{
  "id": 6955,
  "label": "heart failure",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005252",
  "properties": {
    "xrefs": [
      "EFO:0003144",
      "ICD10CM:I50",
      "ICD10WHO:I50",
      "ICD9:428",
      "ICD9:428.9",
      "MEDGEN:6749",
      "MESH:D006333",
      "NCIT:C50577",
      "SCTID:84114007",
      "UMLS:C0018801",
      "icd11.foundation:1458683894"
    ],
    "synonyms": [
      "cardiac failure",
      "cardiac insufficiency",
      "failure, heart",
      "heart failure",
      "insufficiency, Cardiac"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6967,
      "label": "heart disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:114",
          "EFO:0003777",
          "ICD9:429.89",
          "ICD9:429.9",
          "ICD9:V47.2",
          "MEDGEN:5458",
          "MESH:D006331",
          "NCIT:C3079",
          "SCTID:56265001",
          "UMLS:C0018799",
          "icd11.foundation:1512587470"
        ],
        "synonyms": [
          "cardiac disease",
          "disease of heart",
          "disease or disorder of heart",
          "disorder of heart",
          "disorder of heart/pericardium",
          "heart disease",
          "heart disease or disorder",
          "heart disorder",
          "heart trouble",
          "heart/pericardial disease",
          "heart/pericardial disease or disorder",
          "heart/pericardial disorder",
          "heart/pericardial trouble"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the heart and/or pericardium."
      },
      "child_count": 34,
      "reference_id": "MONDO:0005267"
    }
  ],
  "children": [
    {
      "id": 6747,
      "label": "congestive heart failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6955
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6000",
          "EFO:0000373",
          "HP:0001635",
          "ICD9:404.01",
          "ICD9:404.11",
          "ICD9:404.13",
          "ICD9:428",
          "ICD9:428.0",
          "MEDGEN:9169",
          "NCIT:C3080",
          "SCTID:42343007",
          "UMLS:C0018802",
          "icd11.foundation:2136808878"
        ],
        "synonyms": [
          "CHF",
          "cardiac failure, congestive",
          "congestive heart disease",
          "failure, congestive heart",
          "heart failure, congestive"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Failure of the heart to pump a sufficient amount of blood to meet the needs of the body tissues, resulting in tissue congestion and edema. Signs and symptoms include shortness of breath, pitting edema, enlarged tender liver, engorged neck veins, and pulmonary rales."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005009"
    },
    {
      "id": 6956,
      "label": "high output heart failure",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6955
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003145",
          "ICD10CM:I50.83",
          "MEDGEN:526135",
          "SCTID:10091002",
          "UMLS:C0221045",
          "Wikipedia:High-output_cardiac_failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "High-output heart failure is a heart condition that occurs when the cardiac output is higher than normal."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005253"
    },
    {
      "id": 6957,
      "label": "symptomatic heart failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6955
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003146"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heart failure which results in symptoms such as shortness of breath, fatigue, inability to exerciseb& etc"
      },
      "child_count": 3,
      "reference_id": "MONDO:0005254"
    },
    {
      "id": 23279,
      "label": "cardio-renal syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        6955
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:453248",
          "MESH:D059347",
          "NCIT:C123225",
          "SCTID:445236007",
          "UMLS:C2242703"
        ],
        "synonyms": [
          "cardiorenal syndrome",
          "Reno Cardiac syndrome",
          "Reno-Cardiac syndrome",
          "Reno-Cardiac syndromes",
          "Renocardiac syndrome",
          "Renocardiac syndromes",
          "cardio renal syndrome",
          "cardio-renal syndromes",
          "cardiorenal syndromes",
          "syndrome, Reno-Cardiac",
          "syndrome, Renocardiac",
          "syndrome, cardio-renal",
          "syndrome, cardiorenal",
          "syndromes, Reno-Cardiac",
          "syndromes, Renocardiac",
          "syndromes, cardio-renal",
          "syndromes, cardiorenal"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disorder of the heart and kidneys in which dysfunction of one of the organs induces dysfunction of the other organ."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044079"
    }
  ],
  "roots": [
    {
      "id": 6967,
      "label": "heart disorder"
    }
  ]
}