephrolithiasis and urinary tract infection."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019639"
    },
    {
      "id": 19482,
      "label": "glomerular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1002049",
          "GTR:AN0966176",
          "ICD10CM:N00-N08",
          "MEDGEN:451033",
          "NCIT:C120887",
          "Orphanet:93548",
          "SCTID:197679002",
          "UMLS:C0268731"
        ],
        "synonyms": [
          "disease of renal glomerulus",
          "disease or disorder of renal glomerulus",
          "disorder of renal glomerulus",
          "glomerulopathy",
          "renal glomerulus disease",
          "renal glomerulus disease or disorder",
          "glomerulopathies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease involving the renal glomerulus."
      },
      "child_count": 6,
      "reference_id": "MONDO:0019722"
    },
    {
      "id": 19703,
      "label": "congenital renal artery stenosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948,
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019381",
          "ICD10CM:Q27.1",
          "MEDGEN:635552",
          "Orphanet:97598",
          "SCTID:271432005",
          "UMLS:C0495523",
          "icd11.foundation:856359002"
        ],
        "synonyms": [
          "congenital RAS",
          "congenital renovascular hypoplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A narrowing of renal arteries that is present since birth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019993"
    },
    {
      "id": 20396,
      "label": "kidney neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003865",
          "ICD9:239.5",
          "MEDGEN:5967",
          "NCIT:C3150",
          "ONCOTREE:KIDNEY",
          "SCTID:126880001",
          "UMLS:C0022665"
        ],
        "synonyms": [
          "kidney neoplasm",
          "kidney neoplasm (disease)",
          "kidney tumor",
          "kidney tumour",
          "neoplasm of kidney",
          "neoplasm of the kidney",
          "renal neoplasm",
          "renal tumor",
          "renal tumors",
          "renal tumour",
          "renal tumours",
          "tumor of kidney",
          "tumor of the kidney",
          "tumour of kidney",
          "tumour of the kidney"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma."
      },
      "child_count": 16,
      "reference_id": "MONDO:0021163"
    },
    {
      "id": 20667,
      "label": "renal tubule disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009566",
          "ICD9:588.89",
          "MEDGEN:57484",
          "SCTID:95568003",
          "UMLS:C0151747"
        ],
        "synonyms": [
          "disease of renal tubule",
          "disease or disorder of renal tubule",
          "disorder of renal tubule",
          "renal tubular disease",
          "renal tubular disorder",
          "renal tubule disease",
          "renal tubule disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease that involves the renal tubule."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021568"
    },
    {
      "id": 20743,
      "label": "pyonephrosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:N13.6",
          "MEDGEN:11051",
          "MESH:D053018",
          "NCIT:C123032",
          "SCTID:48631008",
          "UMLS:C0034216",
          "icd11.foundation:809412333"
        ],
        "synonyms": [
          "pyonephrosis",
          "Hydronephrosis, Infected",
          "Infected Hydronephrosis",
          "Pyonephrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Pus within the collecting system of the kidney."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021750"
    },
    {
      "id": 20779,
      "label": "Arnold stickler bourne syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3211,
        4370,
        6139,
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000366",
          "MEDGEN:419426",
          "MESH:C537431",
          "UMLS:C2931492"
        ],
        "synonyms": [
          "corneal crystals myopathy and nephropathy",
          "corneal crystals myopathy and neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0021921"
    },
    {
      "id": 21229,
      "label": "C1q nephropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012136",
          "MEDGEN:588388",
          "SCTID:236412002",
          "UMLS:C0403434"
        ],
        "synonyms": [
          "C1q nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "C1q nephropathy is a kidney disease in which a large amount of protein is lost in the urine. It is one of the many diseases that can cause the nephrotic syndrome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0023551"
    },
    {
      "id": 21544,
      "label": "hypertensive nephropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:403.90",
          "MEDGEN:167258",
          "MESH:C563161",
          "NCIT:C4757",
          "OMIM:608026",
          "SCTID:38481006",
          "UMLS:C0848548"
        ],
        "synonyms": [
          "HNP1",
          "hypertensive nephropathy",
          "hypertensive renal disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Kidney damage that results from chronically elevated blood pressure; complications include glomerular damage resulting in proteinuria and hematuria."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024633"
    },
    {
      "id": 22771,
      "label": "atypical Fanconi syndrome-neonatal hyperinsulinism syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022238",
          "MEDGEN:1830116",
          "Orphanet:544628",
          "UMLS:C5681324"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0034110"
    },
    {
      "id": 22905,
      "label": "idiopathic non-lupus full-house nephropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022285",
          "MEDGEN:1830099",
          "Orphanet:567544",
          "UMLS:C5680132"
        ],
        "synonyms": [
          "Idiopathic non-lupus FHN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035763"
    },
    {
      "id": 23128,
      "label": "lachiewicz sibley syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:419151",
          "MESH:C538131",
          "UMLS:C2931742"
        ],
        "synonyms": [
          "hereditary renal disease and preauricular pits"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0043112"
    },
    {
      "id": 23228,
      "label": "crush syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:3671",
          "MESH:D003444",
          "SCTID:23697004",
          "UMLS:C0010392"
        ],
        "synonyms": [
          "crush syndrome",
          "acute renal failure due to rhabdomyolysis",
          "bywaters' syndrome",
          "crush kidney",
          "crush syndromes",
          "ischaemic muscular necrosis syndrome",
          "ischemic muscular necrosis syndrome",
          "myoglobinuric acute renal failure",
          "myoglobinuric nephrosis",
          "renal failure following crushing injury",
          "syndrome, crush",
          "syndromes, crush"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A medical condition characterized by major shock and renal failure after a crushing injury to skeletal muscle."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043549"
    },
    {
      "id": 23659,
      "label": "obstructive nephropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070314",
          "ICD9:593.89",
          "MEDGEN:508456",
          "NCIT:C120902",
          "SCTID:86249007",
          "UMLS:C0149939",
          "icd11.foundation:848128884"
        ],
        "synonyms": [
          "obstructive nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Renal damage and impaired renal function secondary to urinary tract obstruction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0056796"
    },
    {
      "id": 23932,
      "label": "inherited kidney disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6948
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "genetic renal disease",
          "inherited kidney disease",
          "inherited renal disorder",
          "nephrogenetic disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions, with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology that are characterized by abnormalities in the kidney or urinary system."
      },
      "child_count": 52,
      "reference_id": "MONDO:0100191"
    },
    {
      "id": 24932,
      "label": "acute tubulointerstitial nephritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:334716",
          "UMLS:C1843274"
        ],
        "synonyms": [
          "ATIN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0800337"
    },
    {
      "id": 25161,
      "label": "kidney cortex disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080616"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A kidney disease that is located in the kidney cortex."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850150"
    },
    {
      "id": 25815,
      "label": "non-syndromic supernumerary kidneys",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026924",
          "MEDGEN:1864142",
          "Orphanet:652528",
          "UMLS:C5925122"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0958093"
    },
    {
      "id": 26046,
      "label": "neonatal renal venous thrombosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027178",
          "MEDGEN:1863518",
          "Orphanet:664912",
          "UMLS:C5925061"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0971105"
    }
  ],
  "roots": [
    {
      "id": 4253,
      "label": "urinary system disorder"
    }
  ]
}